Cardiovascular research institute, Isfahan University of Medical Sciences ARYA Atherosclerosis Journal 1735-3955 14 1 2018 01 27 A rare case of spontaneous and simultaneous multivessel coronary artery spasm leading to multisite myocardial infarction and ventricular fibrillation 41 43 10618 10.22122/arya.v14i1.1683 EN Leili Iranirad Assistant Professor, Department of Cardiology, School of Medicine, Qom University of Medical Sciences, Qom, Iran Mohammad Saleh Sadeghi Researcher AND General Practitioner, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran Journal Article 2017 09 26 BACKGROUND: Coronary artery spasm (CAS) can result in life-threatening arrhythmia and sudden cardiac death. Although this disorder has been known for a long time, little is known about it, and its mechanisms have been not identified yet.CASE REPORT: We describe a 52-year-old woman with no significant cardiovascular risk factors who experienced several episodes of spontaneous and coincident multivessel coronary artery spasm, which led to myocardial infarction as well as malignant arrhythmias. Coronary angiography revealed severe migratory narrowing in the left anterior descending artery and right coronary artery.CONCLUSION: Simultaneous multivessel coronary artery spasm develop multisite myocardial infarction (MI), and malignant arrhythmias could occur even in the absence of significant stenosis and triggering factors, which would lead to an increased risk of life-threatening cardiac events. https://arya.mui.ac.ir/article_10618_39b1b0fc4a4f43d604bbb161072120b9.pdf