ARYA Atherosclerosis Journal

J wave syndrome: Benign or malignant?

Document Type : Review Article

Authors

Alborz Sherafati 1
Masoud Eslami 2
Reza Mollazadeh 2

1 Assistant Professor, Department of Cardiology, School of Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

2 Associate Professor, Department of Cardiology, School of Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

https://doi.org/10.22122/arya.v17i0.2259
Abstract
J wave syndrome is an electrical disease of the heart due to pathologic early repolarization. It encompasses a clinical spectrum from aborted sudden cardiac death due to ventricular arrhythmia (VA) usually in young affected patients to self-terminating ventricular ectopies, and finally, asymptomatic relatives of probands detected during electrocardiography acquisition (early repolarization pattern). This syndrome consists of 2 phenotypes, early repolarization and Brugada syndrome. Herein, we first describe 2 patients with early repolarization and Brugada syndrome, then, discuss their definition, epidemiology, genetics, cellular mechanism, diagnosis, risk stratification, and finally, therapeutic challenges and options one by one in detail.

Keywords

Brugada Syndrome
Sudden Cardiac Death
Ventricular Tachycardia
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ARYA Atherosclerosis Journal
Volume 17, Issue 1
January and February 2021
Pages 1-9

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