Cardiovascular research institute, Isfahan University of Medical Sciences ARYA Atherosclerosis Journal 1735-3955 19 1 2023 01 01 Management of Patients with Vascular Ehlers-Danlos Syndrome and Acute Coronary Syndrome: a Case Report 61 64 30973 10.48305/arya.2022.11722.2343 EN Ilenia Di Liberto Department of Interventional Cardiology, San Giovanni Di Dio Hospital, Agrigento, Italy 0000-0002-1456-8962 Gerlando Pilato Department of Interventional Cardiology, San Giovanni Di Dio Hospital, Agrigento, Italy Giuseppe Caramanno Department of Interventional Cardiology, San Giovanni Di Dio Hospital, Agrigento, Italy Journal Article 2020 12 23 Background: Ehlers-Danlos syndrome (EDS) is a hereditary collagen vascular disorder characterized by joint hypermobility, skin hyperextensibility, and tissue fragility. Vascular EDS (vEDS) is a subtype of EDS which is characterized by vascular fragility.<br />Case presentation: This is a case report of a young man with vEDS hospitalized for myocardial infarction. He was presented with a coronary dissection and developed aortic dissection, coronary rupture, and cardiac tamponade until death. <br />Conclusion: This case report highlights how patients with vEDS and acute coronary syndrome show a higher risk of vascular complications compared with other patients, and their admission to the institution with a cardiac surgery room could be helpful and safe for better management of the complications. Non-invasive methods could be useful to exclude other vascular diseases, before the emergency coronary intervention. https://arya.mui.ac.ir/article_30973_c9c824652337e9217278c040b326e9a9.pdf