Document Type : Original Article

Authors

1 Rajaie Cardiovascular Medical and Research Center, Iran university of medical sciences, Tehran, Iran

2 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran

3 Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran

10.48305/arya.2024.42018.2915

Abstract

Abstract:

Background: Atrial fibrillation (AF) increases stroke risk by 4-5 times. Vitamin D has a crucial role in multiple metabolic pathways. A few studies have investigated the association of vitamin D deficiency (VDD) and AF outcome. Therefore, we aimed to evaluate the VDD association and the AF outcome.

Methods: Between December 2021 and February 2023, 190 patients with AF were enrolled in our study. In view of vitamin D seasonal change, vitamin D levels were studied from the beginning of December until the end of March.

Results: Among the whole study population, Vitamin D deficiency, insufficiency and sufficiency were seen in 77 (40.5%), 46 (24.2%), and 67 (35.3%) patients, respectively. Fatigue and syncope were significantly higher in the VDD group than in other groups. The three-vessel disease was more common in VDD groups (p-value=0.04). Mortality was more common in patients with VDD (6.31%) compared with the VDI (2.10%) and VDS (0.05%) groups (p = 0.03). Successful cardioversion is significantly more common in the VDS group (p = 0.03).

Conclusion: An adequate level of vitamin D was associated with a better response to cardioversion; however, low vitamin D levels are associated with higher mortality in AF patients.

Keywords