%0 Journal Article %T Association between sleep duration and electrocardiographic ischemic changes in middle-aged population: Isfahan Healthy Heart Program %J ARYA Atherosclerosis Journal %I Cardiovascular research institute, Isfahan University of Medical Sciences %Z 1735-3955 %A Khani, Mahdi %A Najafian, Jamshid %A Taheri, Marzieh %A Akhavan-Tabib, Afshan %A Hosseini, Shidokht %D 2018 %\ 06/25/2018 %V 14 %N 3 %P 115-121 %! Association between sleep duration and electrocardiographic ischemic changes in middle-aged population: Isfahan Healthy Heart Program %K Myocardial Ischemia %K Electrocardiography %K Sleep Deprivation %R 10.22122/arya.v14i3.1656 %X BACKGROUND: Recent studies examining the association between sleep duration and cardiovascular disease (CVD) showed inconsistent results. The aim of our study was to evaluate the association between self-reported night sleep duration and ischemic changes in electrocardiography (ECG).METHODS: We conducted this cross-sectional study on 3513 participants from Iranian middle-aged population as a part of Isfahan Healthy Heart Program (IHHP), Isfahan, Iran. Sleep duration was obtained by questioning participants. The frequency of electrocardiographic ischemic changes was calculated using ECG Minnesota coding system.RESULTS: Short sleep duration was associated with increased frequency of electrocardiographic ischemic changes. In a fully adjusted multiple logistic regression analysis, the odds ratio (OR) for short sleep duration less than 5 hours per night was 1.501 [95% confidence interval (CI) for OR: 1.085-2.076] compared to 8 hours of sleep. After stratifying the study population into sex groups, the association remained significant only in women. The OR for short sleep less than 5 hours per night was 1.565 (95% CI for OR: 1.052-2.329) and 1.455 (95% CI for OR: 0.833-2.539) in women and men, respectively. There was no association between long sleep duration and electrocardiographic ischemic changes in men and women.CONCLUSION: We concluded that there is a positive association between short sleep duration and frequency of electrocardiographic ischemic changes in middle-aged women. This association suggests that short sleep duration may increase the risk of ischemic heart disease (IHD) in women, and this need to be evaluated in further studies. %U https://arya.mui.ac.ir/article_10631_b31ae30639adbe415ae408cf2f8e0692.pdf