ARYA Atherosclerosis Journal

The Relationship between serum vitamin D levels and ankle-brachial index in patients with metabolic syndrome

Document Type : Original Article(s)

Authors

Davoud Kazemisaleh 1
Keivan Kiani 2
Masoumeh Sadeghi 3
Hamidreza Roohafza 4
Minoo Dianatkhah 5
Nizal Sarrafzadegan 6

1 Associate Professor, Atherosclerosis Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

2 Resident, Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

3 Professor, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

4 Associate Professor, Psychosomatic Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

5 Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

6 Professor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

https://doi.org/10.22122/arya.v14i1.1664
Abstract
BACKGROUND: Vitamin D deficiency is a prevalent condition in Iran and previous studies have shown that a low level of serum vitamin D is related to low ankle-brachial index (ABI). In the present study, the relationship of the serum level of vitamin D with ABI, as an index for atherosclerosis of peripheral arteries, was evaluated.METHODS: In this cross-sectional study, data on 91 patients with metabolic syndrome (Mets) from the Isfahan Cohort Study (ICS) were analyzed in order to evaluate the association between serum 25(OH) vitamin D level and ABI. The participants were divided into two groups; group A with desirable serum vitamin D level and group B with abnormal serum vitamin D level. ABI was measured and compared between these groups.RESULTS: A crude and adjusted model showed no association between vitamin D level and ABI in patients with MetS.CONCLUSION: It can be concluded that serum vitamin D level could not affect ABI in patients with MetS.

Keywords

Vitamin D
Ankle Brachial Index
Metabolic Syndrome
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ARYA Atherosclerosis Journal
Volume 14, Issue 1 - Serial Number 1
January and February 2018
Pages 11-16

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