ORIGINAL_ARTICLE
Randomized controlled trial on the effects of legumes on cardiovascular risk factors in women with abdominal obesity
BACKGROUND: The effect of legume-based hypocaloric diet on cardiovascular disease (CVD) risk factors in women is unclear. This study provides an opportunity to find effects of high-legume diet on CVD risk factors in women who consumed high legumes at baseline. METHODS: This randomized controlled trial was undertaken in 34 premenopausal women with central obesity. After 2 weeks of a run-in period on an isocaloric diet, subjects were randomly assigned into two groups: (1) hypocaloric diet enriched with legumes (HDEL) (n = 17) (two servings per day) and (2) hypocaloric diet without legumes (HDWL) (n = 17) for 6 weeks. The following variables were assessed before intervention, 3, and 6 weeks after it: Waist to hip ratio (WHR), total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-sensitive-C-reactive protein (hs-CRP), total antioxidant capacity (TAC), nitric oxides (NOx), and Malondialdehyde (MDA). RESULTS: Both hypocaloric diets reduced hs-CRP in 3 weeks and returned it to basal values after 6 weeks (P = 0.004). HDWL significantly reduced WHR [P = 0.010 (3.2%)] and increased TC [P < 0.001 (6.3%)]. Despite the significant effect of HDEL on increasing TAC in 3 weeks [P = 0.050 (4%)], the level of TAC remained the same in 6 weeks. None of the diets had any significant effects on NOx and MDA. CONCLUSION: The study indicated that beneficial effects of legumes on TC, LDL-C, and hs-CRP were achieved by three servings per week, and consuming more amounts of these products had no more advantages.
https://arya.mui.ac.ir/article_10459_a6d942cb274a647fe74c6772d609bbb2.pdf
2015-03-07
117
125
Legume
Cardiovascular Disease
Caloric Restriction
Central Obesity
Premenopause
Abdolrasoul
Safaeiyan
1
Department of Vital Statistics and Epidemiology, School of Health, Tabriz University of Medical Sciences, Tabriz, Iran
AUTHOR
Bahram
Pourghassem-Gargari
2
Professor, Nutrition Research Center AND Department of Biochemistry and Dietetics, School of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran
AUTHOR
Rasoul
Zarrin
3
Assistant Professor, Food and Beverages Safety Research Center AND Department of Nutrition, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
AUTHOR
Javid
Fereidooni
4
Assistant Professor, Department of English language, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
AUTHOR
Mohammad
Alizadeh
alizade85@yahoo.com
5
Assistant Professor, Food and Beverages Safety Research Center AND Department of Nutrition, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
LEAD_AUTHOR
ORIGINAL_ARTICLE
Comparing the effect of whole body massage by a specialist nurse and patients’ relatives on blood cortisol level in coronary patients
BACKGROUND: Cardiovascular diseases such as acute coronary syndrome and myocardial infarction are often accompanied by severe anxiety over the likelihood of death. Cortisol has been known as a stress hormone. However, there are controversies about the effect of massage therapy on blood cortisol level. Furthermore, no study is available on the difference between massage applied by a nurse specialist or by patients’ relatives on blood cortisol level. This study was aimed to compare the effect of massage applied by a nurse specialist and patients’ relatives on blood cortisol level among the patients admitted in coronary care unit (CCU). METHODS: In a randomized controlled trial, ninety patients hospitalized at CCU were randomly placed in three groups: massage by a nurse; massage by patients’ relatives and control group. The two massage groups received a session of whole body massage. The control group received the routine care. Data were analyzed using analysis of variance, chi-square and Fischer exact tests, Kruskal–Wallis and Wilcoxon Signed Ranks tests. RESULTS: The mean age of participants was 58.43 ± 14.23 years. None of the participants had the history of massage therapy. In the group massaged by a nurse, the median blood cortisol level was 281.90 nanomoles, which were decreased to 197.00 after the intervention (P < 0.007). The median blood cortisol level in the group massaged by the patients’ relatives and the control group did not affect significantly. CONCLUSION: Massage therapy decreased the blood cortisol level in the group that received massage by a specialist nurse. It can be recommended that massage therapy be used in patients admitted in CCU.
https://arya.mui.ac.ir/article_10460_f94c6458afc8b7c822e4baa9db748ba2.pdf
2015-03-01
126
132
Massage Therapy
Nurses
Relatives
Acute Coronary Syndrome
Myocardial Infarction
Cortisol
Mohsen
Adib-Hajbaghery
adib1344@yahoo.com
1
Professor, Trauma Nursing Research Center, Kashan University of Medical Sciences, Kashan, Iran
LEAD_AUTHOR
Rahman
Rajabi-Beheshtabad
2
Department of Nursing, Dehdash Imam Khomeini Hospital, Yasouj University of Medical Sciences, Yasouj, Iran
AUTHOR
Abolfazl
Arjmand
3
Assistant Professor, Physiology Research Center, Kashan University of Medical Sciences, Kashan, Iran
AUTHOR
ORIGINAL_ARTICLE
Inhibitory potential of pure isoflavonoids, red clover, and alfalfa extracts on hemoglobin glycosylation
BACKGROUND: Non-enzymatic glycosylation of hemoglobin is complications of diabetes. Antioxidant system imbalance can result in the emergence of free radicals’ destructive effects in the long-term. Red clover (Trifolium pratense L.) and alfalfa (Medicago sativa L.) contain isoflavonoids and have antioxidant activity. This experimental study evaluated the inhibitory activity of pure isoflavonoids (daidzein and genistein), red clover and alfalfa extracts on hemoglobin glycosylation. METHODS: This study was performed in Iran. Stock solution of hydroalcoholic extracts of red clover and alfalfa in concentrations of 1 and 10 g/100 ml and stock solution of daidzein and genistein in concentrations of 250 ng, 500 ng, 25 µg and 250 µg/100 ml were prepared as case groups. Control group was without hydroalcoholic extracts of plants and pure isoflavonoids. All experiments were performed in triplicate. Hemoglobin was prepared and antioxidant activities were investigated to estimate degree of nonenzymatic hemoglobin glycosylation. RESULTS: There was no significantly difference between used extracts (extract of red clover and alfalfa) and control of the hemoglobin glycosylation but using daidzein (P = 0.046, 0.029 and 0.021, respectively) and genistein (P = 0.034, 0.036 and 0.028) significantly inhibited (P < 0.050) this reaction in 25 µg/100 ml, 250 and 500 ng/100 ml concentrations when compared to control. in 25 µg/100 ml, 250 ng and 500 ng/100 ml concentrations percentage of inhibition were 32, 80 and 74.5% respectively with used of daidzein and were 21, 83 and 76% respectively with consumption of genistein. CONCLUSION: According to decrease of glycation of hemoglobin with isoflavonoids, two used plant in this study containing isoflavonoid may be useful on diabetes.
https://arya.mui.ac.ir/article_10461_24e3593114b351f171f18bfadaab0ae5.pdf
2015-03-07
133
138
Glycosylation
Genistein
Medicago sativa
Trifolium
Mohsen
Hosseini
1
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Sedigheh
Asgary
sedighehasgary@gmail.com
2
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
LEAD_AUTHOR
Somayeh
Najafi
s.najafi.bio@gmail.com
3
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
ORIGINAL_ARTICLE
Validation of a simplified food frequency questionnaire for the assessment of dietary habits in Iranian adults: Isfahan Healthy Heart Program, Iran
BACKGROUND: Dietary assessment is the first step of dietary modification in community-based interventional programs. This study was performed to validate a simple food frequency questionnaire (SFFQ) for assessment of selected food items in epidemiological studies with a large sample size as well as community trails. METHODS: This validation study was carried out on 264 healthy adults aged ≥ 41 years old living in 3 district central of Iran, including Isfahan, Najafabad, and Arak. Selected food intakes were assessed using a 48-item food frequency questionnaire (FFQ). The FFQ was interviewer-administered, which was completed twice; at the beginning of the study and 2 weeks thereafter. The validity of this SFFQ was examined compared to estimated amount by single 24 h dietary recall and 2 days dietary record. Validation of the FFQ was determined using Spearman correlation coefficients between daily frequency consumption of food groups as assessed by the FFQ and the qualitative amount of daily food groups intake accessed by dietary reference method was applied to evaluate validity. Intraclass correlation coefficients (ICC) were used to determine the reproducibility. RESULTS: Spearman correlation coefficient between the estimated amount of food groups intake by examined and reference methods ranged from 0.105 (P = 0.378) in pickles to 0.48 (P < 0.001) in plant protein. ICC for reproducibility of FFQ were between 0.47-0.69 in different food groups (P < 0.001). CONCLUSION: The designed SFFQ has a good relative validity and reproducibility for assessment of selected food groups intake. Thus, it can serve as a valid tool in epidemiological studies and clinical trial with large participants.
https://arya.mui.ac.ir/article_10462_72c99ef7e58d059ab64e289eb71dbb5e.pdf
2015-03-07
139
146
Validity
Reliability
Food Frequency Questionnaire
Dietary Intake
Food
Noushin
Mohammadifard
nmohammadifard@gmail.com
1
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
LEAD_AUTHOR
Firouzeh
Sajjadi
2
Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Maryam
Maghroun
maghroun@mailinator.com
3
Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Hassan
Alikhasi
4
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Farzaneh
Nilforoushzadeh
5
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Nizal
Sarrafzadegan
6
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
ORIGINAL_ARTICLE
Echocardiographic changes after aortic valve replacement: Does the failure rate of mitral valve change?
BACKGROUND: Since some degrees of functional mitral regurgitation (MR) may be seen in patients who are candidate for undergoing isolated aortic valve replacement (AVR), determining the effectiveness of AVR surgery on MR rate improvement can be effective in designing a protocol to deal with patients with functional MR. The purpose of this study was to examine the echocardiographic changes after AVR surgery with a focus on changes in MR. METHODS: The research was conducted as a before-after observational study on patients hospitalized in Baqiyatallah Hospital, Tehran, Iran, who were undergone AVR surgery between 2011 and 2012. After selecting the patients and obtaining informed consent to participate in the project, transthoracic echocardiographic data were collected by a specialist in Cardiology Echocardiography using ViVid 7 device before and till one week after AVR surgery. The MR rate was measured using methods; including Color Flow Doppler, PISA, Vena Cava Width and Effective Regurgitant Orifice. RESULTS: Finally, the study was conducted on 85 patients (mean age = 56.23 ± 6.10 years, 27 women = 31.8%). Of 21 patients with preoperative MR more than mild (moderate, mild to moderate), 20 patients (95%) showed at least one degree decrease in MR. Among 64 patients who had mild MR before the surgery, 29 patients improved (45%), that this difference was statistically significant (P < 0.001). CONCLUSION: The study results showed that in patients with preoperative MR degree higher than mild, after AVR the MR rate improved 24 times more than those who had preoperative MR degree equivalent to mild and lower. However, these changes are not affected by other echocardiographic changes and patients demographic characteristics.
https://arya.mui.ac.ir/article_10463_fc8d40c8811c43a316ff552716e2dd69.pdf
2015-03-14
147
152
Echocardiography
Heart Valve Prosthesis Implantation
Mitral Valve Regurgitation
Arezoo
Khosravi
md.researcher@yahoo.com
1
Assistant Professor, Department of Cardiology, Cardiovascular Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
AUTHOR
Hadi
Sheykhloo
2
Cardiologist, Department of Cardiology, Cardiovascular Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
AUTHOR
Reza
Karbasi-Afshar
3
Assistant Professor, Department of Cardiology, Cardiovascular Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
AUTHOR
Amin
Saburi
aminsaburi@yahoo.com
4
Birjand Atherosclerosis and Coronary Artery Research Center, Birjand University of Medical Sciences, Birjand AND Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
LEAD_AUTHOR
ORIGINAL_ARTICLE
Evaluating the impact of fractional flow reserve-guided percutaneous coronary intervention in intermediate coronary artery lesions on the mode of treatment and their outcomes: An Iranian experience
BACKGROUND: Today, the fractional flow reserve (FFR) guides the physician to select suitable patients with intermediate severity coronary lesions in angiography that should be treated or not with stent. The aim of this study was to evaluate the impact of using FFR in the selection of appropriate treatment strategy in angiographic intermediate coronary lesions and their short-term outcome in a sample of Iranian population. METHODS: In a prospective cohort, 34 patients who had intermediate coronary artery lesion(s), defined as having a 40-70% diameter stenosis, as determined by visual estimation or quantitative coronary angiography were enrolled through a convenience sampling method. All patients underwent FFR measurement to decide whether percutaneous coronary intervention should be performed. The results of visual assessment, quantitative coronary angiography, and functional assessment of the severity of coronary stenosis were compared. Significant stenosis was defined as FFR < 0.80. All patients were followed for 6 months for the incidence of major advanced cardiac events. RESULTS: In this study, 34 patients (22 male and 12 female) with mean age of 57 ± 8 (range 45-70) were included. In 26.47% (9/34) of patients, FFR was < 0.80, they underwent coronary angioplasty. The correlation between visual estimation and quantitative assessment of lesion diameter was 0.804 (P < 0.001). During the follow-up period, no major advanced cardiac events were reported. In addition, 5.88 (2/34) of patients had a left main (LM) lesion with FFR > 0.80 and stenting was done to the other vessels with significant coronary lesions. CONCLUSION: Measurement of FFR is a useful approach in making clinical decisions about revascularization procedures in patients with moderate coronary artery lesion severity, especially in LM and multivessel disease. This study showed that not only FFR can change treatment plan of the patients, but also it would improve clinical outcomes.
https://arya.mui.ac.ir/article_10464_f3b7ac6ce06b44c689e69d85ea641a1c.pdf
2015-07-21
153
159
Fractional Flow Reserve Myocardial
Coronary Stenosis
Coronary Angiography
Alireza
Khosravi
alirezakhosravif@gmail.com
1
Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Mohammad Reza
Pourbehi
mr_purbehi@yahoo.com
2
Assistant Professor, The Persian Gulf Nuclear Medicine Research Center AND Department of Interventional Cardiology, Bushehr University of Medical Sciences, Bushehr, Iran
LEAD_AUTHOR
Masoud
Pourmoghaddas
3
Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Afshin
Ostovar
af_ostovar@yahoo.com
4
Assistant Professor, The Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, Iran
AUTHOR
Mohammad Reza
Akhbari
5
Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Fereshteh
Ziaee-Bideh
6
Assistant Professor, The Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, Iran
AUTHOR
Jafar
Golshahi
7
Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Shahin
Shirani
8
Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
ORIGINAL_ARTICLE
Rare post-operative complications of large mediastinal tumor resection
Background: There are some reports in the literature, which suggest that cardiac tamponade drainage may transiently affect systolic function and also cause acute respiratory distress syndrome (ARDS). We did not find any reports of acute ventricular failure and ARDS secondary to mediastinal tumor resection without tamponade. Case Report: Here we report a 48-year-old woman presenting with massive pericardial effusion without tamponade in whom tumor was resected through median sternotomy using cardiopulmonary bypass. ARDS and acute heart failure were two rare complications that happened at the end of the operation secondary to a sudden decompression of the heart from tumor pressure. Conclusion: ARDS and acute heart failure are two rare complications, which can happen after large mediastinal tumor resection.
https://arya.mui.ac.ir/article_10465_c371ae3bcc6216ccf3dc9ab38e0a2ca0.pdf
2015-03-07
160
162
Heart Failure
Acute Respiratory Distress Syndrome
Mediastinal Neoplasms
Pericardium
Mohsen
Mirmohammadsadeghi
1
Associate Professor, Department of Cardiovascular Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan,
AUTHOR
Amir
Mirmohammadsadeghi
amirmirmohammadsadeghi@gmail.com
2
Assistant Professor, Department of Cardiovascular Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
LEAD_AUTHOR
ORIGINAL_ARTICLE
Long-term pulmonary functional status following coronary artery bypass grafting surgery
BACKGROUND: The present study aimed to describe the long-term alterations of pulmonary function and also to describe its association with post-operative pain after coronary artery bypass grafting (CABG) surgery. METHODS: In this prospective study, thirty non-smoker male patients undergoing isolated on-pump CABG were consecutively included in this study. Pulmonary function measurements were performed, in a sitting position, preoperatively, a week postoperatively, and 6 months after the surgery using a Medical Graphics PF/Dx pulmonary function system. Pain was determined by using visual analog scale (VAS) pain scores with a standardized questionnaire’s. RESULTS: Regarding functional class, all patients had New York Heart Association (NYHA) Class II to III. A week after operation, a severe restrictive pulmonary impairment was revealed with a mean decrease in VC to 60.9 ± 9.2% and in forced expiratory volume in one second (FEV1) to 64.6 ± 12.2% of pre-operative values (P < 0.001). Regarding sternotomy related pain, the mean pain VAS score was preoperatively 3.3 ± 1.5 that reached to 6.2 ± 2.5 and 4.8 ± 2.2 1 week and 6 months after the operation (P < 0.001). The trend of the changes in pain score within 6 months of operation was significantly similar to the trend of the changes in some pulmonary function indices such as FEV% and residual volume (RV). CONCLUSION: A significant reduction is expected in most pulmonary functional parameters following CABG despite normal pulmonary function state preoperatively. Severe pain originated from sternotomy may be an important factor related to pulmonary dysfunction following CABG.
https://arya.mui.ac.ir/article_10466_7eb4b388af74e7c2df43ac5c0388837c.pdf
2015-03-07
163
166
Pulmonary Functional
Coronary Artery Bypass Grafting
Hamid
Rouhi-Boroujeni
1
Clinical Biochemistry Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
AUTHOR
Hojjat
Rouhi-Boroujeni
dr_rohib@yahoo.com
2
Member of Student Research Committee, Medical plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
LEAD_AUTHOR
Parnia
Rouhi-Boroujeni
3
Department of Pharmacology, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran
AUTHOR
Morteza
Sedehi
4
Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
AUTHOR
ORIGINAL_ARTICLE
Journal Index
Click to download the index of this issue.
https://arya.mui.ac.ir/article_10458_8b67f3d93a1a3fafeb20e428b5fff394.pdf
2015-03-01
Index
Journal
arya@crc.mui.ac.ir
1
LEAD_AUTHOR