Document Type : Original Article(s)


1 Assistant Professor, Department of Mental Health, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

2 Assistant Professor, Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran

3 Professor, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

4 PhD Fellow, Department of Endocrinology and Diabetes, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark

5 Assistant Professor, Mental Health Research Center, Tehran Institute of Psychiatry AND School of Behavioral Sciences and Mental Health, Iran University of Medical Sciences, Tehran, Iran

6 Associate Professor, Department of Biostatistics, School of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

7 Professor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran


BACKGROUND: We have assessed the role of stress on compliance of patients with diabetes mellitus (DM) and hypertension (HTN) with taking prescribed medications and following dietary and exercise regimens. METHODS: A total of 9544 individuals more than 19 years of age were selected from three counties in central Iran. The presence of DM and HTN were asked from participants. We defined treatment adherence (compliance) based on agreement of individual’s self-report behavior with recommendations from a physician. RESULTS: Awareness about DM and HTN was 82.6% and 49.9%, respectively. Multivariate analysis showed that odds ratio (OR) of high to low stress level was lower than one for both “usage of medication” and “following exercise regimen” in diabetics even after adjustment for either “age and sex” or “age, sex and education”. In hypertensive patients, OR of high to low stress level was lower than one for “usage of medication” even after adjustment for either “age and sex” or “age, sex and education” and also lower than one for “following exercise regimen” only as crude index. CONCLUSION: Cases with higher stress level had lower compliance for accepting either medication or exercise as a treatment option for their DM or HTN. 


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