Document Type : Original Article(s)


1 Professor, Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Department of Internal Medicine, School of Medicine, Arash Hospital, Tehran University of Medical Sciences, Tehran, Iran

3 Assistant Professor, Inflammation and Inflammatory Diseases Research Center AND Department of Immunology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

4 State Health Center, Mashhad University of Medical Sciences, Mashhad, Iran

5 Assistant Professor, Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


BACKGROUND: Hypertension (HTN) is an important public health challenge worldwide. The prevalence of HTN varies across countries. It is necessary to obtain valid information about the prevalence of chronic condition like HTN and its predictors in different societies. Hence, this study was conducted to assess the prevalence of HTN and associated factors in Mashhad, Iran, 2015. METHODS: This cross-sectional study was performed on 2974 adults residing in Mashhad in 2015. Multistage random sampling was used. A checklist was fulfilled for each subject, and a blood sample was taken for measuring fasting blood sugar, total cholesterol, triglycerides, hemoglobin, serum creatinine, high-density lipoproteins, and low-density lipoproteins. The height and weight of participants and their blood pressure were measured according to protocols. RESULTS: The prevalence of HTN in this population was 22% (25.9% in male and 20% in female). Most interestingly, smoking and drug abuse were more prevalent in men (14.9% and 3.8%), but the sedentary behavior was more prevalent in women (51%). Interestingly, by increasing the age, the frequency of optimum, normal and high normal type was decreased and the frequency of HTN, specially sever form were increased. In binary logistic regression model, age [odds ratio (OR): 1.07, 95% confidence interval (CI): 1.06-1.09], gender (Ref:Female) (OR: 1.39, 95% CI: 1.05-1.83), and obesity (OR: 1.09, 95% CI: 1.06-1.12) were the predictors of HTN. CONCLUSION: The prevalence of HTN among this population was found to be high; which indicates the need for HTN-screening programs, especially for the elderly, male and obese population. Given the close relationship between obesity and various diseases, including HTN, practical solutions, including lifestyle interventions, need to be developed.   


  1. Mohan S, Campbell N, Chockalingam A. Time to effectively address hypertension in India. Indian J Med Res 2013; 137(4): 627-31.
  2. James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014; 311(5): 507-20.
  3. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360(9349): 1903-13.
  4. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289(19): 2560-72.
  5. Kearney PM, Whelton M, Reynolds K, Whelton PK, He J. Worldwide prevalence of hypertension: a systematic review. J Hypertens 2004; 22(1): 11-9.
  6. Haghdoost AA, Sadeghirad B, Rezazadehkermani M. Epidemiology and heterogeneity of hypertension in Iran: a systematic review. Arch Iran Med 2008; 11(4): 444-52.
  7. Veghari G, Sedaghat M, Maghsodlo S, Banihashem S, Moharloei P, Angizeh A, et al. Impact of Literacy on the Prevalence, Awareness, Treatment andControl of Hypertension in Iran. J Cardiovasc Thorac Res 2012; 4(2): 37-40.
  8. Sahraki R, Mirshekari M, Sahraki H, Mohammadi AR, Sahraki M, Khazaei Feizabad E. Hypertension Among 30+ Year-Old People in Zahedan (Southeast of Iran). Shiraz E Med J 2011; 12(3): 129-34.
  9. Namayandeh S, Sadr S, Rafiei M, Modares-Mosadegh M, Rajaefard M. Hypertension in Iranian urban population, epidemiology, awareness, treatment and control. Iran J Public Health 2011; 40(3): 63-70.
  10. Azizi F, Esmaillzadeh A, Mirmiran P. Obesity and cardiovascular disease risk factors in Tehran adults: a population-based study. East Mediterr Health J 2004; 10(6): 887-97.
  11. Peymani P, Heydari ST, Ahmadi SM, Lankarani KB. The prevalence of high blood pressure and its relationship with anthropometric indicators; a population based study in Fars Province, IR Iran. J Cardiovasc Thorac Res 2012; 6(2): 40-5.
  12. Esteghamati A, Meysamie A, Khalilzadeh O, Rashidi A, Haghazali M, Asgari F, et al. Third national Surveillance of Risk Factors of Non-Communicable Diseases (SuRFNCD-2007) in Iran: methods and results on prevalence of diabetes, hypertension, obesity, central obesity, and dyslipidemia. BMC Public Health 2009; 9: 167.
  13. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care
  14. ; 31(Suppl): S55-S60.
  15. Taylor RB. Family medicine: principles and practice. 5th ed. Berline, Germany: Springer Science & Business Media; 2013.
  16. Aronow WS, Fleg JL, Pepine CJ, Artinian NT, Bakris G, Brown AS, et al. ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus documents developed in collaboration with the American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologists, and European Society of Hypertension. J Am Coll Cardiol 2011; 57(20): 2037-114.
  17. Cheraghian B, Asadi-Lari M, Mansournia MA, Majdzadeh R, Mohammad K, Nedjat S, et al. Prevalence and associated factors of self-reported hypertension among Tehran adults in 2011: a population-based study (Urban HEART-2). Med J Islam Repub Iran 2014; 28: 105.
  18. Sarry El-Din A, Erfan M, Kandeel W, Kamal S, El Banna R, Fouad W. Prevalence of pre-hypertension and hypertension in a sample of egyptian adults and its relation to obesity. Aust J Basic Appl Sci 2012; 6(13): 481-9.
  19. Shapo L, Pomerleau J, McKee M. Epidemiology of hypertension and associated cardiovascular risk factors in a country in transition: a population based survey in Tirana City, Albania. J Epidemiol Community Health 2003; 57(9): 734-9.
  20. Manandhar K, Koju R, Sinha NP, Humagain S. Prevalence and associated risk factors of hypertension among people aged 50 years and more in Banepa Municipality, Nepal. Kathmandu Univ Med J (KUMJ) 2012; 10(39): 35-8.
  21. Azizi F, Ghanbarian A, Madjid M, Rahmani M. Distribution of blood pressure and prevalence of hypertension in Tehran adult population: Tehran Lipid and Glucose Study (TLGS), 1999-2000. J Hum Hypertens 2002; 16(5): 305-12.
  22. Gupta R. Trends in hypertension epidemiology in India. J Hum Hypertens 2004; 18(2): 73-8.
  23. Hatmi ZN, Tahvildari S, Gafarzadeh MA, Sabouri KA. Prevalence of coronary artery disease risk factors in Iran: a population based survey. BMC Cardiovasc Disord 2007; 7: 32.
  24. Dogan N, Toprak D, Demir S. Hypertension prevalence and risk factors among adult population
  25. in Afyonkarahisar region: a cross-sectional research. Anadolu Kardiyol Derg 2012; 12(1): 47-52.
  26. Colin BA, Adair LS, Popkin BM. Ethnic differences in the association between body mass index and hypertension. Am J Epidemiol 2002; 155(4): 346-53.
  27. Nielsen GA, Andersen LB. The association between high blood pressure, physical fitness, and body mass index in adolescents. Prev Med 2003; 36(2): 229-34.
  28. Guagnano MT, Ballone E, Pace-Palitti V, Vecchia RD, D'Orazio N, Manigrasso MR, et al. Risk factors for hypertension in obese women. The role of weight cycling. Eur J Clin Nutr 2000; 54(4): 356-60.
  29. Amirkhizi F, Siassi F, Minaie S, Jalali M, Dorosty Motlagh A R, Chamari M. Assessment of blood pressure status and its relationship with anthropometric indices among women in rural areas of Kerman province, Iran. Yafteh 2009; 10(2): 31-8.
  30. Primatesta P, Falaschetti E, Gupta S, Marmot MG, Poulter NR. Association between smoking and blood pressure: evidence from the health survey for England. Hypertension 2001; 37(2): 187-93.
  31. Beunza JJ, Martinez-Gonzalez MA, Ebrahim S, Bes-Rastrollo M, Nunez J, Martinez JA, et al. Sedentary behaviors and the risk of incident hypertension: the SUN Cohort. Am J Hypertens 2007; 20(11): 1156-62.
  32. Ordunez P, Munoz JL, Espinosa-Brito A, Silva LC, Cooper RS. Ethnicity, education, and blood pressure in Cuba. Am J Epidemiol 2005; 162(1): 49-56.
  33. Xu X, Niu T, Christiani DC, Weiss ST, Zhou Y, Chen C, et al. Environmental and occupational determinants of blood pressure in rural communities in China. Ann Epidemiol 1997; 7(2): 95-106.
  34. Gharipour M, Khosravi A, Sadeghi M, Roohafza H, Hashemi M, Sarrafzadegan N. Socioeconomic characteristics and controlled hypertension: Evidence from Isfahan Healthy Heart Program. ARYA Atheroscler 2013; 9(1): 77-81.
  35. Dadgarmoghaddam M, Khajedaluee M, Khadem Rezaiyan M, Khodaee G. Risk factors for non-communicable disease: a population based study in Mashhad (Iran). Br J Med Med Res 2015; 7(6): 503-11.