Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
2251-6638
5
4
2010
11
30
EFFECT OF CARDIAC REHABILITATION ON FUNCTIONAL CAPACITY OF PATIENTS AFTER CARDIAC SURGERY BY ASSESSING 6-MINUTE WALKING TEST
EN
Fatemeh
Steki Ghashghaei
MS Student, Exercise Physiology, Khorasgan Azad University, Isfahan Cardiovascular Research Center, Isfahan.
f.f.ghashghaei@gmail.com
Farzaneh
Taghian
PHD, Professor of Exercise Physiology, Khorasgan Azad University, Isfahan.
Jamshid
Najafian
0000-0002-1472-1218
MD, Cardiologist, Isfahan Cardiovascular Research Center, Isfahan.
jamshid_najafian@yahoo.com
Mohammad
Marandi
PHD, Professor of Exercise Physiology, Isfahan University, Isfahan.
Mohammad Arash
Ramezani
Expert of Cardiovascular Research Center, Isfahan Cardiovascular Research Center, Isfahan.
Samaneh
Moastafavi
Physician of Cardiac Rehabilitation Center, Isfahan Cardiovascular Research Center, Isfahan.
Katayon
Rabiei
Expert of Cardiovascular Research Center, Isfahan Cardiovascular Research Center, Isfahan.
Abstract BACKGROUND: Cardiac rehabilitation is a well-established treatment for patients with coronary artery disease and it is beneficial for cardiac patients. It improves functional capacity and modifies risk factors of coronary artery disease such as hypertension, arrhythmia and others. The aim of this study was to investigate the effects of cardiac rehabilitation on functional capacity of patients after cardiac surgery by using the six-minute walking test which is a simple and well-tolerated test for cardiac patients compared with other stress tests. METHODS: Thirty two patients were selected for this study. All patients had cardiac surgery, two months before admission. These samples allocated to two groups. Interventional group (n = 17, mean age: 62 ± 12 years) completed the cardiac rehabilitation programs for two months but, reference group (n = 15, mean age: 58.5 ± 12.5 years) didn't have any physical activity during this period. At the beginning of study, functional capacity of patients was evaluated by exercise test and six-minute walking test. After two months of cardiac rehabilitation, functional capacity was evaluated for the second time in each group. Cardiac rehabilitation consisted of exercise, nutritional and psychological consultation and risk factor management. Data were analyzed with SPSS software version 15. For comparing the mean of outcomes in repeating measures, the repeated ANOVA model was used. RESULTS: A Significant improvement was observed in the interventional group compared to the reference group in walking distance (472.62 ± 19.29 m vs. 412.24 ± 20.54 m, respectively, P = 0.04). CONCLUSION: Cardiac rehabilitation significantly improves functional capacity and this evolution was shown by 6MWT which is an easy and safe and low cost test compared to other stress tests. Keywords: Cardiac Rehabilitation, Functional Capacity, Stress Test.
https://arya.mui.ac.ir/article_10019.html
https://arya.mui.ac.ir/article_10019_3f282d056f55743517e8c51665533ac1.pdf
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
2251-6638
5
4
2010
11
01
ANTHROPOMETRIC INDICES IN ASSOCIATION WITH CARDIOMETABOLIC RISK FACTORS: FINDINGS OF THE ISFAHAN HEALTHY HEART PROGRAM
EN
Nizal
Sarrafzadegan
Professor of Medicine, Isfahan Cardiovascular Research Center Isfahan.
Roya
Kelishadi
Associate Professor of Pediatrics, Pediatric Preventive Cardiology Department, Isfahan Cardiovascular Research Center, Isfahan Uni-versity of Medical Sciences, Isfahan.
kelishadi@med.mui.ac.ir
Alireza
Najafian
MD, Cardiologist, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Center, Isfahan.
Alireza
Khosravi
0000.0003.0736.2090
Cardiologist, Assistant Professor, Isfahan Cardiovascular Research Center, Isfahan.
alirezakhosravif@gmail.com
Ahmad
Bahonar
Executive Manager of Isfahan Cardiovascular Research Center (ICRC), WHO Collaborating Center, Isfahan University of Medical Sciences, Isfahan.
Sedigheh
Asgary
0000-0001-7724-4802
Associate Professor of Pharmacognosy, Isfahan Cardiovascular Research Center, Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan.
sedighehasgary@gmail.com
Gholamhossein
Sadri
PhD, Community Medicine, Research Management Office, Isfahan University of Medical Sciences, Isfahan.
Ahmad
Amani
General Practitionner, Markazi Province Health Center, Arak.
Babak
Eshrati
Epidemiologist, Markazi Province Health Center, Arak.
Abstract BACKGROUND: Obesity is increasing worldwide, but the debate about the most valid index associated with its health hazards remains unresolved. This study aimed to compare four main anthropometric indices by gender, to determine the best index in predicting cardiometabolic risk factors and to find their cutoff values in the population studied. METHODS: This study was a cross-sectional community-based study performed on a representative sample of 12,514 adults (aged ≥19 years) selected via 2-stage random cluster sampling from 3 cities in Iran. Partial correlation and ROC curve analyzes were used to determine the best anthropometric indices and their cutoff values. RESULTS: The study population comprised 6123 males and 6391 females. In both genders, waist circumference (WC) had the highest correlation with cardiometabolic risk factors (6 of 8 risk factors in men and 7 of 8 risk factors in women). ROC analyses showed that in males, the largest area under curve (AUC) was obtained for waist-to-stature ration (WSR) in most risk factors (6 of the 10) followed by body mass index (BMI) and waist-to-height ratio (WHR) with largest AUC (3 of the 10). The corresponding figure for females was obtained for WSR (9 of the 10) followed by BMI and WHR (1 of 10). Optimal cutoff values computed for combination of 3 major risk factors (including diabetes mellitus, hypertension and dyslipidemia) revealed that in males and females, respectively, the cutoff values were 21.9 and 23.5 kg/m2 for BMI, 80.70 and 84.70 cm for WC, 0.85 and 0.86 for WHR and 0.47 and 0.53 for WSR. CONCLUSION: WSR could be a valid anthropometric index for predicting cardiometabolic risk factors, and it has less variation than other indices among populations with ethnic differences in body size and fat distribution. Keywords: Anthropometry, Cardiovascular Risk Factors, Iran, Obesity.
https://arya.mui.ac.ir/article_10020.html
https://arya.mui.ac.ir/article_10020_3599561d8d99d9e808658e0c0c86c130.pdf
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
2251-6638
5
4
2010
11
30
VALIDATION OF THE CHILD AND ADOLESCENT INTERNATIONAL PHYSICAL ACTIVITY QUESTIONNAIRES IN IRANIAN CHILDREN AND ADOLESCENTS
EN
Zahra
Faghihimani
MD, Research Assistant, Department of Pediatric Preventive Cardiology Department, Isfahan University of Medical Sciences, Isfahan.
Mojhgan
Nourian
PhD Student, Community Nutrition, Lecturer, Department of Nutrition, Isfahan University of Medical Sciences, Isfahan.
Amir Hossein
Nikkar
MD, Research Assistant, Department of Pediatric Preventive Cardiology Department, Isfahan University of Medical Sciences, Isfahan.
Ziba
Farajzadegan
MD, Associate Professor of Community Medicine, Isfahan University of Medical Sciences, Isfahan.
Nooshin
Khavariyan
MD, Research Assistant, Department of Pediatric Preventive Cardiology Department, Isfahan University of Medical Sciences, Isfahan.
Shohreh
Ghatrehsamani
MD, Research Assistant, Department of Pediatric Preventive Cardiology Department, Isfahan University of Medical Sciences, Isfahan.
Parinaz
Poursafa
MSc, Research Assistant, Pediatric Preventive Cardiology Department, Isfahan University of Medical Sciences, Isfahan.
Roya
Kelishadi
MD, Associate Professor of Pediatrics, Pediatric Preventive Cardiology Department, Isfahan University of Medical Sciences, Isfahan.
kelishadi@med.mui.ac.ir
Abstract BACKGROUND: With reference to the importance of physical activity during childhood and adolescence in their health promotion and prevention of chronic diseases during adulthood, it is necessary to have a reliable and valid method for evaluating physical activity level in this age group. Physical activity questionnaire child (PAQ-C) and adolescents (PAQ-A) have been designed for this purpose. This study aimed to validate these questionnaires in a representative sample of Iranian children and adolescents. METHODS: After translating the PAQ-C and PAQ-A to Persian, the face and content validities of these questionnaires were assessed by a committee of experts of different specialties including specialists in pediatrics, community medicine, social specialist and sport medicine. After minor modification of some items of the questionnaires according to the available types of physical activity and the socio-cultural conditions, the final questionnaires were prepared. Thereafter, 82 children and adolescents with 8 to 18 years of age completed the questionnaires. RESULTS: To assess the questionnaire reliability Iranian students and the validity accreditation was modified and got from the committee. A Cronbach’s alpha of 0.894 was produced at the end of the analysis showing it has been reliable for this population. CONCLUSION: According to the results found in this survey, PAQ questionnaire can be used as a reliable and valid method for next studies; so health planning based on Iranian students’ physical activity will be possible in future. Keywords: Physical Activity Questionnaire, Reliability, Validity.
https://arya.mui.ac.ir/article_10021.html
https://arya.mui.ac.ir/article_10021_bbee494eab988e0c045ea8fe34eb018b.pdf
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
2251-6638
5
4
2010
11
01
LATE TREATMENT WITH L-ARGININE INCREASES 8-ISOPROSTAGLANDIN F2Α AND OXIDIZED LDL IN HYPERCHOLESTEROLEMIC RABBITS
EN
Motaharsadat
Hosseini
Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan.
Shaghayegh
Haghjooy Javanmard
0000-0002-3853-5006
Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan.
sh_haghjoo@med.mui.ac.ir
Mehdi
Nematbakhsh
Applied Physiology Research Center, Isfahan University of Medical Sciences, Isfahan.
Abstract BACKGROUND: The role of L-arginine, the precursor of nitric oxide, on the oxidative stress and atherosclerosis has been previously studied; it has had inconsistent beneficial effects. The aim of this study was to investigate whether administration of L-arginine reduces oxidative stress and the progression of atherosclerosis in cholesterol fed rabbits. METHODS: Eighteen white male rabbits were randomized into three groups. All of them received 1% high cholesterol diet for the first four weeks and normal diet for the second four weeks of the experiment. The early treatment (ET) group received L-arginine (3% in drinking water) in the first four weeks while the late treatment (LT) group received L-arginine for the second four weeks of the experiment. Control (C) group received no L-arginine. The plasma levels of lipids, 8-isoprostaglandin F2α, CRP and oxLDL were measured before, and at 4th and 8th weeks of the experiment. Aorta fatty streak formation was measured at the end of the experiment. RESULTS: The plasma levels of lipids were increased significantly during the first 4 weeks and decreased significantly during the second 4 weeks with no significant differences between the groups. The plasma concentration of 8-isoprostaglandin F2α was significantly decreased in the ET group compared with the C group at the end of the experiment. The fatty streak formation in the ET group was significantly lower than that in the C group at the end of the experiment. The plasma concentration of CRP significantly increased after 4 weeks administration of hypercholesterolemic diet in all groups. Also, its amount was significantly smaller in ET group in comparison with other groups. The plasma concentration of oxLDL decreased significantly in the ET group compared with LT group at the end of the experiment. However, the plasma concentration of oxLDL increased in the C group and in the LT group at the end of the experiment. CONCLUSION: L-arginine therapy from the very beginning of hypercholesterolemia reduced oxidative stress and the consequential irreversible vascular damage, and may be useful for primary prevention. Keywords: Atherosclerosis, Oxidized Low Density Lipoproteins, Oxidative Stress, 8-Isoprostaglandin F2α, L-Arginine, Nitric Oxide.
https://arya.mui.ac.ir/article_10022.html
https://arya.mui.ac.ir/article_10022_853702a7db0b923f19c895bb90fd1564.pdf
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
2251-6638
5
4
2010
11
01
RELATIONSHIPS OF SERUM LEPTIN CONCENTRATION WITH INSULIN, GLUCOSE, HbA1c LEVELS AND INSULIN RESISTANCE IN OVERWEIGHT POST-MENOPAUSAL DIABETIC WOMEN
EN
Maryam
Taghdir
MS, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran.
Abolghasem
Djazayeri
PhD, Professor of Nutrition, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran.
jazaiers@tums.ac.ir
Mahmoud
Djalali
PhD, Professor of Biochemistry, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran.
Mohammadreza
Eshraghian
PhD, Associate Professor, Department of Biostatistics, School of Health, Tehran University of Medical Sciences, Tehran.
Asadollah
Rajab
MD, Endocrinologist, Iranian Diabetes Society, Tehran.
Haleh
Sadrzade Yegane
MS, Instructor, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran.
Mahkameh
Ashourpour
MS, Department of Nutrition and Biochemistry, School of Health, Tehran University of Medical Sciences, Tehran.
Mojtaba
Sepandi
MS, Instructor, Department of Epidemiology and Biostatistics, School of Health, Jondishapour University of Medical Sciences, Ahwaz.
Abstract BACKGROUND: Leptin, the product of the ob gene, could have a role in the pathogenesis of obesity and non-insulin dependent diabetes mellitus (NIDDM). The aim of this study was to investigate relationships between serum leptin concentration and insulin, glucose, HbA1c levels and insulin resistance in diabetic women. METHODS: We studied 45 diabetic women and 45 healthy women (controls) who aged 45-60 years and had BMI of 25-30 kg/m2. Serum leptin, insulin, HbA1c, fasting blood sugar and insulin resistance were determined in the two groups. RESULTS: There was a significant positive correlation between leptin and insulin (r = 0.295, P = 0.049) and insulin resistance (r = 0.329, P = 0.027) in controls but non-significant correlation between leptin and HbA1c and fasting blood sugar were observed in the two groups. CONCLUSION: This study did not document any significant relationship between serum leptin and insulin, glucose, HbA1c and insulin resistance in diabetic women. Keywords: Type 2 Diabetes Mellitus, Leptin, Insulin.
https://arya.mui.ac.ir/article_10023.html
https://arya.mui.ac.ir/article_10023_8bd63da526b884d4518ce85f6054065d.pdf
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
2251-6638
5
4
2010
11
30
COMPARISON OF FOOD HABITS AMONG SMOKER AND NON-SMOKER INDIVIDUALS: ISFAHAN HEALTHY HEART PROGRAM
EN
Firoozeh
Sajadi
BS in Nutrition, Nutrition Department, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan.
firoozehsajjasdi2002@yahoo.com
Niloofar
Ghaderian
BS in Nutrition, Nutrition Department, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan.
Noushin
Mohammadifard
0000-0003-1776-1060
MSc in Nutrition, Nutrition Department, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan.
nmohammadifard@gmail.com
Maryam
Maghroon
BS in Nutrition, Nutrition Department, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan.
Hasan
Alikhasi
BS in Nutrition, Nutrition Department, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan.
Hamid
Roohafza
MD, Psychiatrist, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan.
Ahmad
Bahonar
MD, NPH, Executive Manager, Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan.
Mohamadreza
Rahmati
BSc in Public Health, Markazi Provincial Health Center, Arak University of Medical Sciences, Arak.
Behrooz
Salavati
BSc in Public Health, Isfahan Provincial Health Center, Isfahan University of Medical Sciences, Isfahan.
Abstract BACKGROUND: Cigarette smoking is an important risk factor of various chronic diseases. Smokers also seem to make a lifestyle which is different from those of non-smokers. This study was conducted to compare dietary habits of smoker and non-smoker individuals. METHODS: This cross-sectional study was conducted in 2000-2001 in Isfahan and Najaf-Abad counties. Sample size was 6300 individuals aged ≥ 19 year old. The individuals' food habits were assessed by using a food frequency questionnaire. RESULTS: Smokers' consumption of some foods, including whole diary products, was higher than that of non-smokers (P = 0.001). Also, the frequency consumption of hydrogenated oil and liquid oil in smoker men and non-smoker ones was 6.9 ± 4.2, 6.5 ± 4.3, 2.2 ± 2.6 and 2.7 ± 2.4, respectively (P = 0.001). Mean consumption of fast food in smoker men was higher than non-smokers (1 ± 1.4 vs. 0.8 ± 1.5, respectively, P = 0.01). Non-smoking men's mean intake of fruit and vegetables was higher than that of smokers (11.7 ± 6 vs. 11± 6, respectively, P = 0.01). CONCLUSION: The results showed that smokers have an unhealthier dietary pattern than non-smokers; so, this is reflected in their unhealthy food choices, e.g. greater consumption of food products with high levels of saturated fat and cholesterol. Smoking and unhealthy dietary behavior have synergistic effects on incidence of non-communicable diseases. Broad interventions are required in the community towards tobacco consumption control and lifestyle modification in smokers. Keywords: Smoking, Food Habits, Cardiovascular Disease.
https://arya.mui.ac.ir/article_10024.html
https://arya.mui.ac.ir/article_10024_c6dba8aa8d4d99aba95c3dbd68a3dc95.pdf
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
2251-6638
5
4
2010
11
30
PREVALENCE AND SEVERITY OF CORONARY ARTERY DISEASE AMONG HYPERTENSIVE AND NORMOTENSIVE PATIENTS
EN
Fariborz
Akbarzadeh
MD, Associated Professor of Cardiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz.
s_akbarzadeh@yahoo.com
Leila
Pourafkari
MD, Resident of Cardiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz.
Seyed Mohammad
Hashemi Jazi
MD, Associated Professor of Cardiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan.
Leila
Hesami
Medical Student, School of Medicine, Tabriz University of Medical Sciences, Tabriz.
Valliollah
Habibi
MD, Cardiac Surgery Fellow, School of Medicine, Tabriz University of Medical Sciences, Tabriz.
Abstract BACKGROUND: Treatment of hypertension (HTN) as an important risk factor of coronary artery disease (CAD) is for prevention of its mortality. The aim of the present study was to investigate risk factor distribution, prevalence and severity of CAD among hypertensive and normotensive patients undergoing elective coronary angiography in Tabriz Madani Heart Center. METHODS: In a descriptive cross-sectional study, 976 out of 3000 patients who underwent coronary angiography (CAG) between February 1, 2005 and February 1, 2006 were randomly selected to enter the study. Demographic and angiographic data were collected. Data entry and analysis was done by SPSS software version 11.5 and EPI software version 6.4. RESULTS: Prevalence of hypertension in patients who underwent coronary angiography was 60.5%. Prevalence of CAD was 84% and 87% in hypertensive and normotensive patients, respectively (P = 0.2). Prevalence of diabetes mellitus and hyperlipidemia were more frequent in hypertensive patients (P = 0.001). Although the prevalence of 3-vessel disease was higher in hypertensive patients (32% vs. 28%) the difference was not significant statistically. The difference in prevalence of CAD among hypertensive and normotensive men was not statistically significant (91% and 92%, respectively); but this difference among women was statistically meaningful (78% vs. 63%, p = 0.01). 3-vessel disease in hypertensive women was more frequent than normotensive women (37% vs. 18%, P = 0.02). CONCLUSION: With regard to high prevalence of cardiac risk factors and severe CAD in hypertensive patients, prompt health measures are needed for control of hypertension in general population especially in the hypertensive women. Keywords: Hypertension, Coronary Artery Disease, Risk Factors.
https://arya.mui.ac.ir/article_10025.html
https://arya.mui.ac.ir/article_10025_9a4357bdefcddceeffd0720518eee670.pdf
Cardiovascular research institute, Isfahan University of Medical Sciences
ARYA Atherosclerosis Journal
1735-3955
2251-6638
5
4
2010
11
01
ASSESSMENT OF CAROTID ENDARTERECTOMY IN A SAMPLE OF IRANIAN PATIENTS
EN
Kavian
Ghandehari
MD FLSP, Professor of Cerebrovascular Disease, Mashhad University of Medical Sciences, Mashhad.
kavianghandehari@yahoo.com
Hadi
Modaghegh
MD, Professor of Vascular Surgery, Mashhad University of Medical Sciences, Mashhad.
Abstract BACKGROUND: Carotid endarterectomy (CEA) is recommended in patients with symptomatic and some times asymptomatic carotid stenosis in vascular surgery centers with low perioperative complication rate. METHODS: A stenosis retrospective study was carried out in patients underwent CEA in 3 vascular surgery centers in Tehran and 2 centers in Mashhad. Patients’ selection criteria, methods of detection of carotid stenosis, method of anesthesia, surgical techniques and perioperative complications were evaluated. RESULTS: Overall, 388 CEA in 345 patients (65% males) with mean age of 66.8 year old (ranged 46-84 years) were evaluated. Detection of carotid stenosis was made by one carotid duplex ultrasound in 90% of CEA candidates. The whole perioperative stroke death rate in reported Iranian vascular surgery centers is 6.4%. Perioperative stroke death rate in Imam Reza, Razavi, Shohaday Tajrish, Taleghani and Iranmehr hospitals was 2.4, 0, 4.8, ,10.2 and 10.2 percent, respectively. CONCLUSION: In Iran, CEA is recommended only in patients with symptomatic ≥ 70% internal carotid arterystenosis and preferably in patients with symptomatic ≥ 90% stenosis. Method of detection of carotid stenosis in Iranian vascular surgery centers should be corrected. Keywords: Carotid, Endarterectomy, Iran.
https://arya.mui.ac.ir/article_10026.html
https://arya.mui.ac.ir/article_10026_2bef7c0a253bacce752dcd5a98e1db45.pdf