%0 Journal Article %T The relation between changes in electrocardiography and disease severity in SARS-CoV2 infected patients %J ARYA Atherosclerosis Journal %I Cardiovascular research institute, Isfahan University of Medical Sciences %Z 1735-3955 %A Alimi, Hedieh %A Emadzadeh, Maryam %A Noughab, Seyyed Mahdiyar %D 2022 %\ 06/01/2022 %V 18 %N 6 %P 1-8 %! The relation between changes in electrocardiography and disease severity in SARS-CoV2 infected patients %K COVID-19 %K Pneumonia %K complete heart block %R 10.48305/arya.2022.11845.2521 %X BACKGROUND: Coronavirus disease 2019 (COVID-19) may lead to myocardial damage and arrhythmia.Patients with ECG changes have shown an increased risk of mortality.OBJECTIVE: We aimed to study the changes in the electrocardiogram, which may be of great significancefor risk stratification of COVID-19-positive patients.METHOD: A retrospective study was conducted to compare electrocardiogram changes and diseaseseverity markers in COVID-19-positive patients admitted to a referral hospital between February 20 andMarch 20, 2020.RESULTS: Our study consisted of 201 cases, including 123 males and 78 females. Ages ranged between 16and 97 years old. Fifty-two (25.9%) cases had a history of ICU admission. Multivariate logistic regressionanalysis showed that a low O2 saturation level (OR = 0.920, 95% CI 0.868–0.976, p=0.005), several labtests, ECG changes (OR = 46.84, 95% CI 3.876– 566.287, P = .002) and Age (OR = 1.03, 95% CI 1.000–1.065, P = .048) were the independent risk factors for predicting mortality rate.In addition, we utilized multivariate logistic regression analysis, demonstrating that LBBB (OR = 4.601,95% CI: 1.357–15.600, P=0.014) is the only ECG risk factor associated with morbidity in elderly patientswith ECG changes.CONCLUSIONS: ECG changes are strong indicators of high mortality rates in elderly COVID-19 patients.ECG interpretations should therefore be used for risk stratification and predicting the need for ICU admission. %U https://arya.mui.ac.ir/article_26287_21eb8f2eb46b995ca2768a58cd41766b.pdf