Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
13
Heart rate recovery in exercise test in diabetic patients with and without microalbuminuria
167
171
10348
EN
Ali
Pourmoghaddas
Associate Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Adrineh
Moghaddasian
Resident, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Mohammad
Garakyaraghi
Associate Professor, Hypertension Research Canter, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Negin
Nezarat
Cardiologist, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Ali
Mehrabi
Epidemiologist, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2012
06
21
BACKGROUND: Diabetes mellitus (DM) has a lot of complications such as macrovessel and microvessel disease. Another complication of DM is cardiac autonomic neuropathy (CAN), which have effect on automatic nervous system of heart. Failure in heart rate slowing after exercise is a presentation of this abnormality.METHODS: We selected diabetic patients and divided them to case and control group based on microalbuminuria. Case group comprised of diabetic patients with microalbuminuria and control group included those without microalbuminuria. Patients in both groups exercised on treadmill using Bruce protocol and heart rate was measured in first and second minutes in the recovery period. RESULTS: We selected 35 patients with microalbuminuria (case group) and 35 without microalbuminuria (control group) among diabetic patients. No statistically significant difference was seen in sex and age between case and control groups. Heart rate recovery in the first minute of recovery in the case and control groups did not show significant difference; but in the second minute of recovery, it was significantly higher in control group (97 ± 19.4 vs. 101.9 ± 12.4 beat per minute, P = 0.04). CONCLUSION: In this study we evaluated the heart rate recovery or deceleration in diabetic patients with albuminuria and without microalbuminuria in recovery phase after exercise test. We found out that heart rate recovery at the second minute in the case and control groups has statistically significant difference but at the first minute, it did not. Keywords: Diabetes Mellitus, Exercise Test, Heart Rate Recovery
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
13
Association between markers of systemic inflammation, oxidative stress, lipid profiles, and insulin resistance in pregnant women
172
178
10349
EN
Zatollah
Asemi
Assistant Professor, Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran
Shima
Jazayeri
Assistant Professor, Department of Nutrition and Biochemistry, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Mohammad
Najafi
Assistant Professor, Department of Biochemistry, School of Medicine, Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran
Mansooreh
Samimi
Assistant Professor, Department of Gynecology and Obstetrics, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran
Farzad
Shidfar
Associate Professor, Department of Nutrition and Biochemistry, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Zohreh
Tabassi
Assistant Professor, Department of Gynecology and Obstetrics, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran
MohamadEsmaeil
Shahaboddin
Assistant Professor, Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran
Ahmad
Esmaillzadeh
Associate Professor, Food Security Research Center AND Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2012
07
24
BACKGROUND: Increased levels of pro-inflammatory factors, markers of oxidative stress and lipid profiles are known to be associated with several complications. The aim of this study was to determine the association of markers of systemic inflammation, oxidative stress and lipid profiles with insulin resistance in pregnant women in Kashan, Iran. METHODS: In a cross-sectional study, serum high sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-α), fasting plasma glucose (FPG), serum insulin, 8-oxo-7, 8-dihydroguanine (8-oxo-G), total cholesterol, triglyceride, HDL-cholesterol, and plasma total antioxidant capacity (TAC) were measured among 89 primigravida singleton pregnant women aged 18-30 years at 24-28 weeks of gestation. Pearson’s correlation and multiple linear regressions were used to assess their relationships with homeostatic model assessment of insulin resistance (HOMA-IR). RESULTS: We found that among biochemical indicators of pregnant women, serum hs-CRP and total cholesterol levels were positively correlated with HOMA-IR (β = 0.05, P = 0.006 for hs-CRP and β = 0.006, P = 0.006 for total cholesterol). These associations remained significant even after mutual effect of other biochemical indicators were controlled (β = 0.04, P = 0.01 for hs-CRP and β = 0.007, P = 0.02 for total cholesterol). Further adjustment for body mass index made the association of hs-CRP and HOMA-IR disappeared; however, the relationship for total cholesterol remained statistically significant. CONCLUSION: Our findings showed that serum total cholesterol is independently correlated with HOMA-IR score. Further studies are needed to confirm our findings. Keywords: Inflammation, Oxidative Stress, Insulin Resistance, Pregnancy
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
13
Effects of a comprehensive cardiac rehabilitation program on quality of life in patients with coronary artery disease
179
185
10350
EN
Marzieh
Saeidi
MSc Student, Department of Physiotherapy, School of Rehabilitation, Isfahan University of Medical Sciences AND Physiotherapist of Shariati Hospital, Treatment Management of Isfahan Social Security Organization, Isfahan, Iran
Samaneh
Mostafavi
Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Hosein
Heidari
Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Sepehr
Masoudi
Student, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2012
09
11
BACKGROUND: Health-related quality of life is an important factor to evaluate effects of different interventions in cardiovascular diseases. Improvement in quality of life (QOL) is an important goal for individuals participating in cardiac rehabilitation (CR) programs. The purpose of this study was to assess the impact of comprehensive CR on QOL in patients with cardiovascular disease (CAD). METHODS: In this quasi-experimental before-after study, the files of 100 patients with CAD who were referred to rehabilitation department of Isfahan Cardiovascular Research Institute were studied using a consecutive sampling method. Data collection was performed from the patient's files including their demographics, ejection fraction, functional capacity, and resting heart rate. All patients participated in a comprehensive CR program and completed the validated questionnaire Short-Form 36 Health Status Survey (SF-36), before and after CR program. Data was analyzed based on sex and age groups (≥ 65 and < 65 years) using independent t-test and paired t-test (to compare variables between groups and before and after CR, respectively). RESULTS: After CR, scores of all physical domains of the SF-36 including physical function (PF), physical limitation (PL), body pain (BP) and vitality (V) in addition to general health (GH) were significantly improved in all patients (P < 0.05) compared to the baseline. Patients with age < 65 years had greater improvements in mental health (MH) and social function (SF) than patients with age ≥ 65 years (P < 0.05). Women had greater improvement in PF, V and MH compared to men (P < 0.05). CONCLUSION: These results indicated that CR can improve QOL in cardiac patients especially in women. Elderly patients get benefit the same as other patients in physical domains. Keywords: Quality of Life, Cardiac Rehabilitation, Cardiovascular Diseases
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
13
Effect of continuous care model on lifestyle of patients with myocardial infarction
186
191
10351
EN
Zahra
Molazem
Assistant Professor, Department of Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
Soheila
Rezaei
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
Zinat
Mohebbi
Department of Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran
Mohammad-Ali
Ostovan
Associate Professor, Department of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Sareh
Keshavarzi
Assistant Professor, Department of Epidemiology, School of Health and Nutrition, Shiraz University of Medical Sciences, Shiraz, Iran
Journal Article
2012
10
31
BACKGROUND: Myocardial infarction (MI) is a life threatening disease that influences the physical, psychological and social dimensions of the individual. Improper lifestyle is one of the causes of this disease. The use of nursing models could be one of the important and fundamental steps in changing the risk factors associated with MI. This study was carried out to evaluate the effect of continuous care model on the lifestyle of patients with MI. METHODS: This randomized clinical trial was carried out on 70 patients with MI in coronary care units of hospitals affiliated to Shiraz University of Medical Sciences. Enrolled patients were randomly assigned to intervention or control groups using a randomization list (random permutated blocks with length 4). The continuous care model was used for 35 patients in the intervention group for a period of 3 months and in the control group, the usual cares were applied for 35 patients. Data were collected through lifestyle questionnaire before the intervention and 3 months after. The data were analyzed using chi-square, independent t-test and paired t-test. RESULTS: Patients in the intervention group showed significant improvements in lifestyle (125.6 ± 15.4 vs. 180.1 ± 19.9). Moreover, the lifestyle score of intervention group was significantly better than that of the control group (117.9 ± 22.0 vs. 180.1 ± 19.9; P < 0.001) after three months. CONCLUSION: Applying a continuous care model had positive effects on the lifestyle of patients with Myocardial Infarction. In order to reduce the risk factors and improve the lifestyle of patients with MI, nurses could use this model to create an effective change. Keywords: Myocardial Infarction, Lifestyle, Continuous Care Model
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
13
Preconditioning by isoflurane as a volatile anesthetic in elective coronary artery bypass surgery
192
197
10352
EN
Amjad
Kiani
Cardiac Anesthesiologist, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Mohsen
Mirmohammad Sadeghi
Associate Professor, Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Mojgan
Gharipour
PhD Candidate, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0002-0375-4874
Niloofar
Farahmand
Islamic Azad University, Najafabad Branch, Isfahan AND 5 Delasa Heart Center, Sina Hospital, Isfahan, Iran
Laleh
Hoveida
PhD Candidate, Department of Microbiology, Islamic Azad University, Felavarjan Branch, Isfahan, Iran
Journal Article
2012
12
26
BACKGROUND: Some pharmacological preconditioning approaches are utilized as an effective adjunct to myocardial protection, particularly following cardiac procedures. The current study addressed the potential clinical implications and protective effects of isoflurane as an anesthetic most applicable on postoperative myocardial function measured by cardiac biomarkers. METHODS: 46 patients were included in the study. In 23 of them, preconditioning was elicited after the onset of cardiopulmonary bypass via a 5-minute exposure to isoflurane (2.5 minimum alveolar concentration), followed by a 10-minute washout before aortic cross clamping and cardioplegic arrest. 23 case-matched control patients underwent an equivalent period (15 minutes) of pre-arrest isoflurane-free bypass. Outcome measurements included creatine phosphokinase (CPK) and creatine kinase–MB (CK-MB) levels until 24 hours after the surgery. RESULTS: None of the differences in enzyme levels at baseline and 24 hours after surgery between the two groups reached the threshold of statistical significance. The level of CPK was significantly reduced 24 hours after surgery compared with the baseline in the two groups. However, the postoperative release of CPK was consistently smaller in the isoflurane-preconditioned group than in the control group. The release of CK-MB displayed a statistically similar pattern. Multivariate linear regression analysis showed the effect of isoflurane regimen on reducing CPK level within the 24 hours after surgery compared with placebo. CONCLUSION: Our study supports the cardio protective effect of isoflurane and the role of pharmacological preconditioning of the human heart by this volatile anesthetic during elective coronary artery bypass surgery. Keywords: Preconditioning, Isoflurane, Volatile Anesthetic, Coronary Artery Bypass Surgery
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
14
Lipid profile in antipsychotic drug users: A comparative study
198
202
10353
EN
Hamidreza
Roohafza
Assistant Professor, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0003-3582-0431
Azam
Khani
Research Assistant, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
0000-0003-4423-7694
Hamid
Afshar
Associate Professor, Psychosomatic Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Mohammad
Garakyaraghi
Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Afshin
Amirpour
Assistant Professor, Department of Mental Health, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Basir
Ghodsi
Research Assistant, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
02
16
BACKGROUND: Schizophrenic patients who receive antipsychotic drugs may be highly prone to metabolic disorders such as weight gain, dyslipidemia, and insulin resistance. The objective of the present study was to compare the effect of atypical and conventional antipsychotics on lipid profile. METHODS: 128 schizophrenic patients were enrolled into the study. Patients were divided into two groups. One group had received one type of atypical antipsychotic drug, and, the other, one type of conventional antipsychotic drug. They were considered as atypical and conventional groups. Moreover, both groups had not used any other antipsychotic drugs during the past year. Demographic data and food frequency questionnaire were completed by the participants. Serum triglyceride, total cholesterol (TC), high-density lipoprotein and low-density lipoprotein (LDL) cholesterols, and apolipoprotein A and B (Apo B) were tested by blood sample drawing after 12 hours of fasting through the antecubital vein. Student’s t-test was used to compare atypical and conventional groups. RESULTS: There was no significant difference in age, gender, duration of illness, period of drug consumption, and age at onset of illness in the two groups. Patients in the atypical group used clozapine and risperidone (46.9%) more than olanzapine. In the conventional group 81.3% of patients used phenothiazines. Comparison between lipid profile in the conventional and atypical groups showed a significantly higher mean in TC (P = 0.01), LDL (P = 0.03), and Apo B (P = 0.01) in conventional group than the atypical group. CONCLUSION: In schizophrenic patients, the level of lipid profile had been increased in both atypical and conventional antipsychotic users, especially conventional users, so the effect of antipsychotic drugs should be investigated periodically. Keywords: Atypical Antipsychotic, Conventional Antipsychotic, Lipid Profile
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
01
Clinical associations between renal dysfunction and vascular events: A literature review
203
209
10354
EN
Reza
Karbasi-Afshar
Assistant Professor, Department of Cardiology AND Cardiovascular Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
Amin
Saburi
Researcher, Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
Saeed
Taheri
Researcher, Dr. Taheri Medical Research Group, Baqiyatallah University of Medical Sciences, Tehran, Iran
Journal Article
2013
01
10
Chronic kidney disease affects several other organs of the human body, and causes high levels of morbidity and mortality due to these effects. The cardiovascular system is probably the most vulnerable organ to a decrease in kidney function, and responds very fast to this effect. To the extent that, more kidney disease patients die of cardiovascular events than that of the original renal disease. Moreover, cerebrovascular events have been confirmed to increase, and to have inferior outcomes on the general population. In this review article, we aim to review studies investigating effects of renal disease on vascular events. Keywords: Renal Disease, Cardiovascular Disorders, Dialysis, Myocardial Infarction, Risk Factor
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
13
Traumatic right pericardial laceration with tension pneumopericardium associated with hemodynamic instability: A case report
210
212
10355
EN
Seyhan
Yılmaz
Yozgat Province Hospital, Heart-Vessel Surgery, Yozgat, Turkey
Ayşegül
KOÇ
Yıldırım Beyazıt University, Ankara, Turkey
Journal Article
2012
12
23
BACKGROUND: Pneumopericardium is a rare complication following thoracic trauma, and urgent treatment is rendered necessary when it causes tension pneumopericardium due to cardiac tamponade. CASE REPORT: The case presented here is a right pericardial laceration with tension pneumopericardium due to falling from a height, presenting to the emergency clinic of our hospital with hemodynamic instability. CONCLUSION: Pneumopericardium that might develop due to blunt thoracic trauma can easily be diagnosed, may result in cardiac tamponade, and is a potentially fatal pathology without treatment. Keywords: Pneumopericardium, Trauma, Cardiac Tamponade, Fall
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
14
Five chambered heart or large atrial appendage aneurysm: A report of two cases
213
215
10356
EN
Mohsen
Mirmohammadsadeghi
Department of Cardiovascular Surgery, Isfahan University of Medical Sciences, Isfahan, Iran
Yalda
Kiani
Department of Cardiology, Isfahan University of Medical Sciences, Isfahan, Iran
Ali
Nasr
Department of Cardiology, Isfahan University of Medical Sciences, Isfahan, Iran
Reihaneh
Zavvar
Department of Cardiology, Isfahan University of Medical Sciences, Isfahan, Iran
Mohaddeseh
Behjati
Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences,
Isfahan, Iran
Majid
Rabbani
Isfahan University of Medical Sciences, Isfahan, Iran
Elham
Majidi
Department of Cardiology, Isfahan University of Medical Sciences, Isfahan, Iran
Poya
Mirmohammadsadeghi
Isfahan University of Medical Sciences, Isfahan, Iran
Journal Article
2013
02
17
BACKGROUND: Isolated intrapericardial LAA aneurysm is a rare cardiac anomaly which manifests with angina, dyspnea on exertion (DOE), systemic embolization, arrhythmia, and congestive heart failure. CASE REPORT: A 30-year-old female and a 46-year-old male were referred for evaluation of abnormal cardiac contour on chest radiograph and echocardiographic findings and non-specific symptoms. Transesophageal echocardiography suggested left atrial appendage (LAA) mass filled with clots. The mass had no compression on cardiac chambers and global ejection fraction was within normal limits. The intraoperative diagnosis was isolated congenital LAA aneurysm. After confirmation of the diagnosis, it was resected. She was discharged with uneventful postoperative course. At follow-up she was asymptomatic. CONCLUSION: These cases demonstrate the role of on-time surgical approaches in the prevention of fatal complication of this rare cardiac anomaly. Keywords: Left Atrial Appendage, Aneurysm, Clot
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
9
3
2013
05
01
Journal Index
10347
EN
Index
Journal
0000-0002-1825-0097
Journal Article
2013
06
23
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