%0 Journal Article %T The Role of Advanced Echocardiographic Parameters of the Left Atrial Function in the Incidence of Cryptogenic Ischemic Stroke: A Review %J ARYA Atherosclerosis Journal %I Cardiovascular research institute, Isfahan University of Medical Sciences %Z 1735-3955 %A Naghnaeian, Mina %A Soleimani, Azam %A Zavar, Reihaneh %A Sadeghi, MD, Masoumeh %D 2023 %\ 02/01/2023 %V 19 %N 2 %P 50-57 %! The Role of Advanced Echocardiographic Parameters of the Left Atrial Function in the Incidence of Cryptogenic Ischemic Stroke: A Review %K cryptogenic strokes %K ischemic strokes %K left atrium %K echocardiographic %K Review %R 10.48305/ARYA.2023.26574.2807 %X Stroke is one of the primary causes of morbidity and mortality worldwide, including a large proportionof cryptogenic strokes. Long-term electrocardiographic monitoring is beneficial in prospective studies fordetecting atrial fibrillation in patients with cryptogenic stroke. This review aimed to evaluate the advancedechocardiographic parameters and their roles in assessing left atrial (LA) function in the incidence ofcryptogenic and ischemic strokes. Main resources, including PubMed, Scopus, and ISI Web of Sciencedatabases, were evaluated for articles published in English from 2010 until May 2021. LA echocardiographicparameters such as LA strain and strain rate, isovolumetric relaxation time (IVRT), the mean left atrialvolume index (LAVI), LA reservoir volume, systole strain rate (SSR) of left atrial appendage, and lack ofLA function response to maximal exercise as measured by the LA ejection fraction during rest and exercisecould be considered for assessing the risk of cryptogenic strokes and ischemic strokes. The results indicatedthat increased LA volumes and reduced LA strain rate were correlated with cryptogenic stroke. Advancedparameters of LA function, measured by speckle tracking echocardiography, such as strain and strainrate values in different parts of the cardiac cycle, in addition to standard measures of LA function suchas LA ejection fraction and LAVI, will define an excellent understanding regarding LA myopathy and riskassessment of cryptogenic stroke, independent of considering conventional cardiovascular risk factors. %U https://arya.mui.ac.ir/article_24326_dcfc0696682b356e8328c0b32dc779fd.pdf