Document Type : Review Article

Authors

1 Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences ,Isfahan ,Iran

2 1Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences ,Isfahan ,Iran

3 Hypertension research center, cardiovascular research institute, Isfahan University of Medical Sciences ,Isfahan ,Iran

4 Fellowship of echocardiography, department of cardiology, school of medicine, Chamran hospital ,Isfahan University of Medical Sciences ,Isfahan ,Iran

10.48305/arya.2023.42244.2927

Abstract

Aims: The current systematic review and pooled analysis was carried out to answer several questions using findings from case reports and case series as follows: (1) Demographic characteristics; (2) clinical findings; (3) management approach; and (4) prognosis of individuals diagnosed with intramyocardial dissecting hematoma.

Methods: Available electronic databases including PubMed (Medline), Scopus, and Web of Science were searched systematically from the earliest available date up to February 2023 using selected keywords. All of the analyses were done using SPSS software version 27 (IBM Corp, Armonk, NY, USA) and a P-value less than 0.05 was considered statistically significant.

Results: A total of 77 patients diagnosed with IDH make up our study population with a mean (standard deviation) age of 58.72 (13.99) years of which 22.1% were women. Patients with higher age experienced a higher risk for mortality compared to younger subjects (OR=1.05, 95% CI: 1.01, 1.10; P=0.014). In addition, implementing angiography (OR=0.25, 95% CI: 0.08, 0.71; P=0.010) and cardiac magnetic resonance (OR=0.19, 95% CI: 0.06, 0.60; P=0.004) in the context of diagnosis reduced the risk of death compared to those who didn’t receive these interventions. Likewise, diagnosis of pericardial effusion significantly increased the risk of mortality compared to those without pericardial effusion (OR=3.92, 95% CI: 1.27, 12.07; P=0.017).

Conclusion: older patients experience a poor prognosis compared to younger ones. also, utilizing angiography and cardiac magnetic resonance improves the prognosis . Likewise, diagnosis of pericardial effusion in patients with IDH increases the odds of mortality.

Keywords: Intramyocardial dissecting hematoma; prognosis; systematic review

Keywords