Document Type : Original Article
Authors
- Alireza Ahmadi 1
- Mohammad Reza Sabri, MD 2
- Mehdai Ghaderian 3
- Davood Ramezani Nezhad 3
- Mohsen Sedighi 4
- Bahar Dehghan 3
- Chehreh Mahdavi 3
1 Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
2 Pediatric Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
3 Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
4 Trauma and Injury Research Center, Iran University of Medical Sciences, Tehran, Iran.
Abstract
Background: Balloon pulmonary valvuloplasty (BPV) is performed to treat pulmonary stenosis (PS). We assessed right ventricle (RV) performance by 2D-speckle tracking echocardiography (2D-STE).
Methods: 25 children with PS who underwent BPV and 25 controls were examined by 2D-STE. Linear mixed model (LMM) analysis was applied for evaluating changes in pulmonary valve peak gradient (PVPG), tricuspid annular plane systolic excursion (TAPSE), RV strain and strain rate (SR), and left ventricular ejection fraction (LVEF).
Results: TAPSE (P=0.001), global strain (P =0.001), apical septal strain (P =0.024), middle septal strain (P =0.001), basal septal strain (P =0.001), apical lateral SR (P =0.001), middle lateral SR (P =0.007), basal lateral SR (P =0.001), and apical septal SR (P =0.001) differed notably between two groups. LVEF (P =0.001) and TAPSE (P =0.001) increased while PVPG decreased (P =0.001) post-BPV. Apical lateral strain (P =0.004), middle septal strain (P =0.001), apical septal strain (P =0.003), middle septal strain (P =0.001), basal septal strain (P =0.048), apical septal SR (P =0.025), and middle septal SR (P =0.023) showed an increase following BPV. Gender was significantly related to mean changes in basal lateral strain (P =0.019), middle septal strain (P =0.037), and middle septal SR (P =0.020). Age in the PS group showed a relationship with mean change in basal septal strain (P =0.031) and basal septal SR (P =0.018).
Conclusion: RV strain and SR improved after BPV in PS children. Age and gender of children showed notable effects on changes in RV strain and SR after BPV.
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