Document Type : Original Article(s)


1 MD

2 MD, Associate Professor of Pediatrics, Isfahan Metabolism and Endocrinology Research Cente.

3 MD, Associate Professor, Preventive Pediatric Cardiology Department, Isfahan Cardiovascular Research Center.


AbstractINTRODUCTION: Diabetes mellitus in the most common endocrine-metabolic diseasein children and is associated with cardiovascular disease risk factors. This study aimed tocompare the lipid profile of diabetic children with controls.METHODS: In this case-control study, the lipid profiles and lipoprotein levels of 45children aged 2-18 years with established diabetes were compared with those of 45healthy controls.RESULTS: Mean apolipoprotein A and triglyceride levels in the cases were higher inthan in controls, while mean apolipoprotein B and lipoprotein a, as well as total, LDL andHDL cholesterol were higher in controls.CONCLUSIONS: Better apolipoprotein levels and lipid profiles in diabetic children ascompared to controls were likely due to tight nutritional control in diabetic patientsunder study.Key Words: Diabetes mellitus, lipid profile, apolipoproteins, children.