Cardiovascular research institute, Isfahan University of Medical Sciences ARYA Atherosclerosis Journal 1735-3955 7 4 2012 03 08 The effects of a comprehensive community trial on cardiometabolic risk factors in adolescents: Isfahan healthy heart program 184 190 10254 EN Roya Kelishadi Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran Noushin Mohammadifard PhD Candidate, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0003-1776-1060 Nizal Sarrafzadegan Professor, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0002-8352-0540 Fatemeh Nouri MSc Student, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran Rezvan Pashmi BSc, Isfahan Provincial Health Center, Isfahan University of Medical Sciences, Isfahan, Iran Ahmad Bahonar General Practitioner, MPH, Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran Hossein Heidari General Practitioner, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0002-4231-9525 Sedigheh Asgary Professor, Physiology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0001-7724-4802 Maryam Boshtam PhD Candidate, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran 0000-0003-0946-3354 Alireza Mardani BSc, Isfahan Provincial Health Center, Isfahan University of Medical Sciences, Isfahan, Iran, And BSc, Najaf Abad Health Center, Isfahan University of Medical Sciences, Isfahan, Iran. Journal Article 2012 01 22 BACKGROUND: This study aimed to assess the effects of a 6-year-long communityparticipatoryprogram including school-based interventions on mean values and prevalence ofcardiometabolic risk factors among adolescents.METHODS: The interventions of this community trial, conducted from 2000 to 2007 in Iran,targeted the whole population (of nearly two millions) living in two cities considered as theintervention area (IA) in comparison with a reference area (RA). Data from surveys conductedbefore and after interventions was used to compare the differences between the secondaryschool students of the IA and RA.RESULTS: The prevalence of hypercholesterolemia and hypertriglyceridemia declinedsignificantly in girls and boys in the IA (P < 0.01). The prevalence of high LDL-C decreasedsignificantly in the girls in the RA (P = 0.002). Among both sexes in the IA, the prevalence oflow HDL-C increased significantly (P < 0.001), whereas it decreased in the girls and boys in theRA (P = 0.04). Although in the IA, the prevalence of overweight and obesity decreasedsignificantly in girls (P = 0.001), it increased in boys (P = 0.001) as well as in the girls of the RA(P = 0.01).CONCLUSION: By performing school-based interventions, our study was successful, at least inpart, in controlling some cardiometabolic risk factors in adolescents. Such modifications mayhave long-term impacts on non-communicable diseases prevention in adulthood.Keywords: Prevention, Adolescents, Lifestyle, Community Trial, Iran. https://arya.mui.ac.ir/article_10254_805b74daca86ea2e20ca9c166ee52f9e.pdf