@article { author = {Taghdir, Maryam and Djazayeri, Abolghasem and Djalali, Mahmoud and Eshraghian, Mohammadreza and Rajab, Asadollah and Sadrzade Yegane, Haleh and Ashourpour, Mahkameh and Sepandi, Mojtaba}, title = {RELATIONSHIPS OF SERUM LEPTIN CONCENTRATION WITH INSULIN, GLUCOSE, HbA1c LEVELS AND INSULIN RESISTANCE IN OVERWEIGHT POST-MENOPAUSAL DIABETIC WOMEN}, journal = {ARYA Atherosclerosis Journal}, volume = {5}, number = {4}, pages = {-}, year = {2010}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {Abstract    BACKGROUND: Leptin, the product of the ob gene, could have a role in the pathogenesis of obesity and non-insulin dependent diabetes mellitus (NIDDM). The aim of this study was to investigate relationships between serum leptin concentration and insulin, glucose, HbA1c levels and insulin resistance in diabetic women.    METHODS: We studied 45 diabetic women and 45 healthy women (controls) who aged 45-60 years and had BMI of 25-30 kg/m2. Serum leptin, insulin, HbA1c, fasting blood sugar and insulin resistance were determined in the two groups.    RESULTS: There was a significant positive correlation between leptin and insulin (r = 0.295, P = 0.049) and insulin resistance (r = 0.329, P = 0.027) in controls but non-significant correlation between leptin and HbA1c and fasting blood sugar were observed in the two groups.    CONCLUSION: This study did not document any significant relationship between serum leptin and insulin, glucose, HbA1c and insulin resistance in diabetic women.      Keywords: Type 2 Diabetes Mellitus, Leptin, Insulin.}, keywords = {}, url = {https://arya.mui.ac.ir/article_10023.html}, eprint = {https://arya.mui.ac.ir/article_10023_8bd63da526b884d4518ce85f6054065d.pdf} }