Introduction: Hypertension (HPN) is a wide spread, chronic and recurrent disease which is treatable by timely hypertensive medicines. One of the most important problems of patients with HPN is lack of medication adherence; thus the current survey was aimed to investigate related psychological factors associated with medication adherence.Methods: This was a cross-sectional study with 162 participants with HPN from 3 clinics of Isfahan University of Medical Sciences that was performed in 2019. Participants filled out BMQ (Beliefs about Medicines Questionnaire), MMAS (Morisky Medication Adherence Scale), CFQ (Cognitive Fusion Questionnaire) and VLQ (Valued Living Questionnaire). Descriptive statistics, chi-square and analysis of variance tests and also simple linear and multivariable regression analyses and correlation coefficients were used for analyzing the data.Results: Only 22.2% of patients got high score in medication adherence. Level of medication adherence increases with age in a significant correlation (p=0.03) and also a significant positive relevancy exists between medication adherence and average scores of importance of person valued living and time allocation for values (p= 0.012 and 0.03 respectively).There is no significant relationship between medication adherence with average scores of cognitive de-fusion, fusion, specific necessity and beliefs about medication subscales (specific concern, general overuse and general harm)Discussion: In this study, we found medication adherence of patients with HPN was associated with their age and valued living. It means values-action consistency was correlated with medication adherence.