Cardiovascular research institute, Isfahan University of Medical SciencesARYA Atherosclerosis Journal1735-395516520200912Factors influencing academic autonomy and its dimensions in Isfahan Cardiovascular Medical and Research Center, Iran: A mixed-method study2132191074510.22122/arya.v16i5.2070ENMohammad Reza ShafeieDepartment of Public Management, School of Management, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran0000-0003-3913-4703Saeid SharifiAssistant Professor, School of Management, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran0000-0001-5643-8157Journal Article20191001BACKGROUND: The issue of academic autonomy along with the reduced authority of the government for handling the service-providing section is considered an urgent demand for most of the organizations including hospitals.METHODS: The method of research was a combination of quantitative and qualitative methods from sequential exploratory studies type. In qualitative part, descriptive-phenomenological method using seven-step Colaizzi method and in quantitative part, survey method was used. Statistical population of research of the first part included key experts of the academic autonomy field who were selected purposefully and based on the criterion. With 8 persons, data were saturated. Data collection tool of this part was semi-structured and deep interview. Validation of data was performed by outsider auditors as well as through returning to the interviewees. In quantitative part, a 60-question questionnaire made by the authors was used for data collection which was distributed among officials including hospital managers and key stakeholders of the academic autonomy process in a heart hospital who were 98 persons. Superficial and content validity of the questionnaire was estimated as much as 0.70 for all items. Modeling analysis in inferential level was done through Akaike scale regression.RESULTS: Academic autonomy is in three dimensions: economic, scientific, and organizational and inter-organizational, intra-organizational, and extra-organizational factors contribute to it from which scientific autonomy is more important compared to other factors. Moreover, intra-organizational factors have more contribution to the academic autonomy of these centers.CONCLUSION: The results of this study will be a good guide for academic autonomy of medical centers. In order to achieve academic autonomy, it is more important to pay attention to factors such as autonomy culture capacity, independent signing treaties and international documents, and science-centered society.https://arya.mui.ac.ir/article_10745_3eba19b25f19433457702a96a8fe8887.pdfCardiovascular research institute, Isfahan University of Medical SciencesARYA Atherosclerosis Journal1735-395516520200912Adherence to the algorithmic approach for diagnosis of pulmonary embolism: A teaching hospital experience, Shiraz, Iran2202251074610.22122/arya.v16i5.2040ENVahid MohammadkarimiAssistant Professor, Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran0000-0002-7356-1795Samaneh AhsantResident, Student Research Committee AND Department of Internal Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranMohammad Hadi BagheriProfessor, Medical Imaging Research Center AND Department of Radiology, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, IranReza JalliAssociate Professor, Medical Imaging Research Center AND Department of Radiology, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, IranAli HosseinipourAssistant Professor, Non-Communicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, IranSeyed Masoom MasoompourProfessor, Non-Communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran0000-0002-0129-7155Journal Article20190709BACKGROUND: We evaluated to see if the algorithmic approach of pulmonary embolism (PE) [Wells’ score, followed by D-dimer test and computed tomography pulmonary angiography (CTPA)] is appropriately followed in teaching hospitals of Shiraz, Iran.METHODS: From October 2012 to October 2013, we prospectively calculated Wells’ score for all patients who underwent CTPA with clinical suspicion to PE; patients with low probability who had not checked the D-dimer or had low level of D-dimer were considered as non-adherent to the guideline and those with high level of D-dimer or high probability of Wells’ score were labeled as adherent to the PE guideline. CTPA scans were independently reported by two radiologists.RESULTS: During study period, 364 patients underwent CTPA to rule out PE, of which 125 (34.3%) had Wells’ score > 4 (high probable risk) and 239 had Wells’ score ≤ 4. Amongst low probable risk patients (Wells’ score ≤ 4), only 32 patients had undergone the D-dimer test (23 patients had high level of D-dimer). Based on the algorithmic approach, patients with suspected PE, patients with high probability (125 patients), and patients with low probability with elevated D-dimer level (23 patients) were considered as adherent to the PE guideline; consequently, the total adherence to PE guideline was 148 out of 364 (40.6%).CONCLUSION: We followed the algorithmic approach guideline in about 40.0% of cases; however, we should pay more attention to the algorithmic approach in patients with suspected PE.https://arya.mui.ac.ir/article_10746_9e0f3c612c9843a469d3070ffdb10867.pdfCardiovascular research institute, Isfahan University of Medical SciencesARYA Atherosclerosis Journal1735-395516520200912The effects of aerobic training, resistance training, combined training, and healthy eating recommendations on lipid profile and body mass index in overweight and obese children and adolescents: A randomized clinical trial2262341074710.22122/arya.v16i5.1990ENAlireza AhmadiAssociate Professor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-2462-0162Fahimeh Moheb-MohammadiDepartment of Pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-5350-0645Zohreh Sadat NavabiPediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranMehdi DehghaniDepartment of Exercise Physiology, School of Sport Sciences, University of Isfahan, Isfahan, IranHossein HeydariCardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranFiroozeh SajjadiInterventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran0000-0001-6716-7874Somaieh KhodarahmiIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranJournal Article20190402BACKGROUND: The aim of this study was to evaluate the effects of 8 weeks of aerobic training, resistance training (RT), combined training, and nutritional recommendations on lipid profile and body mass index (BMI) in obese and overweight children and adolescents.METHODS: This randomized, clinical trial was conducted on 120 children and adolescents (10-19 years of age) with overweight and obesity. Participants were divided into 4 groups, the 3 intervention groups of high-intensity interval training (HIIT), RT, and combined training, and 1 non-exercising control group with healthy eating recommendations. We considered 24 sessions of training during 8 weeks for the intervention groups. The participants’ anthropometric indices and lipid profile were assessed before and after the intervention.RESULTS: There were no significant differences between the groups in terms of anthropometric indices and lipid profiles before the intervention. After the intervention, there was a significant difference between the groups in terms of HDL level; the control group (37.70 ± 9.45) and the HIIT group (43.65 ± 9.09) displayed the lowest and highest mean, respectively (P = 0.040). Comparison of physical variables and blood lipid profiles before and after the intervention showed a significant difference in waist circumference (P = 0.030), hip circumference (P ≤ 0.001), and HDL level (P = 0.040) in RT, HIIT, combined, and control groups.CONCLUSION: These results demonstrate that the combined training program and HIIT program with nutritional recommendations in overweight and obese children and adolescents were more effective in reducing BMI and hip circumference, respectively.https://arya.mui.ac.ir/article_10747_713675d7b36103f4cdd34ffba0d01b42.pdfCardiovascular research institute, Isfahan University of Medical SciencesARYA Atherosclerosis Journal1735-395516520200912The effect of calcium in water hardness on digoxin plasma levels in an experimental rat model2352431074810.22122/arya.v16i5.2112ENShabnam ShahsavandAssistant Professor, Department of Physiology and Pharmacology, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran0000-0003-0117-6502Mohammad MoshirfarDepartment of Orthopedic Surgery, Tehran University of Medical Sciences, Tehran, IranSeyed Hassan Seyed-SharifiDepartment of General Surgery, Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, IranMohammad Amin Younessi-HeraviDepartment of Medical Physics and Radiology, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, IranReza GhasemiAssistant Professor, Department of Cardiology, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, IranMorteza ValaeiDepartment of Internal Medicine, Razavi Hospital, Imam Reza International University, Mashhad, IranMohsen YaghubiDepartment of Extra-Corporeal Circulation, Razavi Hospital, Imam Reza International University, Mashhad, Iran0000-0001-8061-3779Journal Article20200130BACKGROUND: Digoxin is a drug for ventricular rate control in atrial fibrillation (AF). The major challenge in digoxin therapy is to adjust the appropriate concentration range for this drug due to its narrow therapeutic index. Unique physiochemical properties of drinking water affect the pharmacological actions and delivery of drugs to the body whether they are administered orally, topically, or by injection. The aim of this study was to evaluate water hardness effect on digoxin therapy in an experimental rat model.METHODS: 48 rats weighing 200-220 g were randomly assigned to three groups that received drinking water with 50, 400, and 800 mg/l hardness degrees for 28 days. Then each group was assigned into two groups. One received digoxin 0.2 mg/kg a day orally for four days. The other group received normal saline (as control group). Continuous recording of electrocardiogram (ECG) was performed by PowerLab system (AD Instruments Company) before and day 4 of digoxin treatment. Then serum samples were collected and assessed for digoxin, sodium, potassium, calcium, magnesium, blood urea nitrogen (BUN), and creatinine levels.RESULTS: Water hardness in the range of 50-800 mg/l had no effect on serum digoxin levels (P > 0.050), but consuming hard drinking water (400 and 800 mg/l) could increase serum calcium levels and then cause mortality (37.5% in both groups), following changes in ECG due to digoxin consumption.CONCLUSION: Consuming hard drinking water probably interferes with digoxin pharmacodynamics in the way of toxicity induction.https://arya.mui.ac.ir/article_10748_6d6e4800343550c8a88d05a8281b6182.pdfCardiovascular research institute, Isfahan University of Medical SciencesARYA Atherosclerosis Journal1735-395516520201007The commencement of congenital heart diseases registry in Isfahan, Iran: Methodology and design2442471074910.22122/arya.v16i5.1913ENBahar DehghanAssistant Professor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-4205-829XMohammad Reza SabriProfessor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran0000-0001-9726-6144Mohsen HosseinzadehAssistant Professor, Department of Pediatric Cardiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IranAlireza AhmadiAssociate Professor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran0000-0002-2462-0162Mehdi GhaderianAssociate Professor, Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran0000-0001-6140-7750Nizal SarrafzadeganProfessor, Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences,
Isfahan, IranHamidreza RoohafzaAssistant Professor, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran0000-0003-3582-0431Journal Article20181114BACKGROUND: Reported prevalence of congenital heart diseases (CHDs) varies widely among studies worldwide. The incidence of CHD, total number of pediatric and adult grown-up congenital heart disease (GUCH), is not determined in Iran. Therefore, we have designed a system to register the information of patients with CHD for the first time in our country.METHODS: CHD registry is a database in which the patients' data are collected by five pediatric cardiologists from three referral hospitals affiliated to Isfahan University of Medical Sciences, Isfahan, Iran, and five outpatient clinics. We enrolled patients with CHD either as new cases who were referred for evaluation of potential CHD or those who were being followed within the outpatient clinics and entered their whole information in a website specifically designed for it. All the information was collected from checklist by those pediatric cardiologistsRESULTS: From April 2017 to April 2020, after developing the forms and website, the Quality Control Committee evaluated the first 558 files. 73 files (13%) needed major revisions. Among them, 34 (46%) files were omitted totally and the 39 remaining files were revised and completed. After that revision, we changed our checklist and gathered about 1600 patients accordingly.CONCLUSION: Registry of CHDs not only improves epidemiologic studies but also assists researchers to understand how much a disease management is useful and how to raise the quality of cares and outcomes. Moreover, this provides a better insight for policymakers to understand the extent of health-related problems as well as the issues related to the prevention and management of CHDs all around the world. https://arya.mui.ac.ir/article_10749_ac1bc645e02305cb46a85144d93e188a.pdfCardiovascular research institute, Isfahan University of Medical SciencesARYA Atherosclerosis Journal1735-395516520200912The Recommended Food Score and Healthy Nordic Food Index in cardiovascular disease and stroke: A systematic review2482571075010.22122/arya.v16i5.2067ENMelika HajjarStudent Research Committee AND Department of Nutrition Community, School of Nutrition, Shahid Beheshti University of Medical Sciences, Tehran, Iran0000-0002-6340-6847Arezoo RezazadehDepartment of Community Nutrition, National Nutrition and Food Technology Research Institute, School of Nutrition Sciences and Food Technology, Shahid Behehshti University of Medical Sciences, Tehran, Iran0000-0003-2218-8705Journal Article20190914BACKGROUND: Cardiovascular disease (CVD) includes a group of heart and coronary disorders that can be prevented by promoting the quality of an individual’s diet. The Recommended Food Score (RFS) and Healthy Nordic Food Index (HNFI) are suggested for the assessment of diet quality and as indicators of dietary exposures related to disease. The aim of this study was to systematically review the association of the RFS and the HNFI with CVD and stroke.METHODS: Articles were identified by searching PubMed, Google Scholar, and ScienceDirect using relevant keywords for articles published until December 2018. The inclusion criteria were all types of observational studies and English language. Non-English and irrelevant studies were excluded.RESULTS: In total, 14 studies met the inclusion criteria. Of the 7 studies that investigated the association between the RFS and CVD, 6 articles showed a lower risk of CVD in individuals who obtained a higher RFS and lower non-RFS (n-RFS) score. Studies that investigated the relation between RFS and stroke (n = 2) showed that achieving a higher RFS could decrease the risk of stroke. Of the 4 studies that assessed the relationship between HNFI and CVD, 3 showed that adherence to HNFI were related with lower risk of CVD/stroke. However, one study did not show any relationship.CONCLUSION: A higher RFS may result in a decrease in the risk of CVD and stroke. Due to the inconsistency of the findings related to HNFI, more studies are needed to approve the negative relationship between HNFI and CVD.https://arya.mui.ac.ir/article_10750_85cf8651db2913e3cf713ff2d0622521.pdfCardiovascular research institute, Isfahan University of Medical SciencesARYA Atherosclerosis Journal1735-395516520200929What thought to be a cardiac tumor turns out to be a remnant of former surgery2582601075110.22122/arya.v16i5.1965ENAnahita TavoosiAssistant Professor, Department of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran0000-0003-0491-0231Mehrdad SalehiProfessor, Department of Cardiac Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranAkram SardariAssistant Professor, Department of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranSamira ShiraziResident, Department of Cardiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranFaeze SalahshourAssistant Professor, Department of Radiology, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, IranPejman MansouriResident, Tehran Heart Center, Tehran University of Medical Sciences, Tehran Iran0000-0001-6407-0241Journal Article20190202BACKGROUND: A textiloma is a rare retained surgical swab with probable serious post-operation complications.CASE REPORT: Here, we reported an asymptomatic patient who had past history of coronary artery bypass grafting (CABG) fourteen months ago and referred to our institute for left atrial mass removal. Echocardiography and chest computed tomography (CT) scan revealed a non-homogenous non-mobile mass and a heterogeneous lesion with low-density as well as high-density areas with spot calcification and gas bubbles at left atrium level, respectively.CONCLUSION: Despite being rare after CABG, textiloma should be considered in the differential diagnosis in case of any suspicious chest mass even in asymptomatic patients.https://arya.mui.ac.ir/article_10751_8ffbcf694ef08698c7bd154eea840eb4.pdfCardiovascular research institute, Isfahan University of Medical SciencesARYA Atherosclerosis Journal1735-395516520200912Left ventricular clot: Newly known increased complication of air pollution in dilated cardiomyopathy (DCM)2612621075210.22122/arya.v16i5.2116ENAzin AlizadehaslProfessor, Rajaie Cardiovascular Medical and Research Center AND Department of Cardio-Oncology, Iran University of Medical Sciences, Tehran, Iran0000-0002-8550-1378Asghar MohamadiCardiovascular Research Center, Shahid Rahimi Hospital, Lorestan Universiry of Medical Sciences, Khorramabad, IranJournal Article20200204This article does not have an abstract https://arya.mui.ac.ir/article_10752_f171a3d9abade267c61c590764e37ed7.pdfCardiovascular research institute, Isfahan University of Medical SciencesARYA Atherosclerosis Journal1735-395516520200901Journal Index1074410.22122/arya.v16i5.2400ENIndex JournalArya0000-0002-1825-0097Journal Article20210330Click to download the index of this issue https://arya.mui.ac.ir/article_10744_a4f863cfed732b2de298b78484367ed5.pdf