A case series of pulmonary hypertension in small infants with atrial septal defect

Sabri, Mohammad Reza; Mahdavi, Chehreh; Bigdelian, Hamid; Ahmadi, Ali Reza; Ghaderian, Mehdi; Dehghan, Bahar

doi:10.22122/arya.v16i4.2157

A case series of pulmonary hypertension in small infants with atrial septal defect

Document Type : Case Series

Authors

Mohammad Reza Sabri ¹

Chehreh Mahdavi ²

Hamid Bigdelian ³

Ali Reza Ahmadi ⁴

Mehdi Ghaderian ⁴

Bahar Dehghan ²

¹ Professor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

² Assistant Professor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

³ Associate Professor, Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

⁴ Associate Professor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

https://doi.org/10.22122/arya.v16i4.2157

Abstract

BACKGROUND: Atrial septal defect (ASD) is one of the most common congenital heart defects (CHDs) with prevalence of 8% to 10% in children with CHD and incidence of 56 per 100000 live births. It is categorized according to the defect site in which the most common form is secundum ASD (ASD2) with the defect in the central part of the atrial septum.CASE REPORT: In our case series, we evaluated five children aged under one year old with ASD2 and pulmonary hypertension (PH). All the patients were referred for surgical ASD closure. Their PH was improved and the size of right atrium (RA) and right ventricle (RV) became normal during the follow-up and one year after the surgery all of them had normal pulmonary artery pressure (PAP) with normal RA and RV size.CONCLUSION: According to our study and those done by others, the prevalence of PH in infants with ASD is low, but when this combination is found without any other CHD, ASD closure should be considered.

Keywords

Atrial Septal Defect

Pulmonary Hypertension

Congenital Heart Defects

Infant

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