Cardiovascular research institute, Isfahan University of Medical Sciences ARYA Atherosclerosis Journal 1735-3955 20 Issue 1 2024 02 01 Intramyocardial dissecting hematoma: A systematic review and pooled analysis of available literature 62 71 31089 10.48305/arya.2023.42244.2927 EN Reihane Zavar Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0001-8304-4815 Azam Soleimani Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran‎ 0000-0003-2529-5223 Marzieh Tajmirriahi Hypertension research center, cardiovascular research institute, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0003-4852-7103 Afshin Amirpour Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0002-8869-9455 Shaghayegh Mahmoudiandehcordi School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Faezeh Farhang Department of Cardiology, School of Medicine, Chamran Hospital, Isfahan University of Medical Sciences, Isfahan, Iran 0009-0005-7043-1943 Journal Article 2023 11 02 BACKGROUND: The current systematic review and pooled analysis were conducted to answer several questions using findings from case reports and case series as follows: (1) Demographic characteristics; (2) clinical findings; (3) management approach; and (4) prognosis of individuals diagnosed with intramyocardial dissecting hematoma.<br />METHODS: Electronic databases, including PubMed (Medline), Scopus, and Web of Science, were systematically searched from the earliest available date up to February 2023 using selected keywords. All analyses were performed using SPSS software version 27 (IBM Corp, Armonk, NY, USA), and a P-value less than 0.05 was considered statistically significant.<br />RESULTS: A total of 77 patients diagnosed with Intramyocardial dissecting hematoma (IDH) comprised the study population, with a mean (standard deviation) age of 58.72 (13.99) years, of which 22.1% were women. Patients of higher age experienced a higher risk for mortality compared to younger subjects (OR=1.05, 95% CI: 1.01, 1.10; P=0.014). In addition, the implementation of angiography (OR=0.25, 95% CI: 0.08, 0.71; P=0.010) and cardiac magnetic resonance (OR=0.19, 95% CI: 0.06, 0.60; P=0.004) in the context of diagnosis reduced the risk of death compared to those who did not receive these interventions. Similarly, the diagnosis of pericardial effusion significantly increased the risk of mortality compared to those without pericardial effusion (OR=3.92, 95% CI: 1.27, 12.07; P=0.017).<br />CONCLUSION: The authors found that older patients experience a poor prognosis compared to younger ones. In addition, the utilization of angiography and cardiac magnetic resonance improves the prognosis of individuals. Likewise, the diagnosis of pericardial effusion in patients with IDH increases the odds of mortality. https://arya.mui.ac.ir/article_31089_c73edcecd97f8e999b5cd937d5e6827e.pdf