Cardiovascular research institute, Isfahan University of Medical Sciences ARYA Atherosclerosis Journal 1735-3955 3 4 2010 12 08 DETERMINANTS OF SUBOPTIMAL BLOOD PRESSURE CONTROL IN HYPERTENSIVE PATIENTS: 24-HOUR AMBULATORY BLOOD PRES-SURE MONITORING 10092 EN Mansoor Moazenzadeh MD. Assistant Professor of Cardiology, Kerman Physiology Research Center (KPRC), Kerman University of Medical Sciences, Kerman. Ali Mirzazadeh MD. MPh. Kerman Physiology Research Center (KPRC), Kerman University of Medical Sciences, Kerman, Iran. Pooria Salari MD. Research Assistant, Kerman Physiology Research Center (KPRC), Kerman University of Medical Sciences, Kerman, Iran. Journal Article 2010 12 07 Abstract    INTRODUCTION: The study was conducted to define the determinants of suboptimal blood pressure (BP) control among hypertensive patients under treatment and explore a predictive model for detecting the patients at risk for increased BP.    METHODS: We enrolled 97 patients (40 males, 57 females) under treatment for hypertension between June 2006 and May 2007 in Shafa hospital, Kerman, Iran. BP was measured at clinic twice within 5-minute intervals. After setting up ambulatory blood pressure monitoring (ABPM), BP was measured at 30-minute intervals during the day and 60-minute intervals during the night. The frequency of increased BP (more than 140/90 mmHg) was included in a regression model as dependent variable and all the others such as age, sex, body mass index (BMI), drugs and baseline clinical measurements as the predictors.    RESULTS: Increased BP was detected in 44% (95% CI: 38.79%-49.65%) of all measurements during 24-hour monitoring. The frequency of increased BP had a significant relationship with BMI (b=0.35, P=0.001). Clinic's pulse pressure was a significant predicting factor for BP increase (P=0.02).    CONCLUSION: BMI and pulse pressure are the best predictors for being hypertensive during lifetime. Ineffective treatment of hypertension is frequent among the hypertensive patients.      Keywords: Blood pressure control, Pulse pressure, Ambulatory blood pressure monitoring (ABPM), BMI. https://arya.mui.ac.ir/article_10092_c0c3a9fb8385d8e03a46adadde9af3bf.pdf