2024-03-28T17:30:39Z
https://arya.mui.ac.ir/?_action=export&rf=summon&issue=19
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
CONTENT OF LONG CHAIN OMEGA-3 FATTY ACID COMPOSITION IN SOME IRANIAN CANNED FISH
Bahar
Nazari
Seddighe
Asgary
Nizal
Sarrafzadegan
Salbali
Saberi
Noushin
Mohammadifard
Abstract BACKGROUND: Ecological studies have found a negative correlation between the risk of developing heart disease and fish consumption because of their long chain omega-3 fatty acids. This study was undertaken to determine the amounts of the common fatty acid content of several commercial canned fish marketing in Iran, with particular attention to long chain omega-3 fatty acids. METHODS: The most consumed available brands of canned fish were randomly selected seven times from products available in supermarkets. Total lipids were extracted by using the Folch method and prepared for fatty acid analysis. Individual fatty acids were quantified by gas chromatography (GC) with 60 meter capillary column and flame ionization detector. RESULTS: The most common saturated fatty acids (SFA) in Iranian canned fish was palmitic acid (C16:0) followed by stearic acid (C18:0). The amount of all trans fatty acids (TFAs) except elaidic acid (C18:1 9t) was 0%. The highest amount of polyunsaturated fatty acids (PUFAs) related to long chain omega-3 fatty acids include eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The most abundant monounsaturated fatty acids (MUFAs) were oleic acid (C18:1 9c). CONCLUSION: This study showed higher contents of EPA and DHA in Iranian commercially available canned fish compared to the canned fish in other countries. Keywords: Iranian canned fish, fatty acids, long chain omega-3 fatty acids, gas chromatography.
2010
12
01
https://arya.mui.ac.ir/article_10058_da5e62a578400b522bdc461e85db69b6.pdf
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
CORRELATION BETWEEN LAG TIME OF LDL TO IN VITRO OXIDATION AND IN VIVO OXIDIZED LDL IN THE PATIENTS WITH CORONARY ARTERY DISEASE
Hashem
Nayeri
Gholam Ali
Naderi
Ebrahim
Javadi
Sedigheh
Asgary
Abbas
Lotfi
Masoumeh
Sadeghi
Abstract BACKGROUND: The oxidative modification of low density lipoprotein (LDL) is believed to play an important role in the development of atherosclerosis. Thus, measurement of plasma oxidized LDL (OX-LDL) is essential for atherosclerotic diseases, for investigating its relevance to atherosclerotic diseases. We aimed to assess the oxidized LDL in patients with coronary artery disease and correlation between serum oxidized low density lipoprotein and in vitro susceptibility of LDL to oxidation. METHODS: Subjects of the study were selected from patients who undergone angiography (42 patients with coronary artery disease and 40 controls without any evidence of CAD). The susceptibility of LDL to in vitro oxidation was assessed with the addition of a Cuso4 solution. The lag time, propagation rate and maximal diene calculated from the oxidation curve. Biochemical factors (FBS, total cholesterol, TG, LDL, and HDL) were measured in these subjects. SPSS version 15.5 was used to analyze the data, P- value under 0.05 was considered to be significant. RESULTS: The results indicated that the serum OX-LDL concentration was significantly elevated in CAD patients and the lag time was significantly shorter than controls (P < 0.05). These results clearly confirm that LDL from persons with CAD is more susceptible to oxidative modification in vitro than LDL from healthy subjects. The other measured biochemical factors were not significantly different between CAD patients and controls (P > 0.05). Correlation between serum OX-LDL and susceptibility of LDL to in vitro oxidation did not show significant association (P > 0.05). CONCLUSION: our findings suggest that a high OX-LDL concentration and a short LDL oxidation lag time might be independent risk factors for CAD. Keywords: OX-LDL; Lag time; Maximal Diene; Propagation Rate; Susceptibility.
2008
12
01
https://arya.mui.ac.ir/article_10059_290618c4b4f5378f86fa620039069844.pdf
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
ST SEGMENT RESOLUTION IN OPIUM ADDICT PATIENTS AFTER THROMBOLYTIC THERAPY FOR ACUTE MYOCARDIAL INFARCTION
Mohammad
Masoomi
Fatemeh
Ghaemi
Aliakbar
Haghdost
Hamidreza
Rashidinejad
Abstract BACKGROUND: The aim of this study was to assess resolution of ST segment elevation after streptokinase therapy in opium-addict patients with acute myocardial infarction (AMI). METHOD AND MATERIALS: The studied population consisted of AMI patients who have criteria for thrombolytic therapy. Three groups of ST segment resolution were defined: complete resolution (≥ 70%), partial resolution (70% to 30%) and no resolution (< 30%). RESULTS: A total number of 240 patients were studied (126 opium addicts and 114 non-addicts). Overall, 52.5% of addicts and 38.7% of non-addicts had complete ST segment resolution (P = 0.06). The odds of ST elevation resolution in addicts was 1.8 (95%, CI: 1.09-2.95) compared to non-addicts. When it was adjusted for other variables, it reduced to 1.03 (95%, CI: 0.54-1.97). CONCLUSION: There was not any significant relationship between opium addiction and response to thrombolytic therapy among patients with acute MI. Keywords: Acute myocardial infarction, opium, streptokinase, substance abuse.
2008
12
01
https://arya.mui.ac.ir/article_10060_331b2be224ea8a8a73ea2a4c821fefc4.pdf
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
WEIGHT LOSS REDUCES C- REACTIVE PROTEIN AND FIBRINOGEN LEVELS IN OBESE WOMEN
Narges
Tajik
Seyed Ali
Keshavarz
Mahmoud
Djalali
Hale
Sadrzadeh yeganeh
Mohammad Reza
Eshraghian
Maryam
Chamary
Abstract BACKGROUND: obesity is one of the most important risk factors in chronic diseases, like coronary heart disease and diabetes mellitus. It is believed that elevated levels of C- reactive protein (CRP) and fibrinogen are associated with increased cardiovascular risk. We examined the hypothesis that weight loss would reduce plasma CRP and fibrinogen levels in obese women. METHODS: Body weight, fasting glucose, insulin, triglyceride, total cholesterol, high- density lipoprotein cholesterol (HDL-C), low- density lipoprotein cholesterol (LDL-C) and acute phase proteins were measured at baseline and after 12 weeks of weight loss regimen in 29 obese women. RESULTS: Weight, BMI, fasting blood glucose, cholesterol and triglyceride had significant reductions. HDL-C had increased significantly. No significant changes were observed in LDL-C and insulin concentrations. Plasma acute phase proteins levels decreased significantly. CONCLUSION: Weight loss may represent an important intervention to reduce acute phase protein levels, which may mediate its cardioprotective effects in obese women. Keywords: Obesity, weight loss, acute phase proteins, cardiovascular disease, women.
2010
12
01
https://arya.mui.ac.ir/article_10061_a5efb94391ac390eb5cec632970326d0.pdf
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
IS THERE ANY DIFFERENCE BETWEEN DIETARY HABITS IN HYPER-TENSIVES, HYPERLIPIDEMICS, OBESE, SMOKER INDIVIDUALS AND THE NORMAL POPULATION?
Javed Hussain
Akhtar
Nizal
Sarrafzadegan
Noushin
Mohammadifard
Roya
Kelishadi
Zahra
Dana Siadat
Mojgan
Gharipour
Abstract BACKGROUND: Cardiovascular disease has been remained the leading cause of death worldwide. This study has been designed to comprise dietary habits of persons with cardiovascular disease (CVD) risk factors and those without them. METHOD AND MATERIALS: This cross-sectional study was performed on samples of a national community- based program for CVD prevention and control entitled Isfahan Healthy Heart Program (IHHP) including 12514 adults, aged≥ 19 years, 6391(51.1%) females and 6123(48.9%) males. All participants were interviewed by trained personnel who used a validated qualitative 48 item food frequency questionnaire (FFQ) to determine nutritional status. Blood pressure, serum lipids including triglycerides, total cholesterol, LDL-Cholesterol and HDL-Cholesterol, weight and height were measured and smoking habit was determined by a questionnaire. The frequency of food consumption of persons with and without the risk factors was compared by student t- test. The analysis was performed by SPSS version 11.5. RESULTS: Our results show that the prevalence of dyslipidemia, hypertension, smoking and obesity are 54%, 16.8%, 15.1% and 16.8%, respectively. Hypertensive and dyslipidemic subjects have significantly more frequent consumption of healthy foods (P < 0.05), in comparison to normotensive and normolipidemic whereas smokers and obese participants have a significantly higher consumption of unhealthy foods (P < 0.01) in comparison to non-smokes and the non-obese subjects. CONCLUSION: Our results showed that dyslipidemic and hypertensive individuals have more attention on their dietary habits. In contrast, obese and smoker persons have less attention to a healthy diet. Keywords: Hypertesion, Dyslipidemia, Obesity, Smoking, Nutrition, Adult.
2010
12
01
https://arya.mui.ac.ir/article_10062_61df5707f5e56bac4615d29d7d8ca1eb.pdf
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
ATHEROSCLEROSIS RISK FACTORS FREQUENCY AMONG NORTH AMERICANs AND IRANIANs STROKE CASES
Kavian
Ghandehari
Ashfaq
Shuaib
Abstract INTRODUCTION: Atherosclerosis of cerebral arteries is the most common etiology of ischemic stroke around the world. This pilot double-center study evaluated risk factors of atherosclerosis in stroke patients in two different racial subtypes. METHOD AND MATERIALS: This prospective clinical study was conducted on 100 consecutive stroke patients in Mackenzie hospital, Canada and 100 consecutive stroke patients in Ghaem hospital, Iran in 2007. The patients were age and sex matched. All of the Canadian patients were from white North American race and all of the Iranian patients were white Persian race. Diagnosis of ischemic stroke was made by stroke neurologists. The frequency rates of hypertension, diabetes, hypercholestrolemia and smoking were detected in the two studied groups. Chi-Square and Fisher tests served for statistical analysis and P < 0.05 was declared as significant. RESULTS: 92 males and 108 females with ischemic stroke were investigated. Hypertension was the most common risk factor of atherosclerosis in all patients followed by hypercholestrolemia, diabetes and smoking. The influence of race on the frequency rate of atherosclerosis risk factors was not significant, P > 0.05. Hypertension was significantly more frequent in Iranian than Canadian males: df = 1, P = 0.023. However, racial difference in the frequency rate of the hypertension was insignificant in the females: df = 1, P = 0.841. The effects of race on frequency rate of other atherosclerosis risk factors was insignificant in each gender separately, P > 0.05. CONCLUSION: There is no significant difference in frequency rate of atherosclerosis risk factors between North American and Persian stroke patients. Keywords: Atherosclerosis, Risk Factors, Stroke, Race.
2010
12
01
https://arya.mui.ac.ir/article_10063_6bba675a5c9e69bd6fa3267cc2f7d100.pdf
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
EFFECT OF SOY LECITHIN ON SERUM LIPID PARAMETERS OF HYPERLIPIDEMIC POSTMENOPAUSAL WOMEN REFERRING TO SHAHID FAGHIHEE HOSPITAL OF SHIRAZ UNIVERSITY OF MEDICAL SCIENCES
Sayed Mohammad Ali
Kooshesh
Shahryar
Eghtesadi
Mohammad Hassan
Eftekhari
Zahra
Saraf
Hamid
Haghani
Abstract BACKGROUND: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality throughout the world. Hyperlipidemia, as one of the main causes of CVD, has been diagnosed in nearly one third of Iranian middle aged women. Menopause manifests wide range of physiologic changes in women, most important of which is hyperlipidemia. Appropriate nutritional interventions can prevent or postpone some cardiovascular events in postmenopausal women. This randomized double blind clinical trial aimed to examine the effect of soy lecithin on serum lipid parameters of hyperlipidemic postmenopausal women. METHOD AND MATERIALS: Sixty free living postmenopausal women, aged 50-60 years, with mild to moderate hyperlipidemia entered the study. Subjects were randomly assigned in one of three treatments: yogurt; or: yogurt with 16g soy lecithin granules; or: yogurt with 10g sunflower oil, containing equal amount of linoleic acid and energy as the administered lecithin. Strawberry syrup was added to ensure blindness. To assess the effects of confounding factors, BMI and waist circumference were measured. Intake of some dietary factors (energy, macronutrients, saturated fatty acids, monounsaturated fatty acids, polyunsaturated fatty acids, cholesterol, calcium and fiber) were assessed using 24 hr-food recall and 3-day food record questionnaires. Changes in physical activity level were assessed by seven day-physical activity recall questionnaire. Serum lipid parameters (TC, Non-HDL.C, LDL.C, HDL.C and TG) were measured twice at baseline and 4 weeks of treatment. RESULTS: There was no significant difference between treatment groups, but a significant decrease was found within the intervention group (lecithin) in the average level of TC (252.33 ± 24.02 vs. 255.22 ± 24.82 mg/dl and P = 0.02), LDL.C/HDL.C (3.99 ± 0.50 vs. 4.17 ± 0.56 mg/dl and P = 0.001) and Non.HDL.C (211.94 ± 23.94 vs. 216.00 ± 23.73 mg/dl and P = 0.005) and accompanying significant increase in serum HDL.C level (40.39 ± 5.21 vs. 39.22 ± 5.58 mg/dl and P = 0.04). Likewise, no significant change was found in serum lipid profile within the control group І (sunflower oil). Decreasing LDL.C/HDL.C level (4.18 ± 0.40 vs. 4.24 ± 0.43 mg/dl and P = 0.03) was the only significant change in serum lipid profile of control group ІІ (yogurt). CONCLUSION: Soy lecithin treatment had no significant hypocholesterolemic effect on serum lipid profile, in a way that we can not claim any independent effect for lecithin's linoleic acid content. Keywords: soy lecithin, hyperlipidemic, menopause, linoleic acid, lipid profile.
2008
12
01
https://arya.mui.ac.ir/article_10064_30e99a003b49b8326d6858075df2f104.pdf
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
BODY IRON STORES AND OXIDATIVE STRESS MARKERS IN WOMEN OF REPRODUCTIVE AGE: IS IT RELATED TO ATHEROSCLEROSIS?
Farshad
Amirkhizi
Fereydoun
Siassi
Sara
Minaie
Mahmoud
Djalali
Maryam
Chamari
Abstract BACKGROUND: Elevated body iron stores have been suggested to be a risk factor for cardiovascular disease (CVD). We examined whether elevated plasma ferritin concentrations as indicator of iron stores, affect the oxidative stress markers in a reproductive age women population. METHOD: One hundred sixty, 20-45-year-old women were randomly selected. We investigated body iron stores by measuring the concentrations of plasma ferritin. Furthermore, we assessed oxidative stress markers by measuring the concentrations of plasma malondialdehyde (MDA) and activities of erythrocyte cytoprotective enzymes, including superoxide dismutase (CuZn-SOD), catalase (CAT) and glutathione peroxidase (GPX) in a random sample of cardiovascular disease-free women in reproductive age. RESULTS: Subjects in the highest tertile of plasma ferritin presented the highest levels of plasma MDA (p<0.001) and CAT activity (P < 0.05). Furthermore, these Subjects presented the lowest levels of CuZn-SOD activity (P < 0.01). No significant associations were found between the tertile of plasma ferritin in GPX activity. Plasma ferritin was significantly directly associated with plasma MDA levels and inversely associated with CuZn-SOD activity. Using multiple regression, Plasma ferritin levels was positively correlated with MDA levels and inversely correlated with CuZn-SOD activity. CONCLUSION: Our findings revealed an association between body iron stores and oxidative stress markers linked to atherosclerosis process. The results emphasize that iron overload would elevate the risk of coronary artery disease by promoting the lipid peroxidation. Keywords: Iron stores, ferritin, oxidative stress, atherosclerosis, women, reproductive age.
2010
12
01
https://arya.mui.ac.ir/article_10065_4fd1468499c0632d56c74d0967d7d53c.pdf
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
SUCCESS RATE OF PERCUTANEOUS CORONARY INTERVENTION IN PATIENTS WITH CHRONIC TOTAL OCCLUSION OF CORONARY ARTERIES
Mashallah
Dehghani
Homa
Falsoleiman
Sayed Mohammad Reza
Moosavi
Abstract BACKGROUND: Chronic total occlusion of coronary arteries (CTO) remains one of the most challenging lesion subsets in interventional cardiology even with the development of medical devices and operator expertise. This study sought to determine the overall success rate of percutaneous coronary intervention (PCI) for this lesion in the center and to examine the relationship between variables such as patients’ characteristics, clinical risk factors, lesion characteristics and procedural success rate. METHODS: Clinical and coronary angiographic data of 58 patients with CTO who underwent PCI between May 2004 and November 2006 in Ghaem Hospital were retrospectively analyzed. A P value of less than 0.05 was considered statistically significant. Analyses were performed using the software packages SPSS (11.5 version). RESULTS: In this study, there were 58 CTO lesions in 41 men (70.7%) and 17 women (29.3%) with a mean occlusion time of 5 months. The overall success rate of PCI was 77.6%. There was no significant correlation between the success rate of PCI and the patient’s age, sex, clinical risk factors, history of recent MI and duration of occlusion (P > 0.05). The success rate was not affected by target vessel, location of lesion, presence of stump, presence of side branch at the site of occlusion and TIMI flow of artery (P > 0.05). The success rate of PCI was decreased with increase in the length of occlusion and presence of bridging collaterals (P < 0.05). CONCLUSION: The length of occlusion and presence of bridging collaterals affected the success rate adversely. Whereas the patients’ characteristics, clinical risk factors and other characteristics of coronary artery lesion had no statistically significant effect on success rate of PCI. Despite the technical difficulty of PCI in CTO lesions, this procedure can be done safely with relatively high success rate. Keywords: Chronic total occlusion (CTO), percutaneous coronary intervention (PCI), coronary arteries.
2008
12
01
https://arya.mui.ac.ir/article_10066_c3dc8b8f2f83441acde0c9af0f6f7700.pdf
ARYA Atherosclerosis Journal
ARYA
1735-3955
1735-3955
2008
4
3
Pasar Ayam Buras Tetap Terjamin
Yudi
Anto
Ayam buras menjadi salah satu komoditas peternakan yang gencar dikembangkan pemerintah. Sedikitnya lima proyek pengembangan produksi ternak ayam buras telah digulirkan.Bagaimana peluang pemasaran ayam buras di masa datang, dan apa saja kendala pengembangannya, dibeberkan Dirjen Peternakan, DR. Ir. Sofyan Soedardjat, MS kepada wartawan Trubus Fendy R. Paimin dan Syah Angkasa di ruang kerjanya. Berikut petikan wawancaranya
agronomy
horticulture
livestock
2010
12
01