TY - JOUR ID - 10768 TI - Association of cardiac enzymes with morbidity and mortality of patients undergoing coronary endarterectomy surgery JO - ARYA Atherosclerosis Journal JA - ARYA LA - en SN - 1735-3955 AU - Heydari, Aghigh AU - Sabzi, Feridoun AU - Asadmobini, Atefeh AU - Eskandari, Soudabeh AD - Cardiovascular Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran AD - Department of Biostatistics and Epidemiology, School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, Iran Y1 - 2022 PY - 2022 VL - 17 IS - 1 SP - 1 EP - 5 KW - Biomarkers KW - Coronary Artery Bypass, Off-Pump KW - Creatine Kinase, MB Form KW - Endarterectomy KW - Troponin DO - 10.22122/arya.v17i0.2085 N2 - BACKGROUND: The relationship between cardiac enzyme release following coronary endarterectomy (CE) and morbidity and mortality is unclear. Therefore, the present study aimed to investigate the association of cardiac enzymes with morbidity and mortality of patients undergoing CE surgery.METHODS: This was a single-center retrospective cohort study of 475 patients who had undergone off-pump coronary artery bypass graft (OPCABG). The patients were followed up for a mean of 72.99 ± 14.60 months.RESULTS: Among 475 patients undergoing OPCABG, 39 (8.2%) were non-survivors. Non-survivors were younger and had a fewer ejection fraction (EF). Comorbidities were similar in survivors and non-survivors. The crude Cox regression analysis showed that creatine kinase-myocardial band (CK-MB) had a protective effect against mortality, but when adjusted with age, sex, diabetes mellitus (DM), hypertension (HTN), hyperlipidemia, smoking, family history, body mass index (BMI), left main disease (LMD), and EF, this effect disappeared. Troponin in crude and adjusted analysis did not have any significant effect.CONCLUSION: There is no association between CK-MB and troponin and mortality in patients undergoing coronary artery bypass graft (CABG). UR - https://arya.mui.ac.ir/article_10768.html L1 - https://arya.mui.ac.ir/article_10768_7920661190325c4b0b39e29b4f8dc9f0.pdf ER -