Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
01
Combination of atorvastatin/coenzyme Q10 as adjunctive treatment in congestive heart failure: A double-blind randomized placebo-controlled clinical trial
1
5
10388
EN
Masoud
Pourmoghaddas
Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Majid
Rabbani
Resident, Hypertension Research Center, Isfahan Cardiovascular Research Institute , Isfahan University of Medical Sciences, Isfahan, Iran
Javad
Shahabi
Resident, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0001-6902-2150
Mohammad
Garakyaraghi
Associate Professor, Heart Failure Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Reza
Khanjani
Resident, Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Pegah
Hedayat
Resident, Department of Pathology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
06
23
BACKGROUND: Heart failure is one of the leading causes of mortality, is a final common pathway of several cardiovascular diseases, and its treatment is a major concern in the science of cardiology. The aim of the present study was to compare the effect of addition of the coenzyme Q10 (CoQ10)/atorvastatin combination to standard congestive heart failure (CHF) treatment versus addition of atorvastatin alone on CHF outcomes. METHODS: This study was a double-blind, randomized placebo-controlled trial. In the present study, 62 eligible patients were enrolled and randomized into 2 groups. In the intervention group patients received 10 mg atorvastatin daily plus 100 mg CoQ10 pearl supplement twice daily, and in the placebo group patients received 10 mg atorvastatin daily and the placebo of CoQ10 pearl for 4 months. For all patients echocardiography was performed and blood sample was obtained for determination of N-terminal B-type natriuretic peptide, total cholesterol, low density lipoprotein, erythrocyte sedimentation rate, and C-reactive protein levels. Echocardiography and laboratory test were repeated after 4 months. The New York Heart Association Function Class (NYHA FC) was also determined for each patient before and after the study period. RESULTS: Data analyses showed that ejection fraction (EF) and NYHA FC changes differ significantly between intervention and placebo group (P = 0.006 and P = 0.002, respectively). Changes in other parameters did not differ significantly between study groups. CONCLUSION: We deduce that combination of atorvastatin and CoQ10, as an adjunctive treatment of CHF, increase EF and improve NYHA FC in comparison with use of atorvastatin alone. Keywords: Coenzyme Q10, Atorvastatin, Clinical Trial, Congestive Heart Failure
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
14
Comparison of competing risks models based on cumulative incidence function in analyzing time to cardiovascular diseases
6
12
10398
EN
Minoo
Dianatkhah
Department of Statistics and Computer Sciences, University of Social Welfare and Rehabilitation Sciences, Tehran AND Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0001-8092-2045
Mehdi
Rahgozar
Assistant Professor, Department of Statistics and Computer Sciences, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
Mohammad
Talaei
Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran AND Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore
Masoud
Karimloua
Assistant Professor, Department of Statistics and Computer Sciences, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
Masoumeh
Sadeghi
Associate Professor, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0001-7179-5558
Shahram
Oveisgharan
Department of Neurology, Tehran University of Medical Sciences, Tehran, Iran
Nizal
Sarrafzadegan
Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
07
28
BACKGROUND: Competing risks arise when the subject is exposed to more than one cause of failure. Data consists of the time that the subject failed and an indicator of which risk caused the subject to fail. METHODS: With three approaches consisting of Fine and Gray, binomial, and pseudo-value, all of which are directly based on cumulative incidence function, cardiovascular disease data of the Isfahan Cohort Study were analyzed. Validity of proportionality assumption for these approaches is the basis for selecting appropriate models. Such as for the Fine and Gray model, establishing proportionality assumption is necessary. In the binomial approach, a parametric, non-parametric, or semi-parametric model was offered according to validity of assumption. However, pseudo-value approaches do not need to establish proportionality. RESULTS: Following fitting the models to data, slight differences in parameters and variances estimates were seen among models. This showed that semi-parametric multiplicative model and the two models based on pseudo-value approach could be used for fitting this kind of data. CONCLUSION: We would recommend considering the use of competing risk models instead of normal survival methods when subjects are exposed to more than one cause of failure. Keywords: Competing Risks, Cumulative Incidence Function, Fine and Gray Model, Binomial Approach, Pseudo-value Approach, Cardiovascular Diseases
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
16
Atrioventricular block as the initial presentation of calcified bicuspid aortic valve
59
64
10397
EN
Reza
Karbasi-Afshar
Department of Cardiovascular Diseases, School of Medicine AND Atherosclerosis Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
Nematollah
Jonaidi-Jafari
Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
Amin
Saburi
Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
Arezoo
Khosravi
Assistant Professor, Department of Cardiovascular Diseases, School of Medicine AND Atherosclerosis Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
Journal Article
2012
12
30
BACKGROUND: Bicuspid aortic valve (BAV) is one of the most common and important congenital heart disorders in adults. If a patient with congenital disorders is not diagnosed early, the patient’s disease may progress to a severe condition and thus diagnosis of the main disorder will be rendered difficult. CASE REPORT: A 34 year-old male patient referred to a referral medical care unit for cardiac electrophysiological study with cardiac shock due to complete heart block 3 months ago and he underwent Dual-Chamber permanent pacemaker (PPM) implantation. Thick and calcified bicuspid AV with invasion to interventricular septum, moderate to severe valve insufficiency (AI), severe aortic valve stenosis (AS), and dilated ascending aorta were observed at his echocardiography. Aortic valve replacement (AVR), aneurysm of ascending aorta, root replacement with tube graft (Bentall Procedure), and also a 3 chambers intracardiac defibrillator (ICD) were used. After 2 weeks of operation, he was discharged and at the first post-hospitalization visit (1 week later), his cardiovascular condition was acceptable. CONCLUSION: Thick calcified aortic root is a less studied and potential contributing risk factor for AV block after AVR. Therefore, in candidates of aortic valve replacement, considering conductive disorders, especially in patients with calcified valve, is mandatory. Irreversible AV block requiring PPM implantation is a rare condition following AVR. Keywords: Atrioventricular Block, Bicuspid Aortic Valve, Calcified Valve
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
14
Stent underexpansion in angiographic guided percutaneous coronary intervention, despite adjunctive balloon post-dilatation, in drug eluting stent era
13
17
10389
EN
Mehrdad
Taherioun
Cardiac Rehabilitation Research Centre, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Mohammad Hassan
Namazi
Associate Professor, Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Morteza
Safi
Associate Professor, Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Habibolah
Saadat
Professor, Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Hossein
Vakili
Associate Professor, Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Saeed
Alipour-Parsa
Assistant Professor, Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Hasan
Rajabi-Moghadam
Assistant Professor, Kashan University of Medical Sciences, Kashan, Iran
Shamsedin
Pedari
Cardiac Rehabilitation Research Centre, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
05
16
BACKGROUND: Stent underexpansion is the most powerful predictor of long-term stent patency and clinical outcome. The purpose of this study was to evaluate the incidence and predictors of stent underexpansion despite adjunctive post-dilatation with non-compliant balloon. METHODS: After elective coronary stent implantation and adjunctive post-dilatation with non-compliant balloon and optimal angiographic result confirmed by the operator, intravascular ultrasound (IVUS) was performed for all the treated lesions. If the treated lesions fulfilled the IVUS criteria, they are considered as the optimal stent group; if not, they are considered as the suboptimal group. RESULTS: From 50 patients enrolled in this study 39 (78%) had optimal stent deployment and 11 (22%) had suboptimal stent deployment. In the suboptimal group 7 (14%) had underexpansion, 2 (4%) malposition, and 2 (4%) had asymmetry. There were no stent edge dissections detected by IVUS. We did not find any correlation between lesion calcification, ostial lesions, stent length, and stent underexpansion. Stent diameter ≤ 2.75 mm had a strong correlation with stent underexpansion. CONCLUSION: Despite adjunctive post-dilatation with noncompliant balloon, using a relatively small stent diameter was a strong predictor for underexpansion. IVUS guided percutaneous coronary intervention (PCI) may be considered for drug eluting stent (DES) implantation in relatively small vessels. Keywords: Stent, Percutaneous Coronary Intervention, Ultrasound, Post-dilatation
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
14
Relationship between legumes consumption and metabolic syndrome: Findings of the Isfahan Healthy Heart Program
18
24
10390
EN
Firouzeh
Sajjadi
Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Mojgan
Gharipour
PhD Candidate, Department of Metabolic Syndrome, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0002-0375-4874
Noushin
Mohammadifard
PhD Candidate, Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0003-1776-1060
Fatemeh
Nouri
Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences,
Isfahan, Iran
Maryam
Maghroun
Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Hasan
Alikhasi
Department of Nutrition, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
07
23
BACKGROUND: Epidemiologic studies have shown an inverse association between dietary fiber and metabolic syndrome (MetS). Therefore, the purpose of this study was to investigate the association between MetS and consumption of legumes in adults in Isfahan, Iran. METHODS: This cross-sectional study was carried out on 2027 individuals who were a subsample of the 3rd phase of the Isfahan Healthy Heart Program (IHHP). Basic characteristics information such as age, sex, smoking status, and physical activity were collected using a questionnaire. A validated 48-item food frequency questionnaire was used to assess dietary behaviors. Blood pressure, waist circumference (WC), glucose, triacylglycerols, and high-density lipoprotein cholesterol were measured, and MetS was defined based on Adult Treatment Panel III guidelines. Multiple logistic regression models examined associations of frequency consumption of legumes with MetS occurrence and its components. RESULTS: All MetS components were less prevalent among subjects with regular legume intake (P < 0.01). Legume intake was inversely associated with the risk of MetS, after adjustment for confounding factors in women. Life style adjusted odds ratio of Mets between highest and lowest tertile and no consumption (as reference category) of legume intake were 0.31 (0.13, 0.70), 0.38 (0.17, 0.87), respectively, in women (P = 0.01). CONCLUSION: This study showed that age has a crucial role in MetS incidence; therefore, after further age adjustment to lifestyle adjusted model there was no significant difference in lower and higher tertile of legume intake and MetS. Keywords: Legumes, Metabolic Syndrome, Iran
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
14
Determinants of uncontrolled hypertension in an Iranian population
25
31
10391
EN
Somayeh
Arabzadeh
Resident, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Masoumeh
Sadeghi
Associate Professor, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0001-7179-5558
Katayoun
Rabiei
Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Nizal
Sarrafzadegan
Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Ladan
Taheri
Resident, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Jafar
Golshahi
Associate Professor, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
09
01
BACKGROUND: Uncontrolled hypertension, a major concern among hypertensive patients, may be caused by various factors such as inadequate knowledge and inappropriate attitude, unhealthy lifestyle, and ineffective treatment. The present study tried to cast light on factors leading to uncontrolled hypertension. METHODS: In this cross-sectional study, all hypertensive participants of the third phase of the Isfahan Healthy Heart Program were contacted and invited to take part in the study. A questionnaire including knowledge of and attitude toward hypertension and its control and treatment methods, and practice about lifestyle and pharmacological treatment was completed for all patients who consented to participate. The participants’ anthropometric indices and blood pressure were then measured. Chi-square and Student’s t-tests were used to compare the groups with controlled and uncontrolled blood pressure. The effect of each factor on uncontrolled blood pressure was assessed by employing stepwise logistic regression. RESULTS: Of 114 participants, 43 (37.12%) and 71 (62.28%) individuals had controlled and uncontrolled blood pressure, respectively. Stepwise logistic regression revealed body mass index > 25 kg/m2 to have the greatest effects on uncontrolled blood pressure [Odds ratio (OR) = 13.091, Confidence interval of 95% (95% CI): 1.437-116.352, P = 0.021). In addition, male gender increased the risk for uncontrolled blood pressure (OR = 8.475, CI95%: 1.276-56.313, P = 0.027), while inappropriate attitude decreased the mentioned risk (OR = 0.047, CI95%: 0.007-0.318, P = 0.002). CONCLUSION: According to our findings, obesity is the most important cause of uncontrolled blood pressure. Therefore, weight has to be closely monitored and controlled in hypertensive patients. Keywords: Uncontrolled Hypertension, Obesity, Attitude
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
14
The relation between body iron store and ferritin, and coronary artery disease
32
36
10392
EN
Ali
Pourmoghaddas
Associate Professor, Cardiac Rehabilitation Research Center AND Heart Failure Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Hamid
Sanei
Associate Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Mohammad
Garakyaraghi
Heart Failure Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Fatemeh
Esteki-Ghashghaei
PhD Candidate, Isfahan Neurosciences Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Maryam
Gharaati
Chamran Heart Center, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
11
04
BACKGROUND: Iron is essential for many physiological processes; whereas, iron overload has been known as a risk factor in progression of atherosclerosis. The aim of this study was to investigate the importance of serum ferritin levels, which are known as an indicator of body iron stored in the incidence of coronary artery disease (CAD). METHODS: In a case-control study, we evaluated 432 eligible men who underwent coronary angiography at Chamran Cardiology Hospital, Isfahan, Iran. They were separated into two groups of case (with CAD) and control (without CAD). All subjects had given written informed consents. Then, the blood samples were taken after 12-14 hours of fast by a biologist for measuring cardiovascular risk factors and body iron stores, including serum ferritin, serum iron, and total iron binding capacity (TIBC). For statistical analyses, chi-square test, Student’s t-test, one-way ANOVA, and the logistic regression were used. RESULTS: In the present study, 212 participants with CAD in the case group and 220 participants free of CAD in the control group were included in the analysis. At baseline, there were significant differences in serum ferritin (P < 0.001) and other cardiovascular risk factors between the two groups. Moreover, when other risk factors of CVD were included in the model, serum ferritin [Odd Ratio (OR) = 1.006, 95% confidence interval of 95% (95% CI) 1.00-1.01, P = 0.045] and serum ferritin ≥ 200 (OR = 4.49, 95% CI 1.72-11.70, P < 0.001) were associated with CAD. CONCLUSION: High iron store, as assessed by serum ferritin, was associated with the increased risk of CAD. Furthermore, it was a strong and independent risk factor in the incident of atherosclerosis in the Iranian male population. Keywords: Iron, Ferritin, Coronary Artery Disease, Coronary Angiography
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
14
Comparison of cost-effectiveness and postoperative outcome of device closure and open surgery closure techniques for treatment of patent ductus arteriosus
37
40
10393
EN
Alireza
Ahmadi
Assistant Professor, Isfahan Cardiovascular Research Centre, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0002-0468-4126
Mohammadreza
Sabri
Professor, Department of Pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Hamid
Bigdelian
Assistant Professor, Division of Cardiovascular Surgery , Department of Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Bahar
Dehghan
Fellow of Pediatric Cardiology, Department of Pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0002-1302-8825
Mojgan
Gharipour
PhD Candidate, Cardiac Rehabilitation Research Centre, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0002-0375-4874
Journal Article
2013
11
09
BACKGROUND: Various devices have been recently employed for percutaneous closure of the patent ductus arteriosus (PDA). Although the high effectiveness of device closure techniques has been clearly determined, a few studies have focused on the cost-effectiveness and also postoperative complications of these procedures in comparison with open surgery. The present study aimed to evaluate the clinical outcome and cost-effectiveness of PDA occlusion by Amplatzer and coil device in comparisong with open surgery. METHODS: In this cross-sectional study, a randomized sample of 201 patients aged 1 month to 16 years (105 patients with device closure and 96 patients with surgical closure) was selected. The ratio of total pulmonary blood flow to total systemic blood flow, the Qp/Qs ratio, was measured using a pulmonary artery catheter. The cost analysis included direct medical care costs associated with device implantation and open surgery, as well as professional fees. All costs were calculated in Iranian Rials and then converted to US dollars. RESULTS: There was no statistical difference in mean Qp/Qs ratio before the procedure between the device closure group and the open surgery group (2.1 ± 0.7 versus 1.7 ± 0.6, P = 0.090). The mean measured costs were overall higher in the device closure group than in open closure group (948.87 ± 548.76 US$ versus 743.70 ± 696.91 US$, P < 0.001). This difference remained significant after adjustment for age and gender (Standardized Beta = 0.160, P = 0.031). PDA closure with the Amplatzer ductal occluder (1053.05 ± 525.73 US$) or with Nit-Occlud coils (PFM) (912.73 ± 565.94 US$, P < 0.001) was more expensive than that via open surgery. However, the Cook detachable spring coils device closure (605.65 ± 194.62 US$, P = 0.650) had a non-significant cost difference with open surgery. No event was observed in the device closure group regarding in-hospital mortality or morbidity; however, in another group, 2 in-hospital deaths occurred, two patients experienced pneumonia and seizure, and one suffered electrolyte abnormalities including hyponatremia and hypocalcemia. CONCLUSION: Although open surgery seems to be less expensive than device closure technique, because of lower mortality and morbidity, the latter group is more preferable. Keywords: Cost-effectiveness, Outcome, Device Closure, Open Surgery Closure, Patent Ductus Arteriosus
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
14
Does percutaneous nephrolithotomy cause elevated cardiac troponins?
41
45
10394
EN
Hassan
Shemirani
Associate Professor, Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0002-8977-6360
Reza
Khanjani
Department of Internal Medicine AND Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Mehrdad
Mohammadi-Sichani
Assistant Professor, Department of Urology AND Urology and Kidney Transplantation Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Sarah
Mozafarpour
Medical Student Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Majid
Rabbani
Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Javad
Shahabi
Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2012
10
28
BACKGROUND: Percutaneous nephrolithotomy is the treatment of choice in large and staghorn renal stones, and myocardial infarction is one the possible complications during and after the surgery. We investigated if renal and skeletal muscle injury, caused by percutaneous nephrolithotomy, can cause elevation in cardiac troponins (cTn). METHODS: This study was conducted on otherwise healthy patients with renal stone undergoing percutaneous nephrolithotomy. A baseline 12-lead electrocardiogram, echocardiography, and cTn assessment confirmed no cardiac pathology in any patients. Cardiac troponins T (cTnT) and I (cTnI), and also creatine kinase (CK) were assessed before and after surgery. RESULTS: A total of 55 patients (69.1% males, mean age: 40.5 ± 13.8 year) were included. Serum creatinine level ranged from 0.7 to 1.3 mg/dl (mean = 1.03 ± 0.17). The level of CK was significantly increased by 469.5 ± 201.4 U/l (P < 0.001), and no positive cTnT or cTnI was observed after surgery. CONCLUSION: The results of the present study showed that renal cell injury, caused by percutaneous nephrolithotomy, is not associated with elevated cardiac troponins. These findings show that increasing troponins in patients undergoing percutaneous nephrolithotomy indicate a cardiovascular pathology. Keywords: Percutaneous Nephrolithotomy, Coronary Artery Disease, Acute Coronary Syndrome, Cardiac Markers, Troponin
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
15
Seasonal pattern in admissions and mortality from acute myocardial infarction in elderly patients in Isfahan, Iran
46
54
10395
EN
Abdollah
Mohammadian-Hafshejani
Deputy of Health, Isfahan University of Medical Sciences, Isfahan AND PhD Candidates, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Nizal
Sarrafzadegan
Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Shidokht
Hosseini
Researcher, Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Hamid Reza
Baradaran
Associate Professor, Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
Hamidreza
Roohafza
Assistant Professor, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0003-3582-0431
Masoumeh
Sadeghi
Associate Professor, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0001-7179-5558
Mohsen
Asadi-Lari
Associate Professor, Department of Epidemiology, School of Health AND Oncopathology Research Center, Iran University of Medical Sciences, Tehran, Iran
Journal Article
2013
03
11
BACKGROUND: Seasonal variation in admissions and mortality due to acute myocardial infarction has been observed in different countries. Since there are scarce reports about this variation in Iran, this study was carried out to determine the existence of seasonal rhythms in hospital admissions for acute myocardial infarction, and in mortality due to acute myocardial infarction (AMI) in elderly patients in Isfahan city. METHODS: This prospective hospital-based study included a total of 3990 consecutive patients with acute myocardial infarction admitted to 13 hospitals from January 2002 to December 2007. Seasonal variations were analyzed with the Kaplan-Meier table, log rank test, and Cox regression model. RESULTS: There was a statistically significant relationship between the occurrence of heart disease based on season and type of acute myocardial infarction anatomical (P < 0.001). The relationship between the occurrence of death and season and type of AMI according to International Classification of Diseases code 10 (ICD) was also observed and it was statistically significant (P = 0.026). Hazard ratio for death from acute myocardial infarction were 0.96 [Confidence interval of 95% (95% CI) = 0.78-1.18], 0.9 (95%CI = 0.73-1.11), and 1.04 (95%CI = 0.85-1.26) during spring, summer, and winter, respectively. CONCLUSION: There is seasonal variation in hospital admission and mortality due to AMI; however, after adjusting in the model only gender and age were significant predictor factors. Keywords: Acute Myocardial Infarction, Season, Admission in Hospital, Mortality, Isfahan
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
14
Safety of herbal medicine for weight loss
55
58
10396
EN
Jamshid
Najafian
Assistant Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0002-1472-1218
Morteza
Abdar-Esfahani
Associate Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Morteza
Arab-Momeni
Resident, Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Afshan
Akhavan-Tabib
Researcher Assistant, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
11
07
BACKGROUND: Obesity is a common health problem in both developed and developing countries. There are many unconventional therapies, including herbal medicine, to treat this condition. Some people believe that herbal medicines are safe. This case and review is about adverse complication of treating obesity with some herbal medicine. CASE REPORT: A 19 year old male with sever obesity (120 kg) used green tea (15 cups of green tea per day) and an intensive dietary regimen to lose weight. He lost 30 kg after 2 months. At that time, one day after usual exercise he suddenly lost consciousness due to left ventricular fibrillation. CONCLUSION: Use of herbal medicine for weight reduction is not always safe. Moreover, for some herbal medicine the risk is sufficient to shift the risk–benefit balance against the use that medicine. Keywords: Herbal Medicine, Sudden Death, Complication, Obesity
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
01
The concept of Maslow's pyramid for cardiovascular health and its impact on “change cycle”
65
69
10399
EN
Mohaddeseh
Behjati
Isfahan Cardiovascular Research Center AND Heart Failure Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
07
09
Since the leading cause of morbidity and mortality is cardiovascular diseases, every individual should think regularly about possessing and maintaining cardiovascular health. In reality, this self-processing is delayed until the occurrence of complications related to cardiovascular inefficiency manifested as chest pain and/or dyspnea. However, people should be trained to think about their cardiovascular health issues as a vital need from early childhood. This goal is achievable by understanding it as a "true human derive" and its consecutive "behaviors". Most people are unaware of their real needs, and even if they know all of their cardiovascular needs, this knowledge is not projected in their behaviors. In the present paper, I try to outline the Herzberg two-factor hypothesis and Maslow's hierarchy of needs. Keywords: Maslow's Pyramid, Change Cycle, Cardiovascular Health
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
10
1
2014
01
01
Journal Index
10387
EN
Index
Journal
0000-0002-1825-0097
Journal Article
2014
04
14
Click to download the index of this issue