Document Type : Original Article(s)


1 Research Management Department, Isfahan Cardiovascular Research Center

2 MD,

3 MD


AbstractINTRODUCTION: The clustering of several cardiovascular disease risk factors such asabdominal obesity, hypertension, dyslipidemia and disturbances in glucose metabolism hasbeen termed the Metabolic Syndrome (MS). The MS has been shown to predictcardiovascular disease (CVD) and diabetes. Epidemiological studies have demonstratedthat CVD is the main cause of worldwide mortality; they have also linked diabetes to anincreased risk of mortality due to CVD.METHODS: According to the ATP III (Adult Treatment Panel) reports, individuals havingthree or more of the following criteria are defined as having the MS: abdominal obesity(waist circumference > 102 cm in men and >88 cm in woman), hypertriglyceridemia(triglyceride ≥ 150 mg/dl), low high-density lipoprotein (HDL) cholesterol (HDL<40 mg/dl inmen and <50 mg/dl in women), high fasting blood sugar (FBS) (FBS≥110 mg/dl) and highblood pressure (BP) (BP≥130/85 mmHg). The SPSS package (SPSS Chicago IL) was usedand the significance level was set at P<0.05.RESULTS: Overall, the age-adjusted prevalence of the MS was 25.4% and 21.7% in theurban and rural areas of Isfahan, respectively. It was the highest among 50-59-year-old ruralIsfahani women (68.9%) and the lowest among rural Araki men (5.6%).DISCUSSION: We found approximately 21.9% of Iranian adults living in Central Iran tohave the MS. In summary, this study showed an increasing risk of the MS among middleagedwoman in urban areas owing to their physical quality of life. The results indicate thatprimary prevention should not only consider biological risk factors, but also take account ofsociodemographic variables to identify individuals at high risk for diabetes andcardiovascular disease.Keywords • Metabolic syndrome • ATPIII • Prevalence • Iran