ARYA Atherosclerosis Journal

Prognostic factors of 28 days survival rate in patients with a first acute myocardial ‎infarction based on gender in Isfahan, Iran (2000-2009)‎

Document Type : Original Article(s)

Authors

Mahdi Mohammadian 1
Shidokht Hosseini 2
Hamid Salehiniya 3
Masoumeh Sadeghi 4
Nizal Sarrafzadegan 5
Hamid‏ ‏Reza Roohafza 6
Salman Khazaei 7
Shahin Soltani 8
Ali Sarrafkia 9
Jafar Golshahi 10
Abdollah Mohammadian-Hafshejani ‎ 11

1 Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan ‎University of Medical Sciences, Isfahan, Iran

2 Researcher, Hypertension Research Center, Cardiovascular Research Institute, Isfahan ‎University of Medical Sciences, Isfahan, Iran

3 Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran AND ‎Phd Candidate, Department of Epidemiology and Biostatistics, School of Public Health, Tehran ‎University of Medical Sciences, Tehran, Iran

4 Associate Professor, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, ‎Isfahan University of Medical Sciences, Isfahan, Iran

5 Professor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan ‎University of Medical Sciences, Isfahan, Iran

6 Assistant Professor, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, ‎Isfahan University of Medical Sciences, Isfahan, Iran

7 PhD Candidate, Department of Epidemiology and Biostatistics, School of Public Health, Hamadan ‎University of Medical Sciences, Hamadan, Iran

8 Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

9 Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of ‎Medical Sciences, Tehran, Iran‎

10 Associate Professor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, ‎Isfahan, Iran

11 Epidemiologist, Department of Social Medicine, School of Medicine, Rafsanjan University of ‎Medical Sciences, Rafsanjan AND Phd Candidate, Department of Epidemiology and Biostatistics, ‎School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Abstract
BACKGROUND: Determinant prognostic factors of 28 days survival rate in patients with a first acute myocardial infarction (AMI) based on gender in teen year’s period in Isfahan, Iran, was the aim of this study. METHODS: This study is a prospective hospital-based study that consisted, all patients with AMI admitted to all hospitals (private and universal hospitals) in Isfahan and Najafabad (Iran) during 2000-2009. To determinant the prognostic factors of 28 days survival rate in patients based on gender, analysis conducted separately for male and female. In analysis, we use of t-test, log Rank tests, Kaplan-Meier method, and univariate and multivariate Cox regression model. FINDINGS: Short-term (28 days) survival rate was 92.5% in male and 86.7% in female (P < 0.001). The adjusted hazard ratio (HR) of death for age group 80 years and older was 12.7 [95% confidence interval (CI): 5.14-31.3] in male and 8.78 (95% CI: 1.2-63.1) in female. HR for acute transmural MI of the unspecified site in male was 8.9 (95% CI: 4.68-16.97) and in female 9.33 (95% CI: 4.42-19.7). HR for receive of streptokinase in male was 1.11 (95% CI: 0.94-1.31) and in female was 0.69 (95% CI: 0.56-0.84). CONCLUSION: Short-term survival rate in male was a higher than female. In male age, anatomic location of MI and hospital status and in female streptokinase use and anatomic location of MI was the most important prognostic factors of survival in-patient with AMI in Isfahan.

Keywords

Myocardial Infarction
Survival Rate
Gender
Isfahan (Iran)‎
ARYA Atherosclerosis Journal
Volume 11, Issue 6 - Serial Number 6
November and December 2015
Pages 332-340

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