TY - JOUR ID - 10459 TI - Randomized controlled trial on the effects of legumes on cardiovascular risk factors in women with abdominal obesity JO - ARYA Atherosclerosis Journal JA - ARYA LA - en SN - 1735-3955 AU - Safaeiyan, Abdolrasoul AU - Pourghassem-Gargari, Bahram AU - Zarrin, Rasoul AU - Fereidooni, Javid AU - Alizadeh, Mohammad AD - Department of Vital Statistics and Epidemiology, School of Health, Tabriz University of Medical Sciences, Tabriz, Iran AD - Professor, Nutrition Research Center AND Department of Biochemistry and Dietetics, School of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran AD - Assistant Professor, Food and Beverages Safety Research Center AND Department of Nutrition, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran AD - Assistant Professor, Department of English language, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran Y1 - 2015 PY - 2015 VL - 11 IS - 2 SP - 117 EP - 125 KW - Legume KW - Cardiovascular Disease KW - Caloric Restriction KW - Central Obesity KW - Premenopause DO - N2 - BACKGROUND: The effect of legume-based hypocaloric diet on cardiovascular disease (CVD) risk factors in women is unclear. This study provides an opportunity to find effects of high-legume diet on CVD risk factors in women who consumed high legumes at baseline. METHODS: This randomized controlled trial was undertaken in 34 premenopausal women with central obesity. After 2 weeks of a run-in period on an isocaloric diet, subjects were randomly assigned into two groups: (1) hypocaloric diet enriched with legumes (HDEL) (n = 17) (two servings per day) and (2) hypocaloric diet without legumes (HDWL) (n = 17) for 6 weeks. The following variables were assessed before intervention, 3, and 6 weeks after it: Waist to hip ratio (WHR), total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-sensitive-C-reactive protein (hs-CRP), total antioxidant capacity (TAC), nitric oxides (NOx), and Malondialdehyde (MDA). RESULTS: Both hypocaloric diets reduced hs-CRP in 3 weeks and returned it to basal values after 6 weeks (P = 0.004). HDWL significantly reduced WHR [P = 0.010 (3.2%)] and increased TC [P < 0.001 (6.3%)]. Despite the significant effect of HDEL on increasing TAC in 3 weeks [P = 0.050 (4%)], the level of TAC remained the same in 6 weeks. None of the diets had any significant effects on NOx and MDA. CONCLUSION: The study indicated that beneficial effects of legumes on TC, LDL-C, and hs-CRP were achieved by three servings per week, and consuming more amounts of these products had no more advantages.    UR - https://arya.mui.ac.ir/article_10459.html L1 - https://arya.mui.ac.ir/article_10459_a6d942cb274a647fe74c6772d609bbb2.pdf ER -