BACKGROUND: Myocardial infarction is a common and lethal disease, especially in the firsthours. Rapid and correct decision is essential to prioritize advanced therapies. This studyfollowed the accuracy of a scoring system for this triage. The aim was to assess the correlationbetween thrombolysis in myocardial infarction risk scores and angiographic scores in patientswith ST elevation myocardial infarctio.METHODS: In this cross-sectional, correlation study, 240 patients with ST elevationmyocardial infarction from coronary care units (CCUs) of 3 academic hospitals in Isfahan, Iran,were evaluated. Thrombolysis in myocardial infarction risk score was calculated. All subjectsunderwent angiography and were followed up for 2 months.RESULTS: Mean age of patients was 60.02 ± 11.95 years old and 79 patients were female. Thecorrelation between thrombolysis in myocardial infarction risk and angiographic scores wassignificant (P < 0.001). In addition, the correlations between ejection fraction and thrombolysisin myocardial infarction risk score (P < 0.001), as well as angiographic score and age (P < 0.001)were significant. There was no significant correlation between angiographic score and recurrentangina (P = 0.143), rehospitalization (P = 0.524), and death (P = 0.179). Pearson's correlationshowed a significant relation between thrombolysis in myocardial infarction risk score andangiographic score (P < 0.001; r = 0.556).CONCLUSION: This study showed that thrombolysis in myocardial infarction risk score couldprobably be used for evaluating the angiographic extent of coronary artery disease. If confirmedby a prospective cohort study, simple clinical use of this score at bedside would make it amethod to stratify patients in high and low risk groups. Diagnostic and therapeutic strategieswould accordingly be catgorized.Keywords: Thrombolysis in Myocardial Infarction Risk Score, Angiographic Score, ST ElevationMyocardial Infarction, Ejection Fraction.