Document Type : Original Article(s)

Authors

• Mostafa Cheraghi ¹
• Masoumeh Sadeghi ²
• Aliakbar Tavassoli ³
• Nizal Sarrafzadegan ⁴
• Ali Pourmoghadas ⁵
• Mohammad Arash Ramezani ⁶

¹ Cardiology Fellow, Isfahan University of Medical Sciences, Isfahan, Iran.

² Associate Professor of cardiology,Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical sciences, Isfahan ,Iran.

³ Associate Professor of Cardiology, Isfahan School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

⁴ Professor of Cardiology, Isfahan Cardiovascular Research Institute, Isfahan University of Medical sciences, Isfahan ,Iran.

⁵ Associate Professor of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

⁶ Community Medicine Specialist, Isfahan Cardiovascular Research Center, Isfahan, Iran.

Abstract

Abstract:BACKGROUND: The prevalence of Congestive Heart Failure (CHF) is increasing in recent years. Factors associated with mortality in CHF patients are important to be determined in order to select therapeutic modality by physicians. The purpose of the current study was to declare predictors of 6-months survival in patients hospitalized for decompensated CHF in Isfahan.METHODS: A cohort of 301 hospitalized patients with decompensated CHF were recruited in this study. The diagnosis of CHF was based on previous hospitalizations and Framingham criteria for heart failure (HF). Information regarding past history, accompanying diseases such as cerebrovascular accidents (CVA), chronic obstructive pulmonary diseases (COPD), clinical data, medications and echocardiography were obtained by a cardiologist. Patients were followed for their survival for 6 months by telephone calls. Kaplan-Meier method was used for uni variate survival analysis and Cox proportional hazard model was used for multivariate analysis.RESULTS: Mean age of patients was 71.9 ± 12.2 years and 59.8% was male. During 6-months follow-up 138 (45.8%) patients died. Mean survival was 119.2 ± 4.4 days (Mean ± SEM). Significant prognostic factors for 6 months survival were high education level (HR = 0.74, CI 95% 0.59—0.93), COPD (HR = 1.91, CI 95% 1.2—3.04), CVA (HR = 1.69, CI 95% 1.03—2.78), Angiotensin Converting enzyme (ACE) inhibitors use (HR = 0.44, CI 95% 0.3—0.66) and Diuretics (HR = 0.63, CI 95% 0.41-0.96).CONCLUSION: Six-month survival of hospitalized decompensated CHF patients in Iran is not favorable. Many factors particularly accompanying diseases and medications affected the patient’s 6-months survival.Keywords: Heart failure, Survival,  Mortality.