@article { author = {Behjati, Mohaddeseh}, title = {Orthopedic problems: An underestimated hidden risk factor for development and progression of atherosclerosis; An inconspicuous joint link}, journal = {ARYA Atherosclerosis Journal}, volume = {12}, number = {3}, pages = {115-117}, year = {2016}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {-}, keywords = {}, url = {https://arya.mui.ac.ir/article_10524.html}, eprint = {https://arya.mui.ac.ir/article_10524_e1314a640c7f8dde8969aa72bc6516e2.pdf} } @article { author = {Zarei, Mahnaz and Farahnak, Zahra and Hosseinzadeh-Attar, Mohammad Javad and Javanbakht, Mohammad Hassan and Hosseinzadeh, Payam and Derakhshanian, Hoda and Farahbakhsh-Farsi, Payam and Djalali, Mahmoud}, title = {Lipid peroxidation and antioxidant enzymes activity in controlled and uncontrolled Type 2 diabetic patients}, journal = {ARYA Atherosclerosis Journal}, volume = {12}, number = {3}, pages = {118-123}, year = {2016}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: This study was designed to compare lipid peroxidation and antioxidant enzymes activity in Type 2 diabetes patients with good or weak glycemic control. METHODS: In this case-control study, 62 Type 2 diabetic patients with glycated hemoglobin (HbA1c) between 6 and 8 were enrolled as the controlled group and 55 patients with HbA1c > 8 were selected as an uncontrolled group. Patients were all referred to Iranian Diabetes Association in Tehran, Iran, from 2010 onward. Groups were chosen by convenience sampling and were matched based on age, sex and duration of disease. Demographic questionnaire, two 24-hour food recall, HbA1c, insulin, malondialdehyde (MDA), superoxide dismutase (SOD), and catalase were measured in blood samples. Data were analyzed by Food Processor II and SPSS software. RESULTS: A mean daily consumption of energy, carbohydrate, protein, and fat was not significantly different between two groups. MDA in the uncontrolled group was significantly higher than controlled group (2.03 ± 0.88 vs. 1.65 ± 1.01 nmol/ml; P = 0.030). A mean SOD was slightly higher in the uncontrolled group comparing to the control group (843.3 ± 101.9 vs. 828.0 ± 127.3 U/g Hb; P = 0.400). CONCLUSION: These data suggest that MDA as a lipid peroxidation indicator is higher in uncontrolled diabetes probably due to chronic high blood sugar followed by higher oxidative stress.   }, keywords = {Antioxidant,Lipid Peroxidation,Diabetes Mellitus}, url = {https://arya.mui.ac.ir/article_10525.html}, eprint = {https://arya.mui.ac.ir/article_10525_aafb6c6c3ce200e7f8c9971d2d7d8ed7.pdf} } @article { author = {Yazdani-Bakhsh, Razieh and Javanbakht, Mehdi and Sadeghi, Masoumeh and Mashayekhi, Atefeh and Ghaderi, Hossein and Rabiei, Katayoun}, title = {Comparison of health-related quality of life after percutaneous coronary intervention and coronary artery bypass surgery}, journal = {ARYA Atherosclerosis Journal}, volume = {12}, number = {3}, pages = {124-131}, year = {2016}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Health-related quality of life (HRQOL) evaluation is an important measure of the impact of the disease. As more people with coronary heart disease (CHD) live longer, doctors and researchers want to know how they manage in day to day life. It looked like adults with CHD had a decrease QOL. The aim of this study was to comparison of HRQOL of patients who underwent percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) and to assess its main determinants in the whole sample of coronary artery disease (CAD) patients. METHODS: The study was carried out to estimate HRQOL of 109 patients who underwent invasive coronary revascularization [PCI (n = 75) and CABG (n = 34)]. We applied HRQOL after 6 months and 2 years in both groups and scores were compared. The HRQOL data were obtained using MacNew Heart Disease questionnaire with dimensions emotional, physical and social that estimated. Data entry and analysis were performed by SPSS. RESULTS: A total MacNew scale in CABG and PCI group in 6 months after treatment were 45.32 ± 13.75 and 53.52 ± 15.63, respectively (P = 0.010). After 2 years HRQOL mean changed to 51.176 ± 14.80 and 49.55 ± 16.22, respectively, in CABG and PCI group (P = 0.428). Our results in within-group analysis showed total MacNew scale and its subscales were changed significantly after 2 years in CABG and PCI group’s scores were detected. We found in the whole sample of CAD patients those who had a higher level of income and education and were not either overweight or obese experienced better HRQOL. CONCLUSION: Our results showed that patients who underwent PCI experienced significantly higher HRQOL in 6 months after revascularization but over 24 months follow-up no difference was observed between the two groups.   }, keywords = {Quality of Life,Percutaneous Coronary Intervention,Coronary Artery Bypass Graft,MacNew scale,Iran}, url = {https://arya.mui.ac.ir/article_10526.html}, eprint = {https://arya.mui.ac.ir/article_10526_01b09727a9f18f82d7a03c61cc86e0e4.pdf} } @article { author = {Kazemi-Saleh, Davoud and Koosha, Pooya and Sadeghi, Masoumeh and Sarrafzadegan, Nizal and Karbasi-Afshar, Reza and Boshtam, Mansoureh and Oveis-Gharan, Shahram}, title = {Predictive role of adiponectin and high-sensitivity C-reactive protein for prediction of cardiovascular event in an Iranian cohort study: The Isfahan Cohort Study}, journal = {ARYA Atherosclerosis Journal}, volume = {12}, number = {3}, pages = {132-137}, year = {2016}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Numerous studies have been conducted on the predictive effects of high-sensitivity C-reactive protein (hs-CRP) on cardiovascular events. Few studies have been conducted to investigate the effects of adiponectin for the prediction of the incident of cardiovascular events in the Middle East area. This study compared the predictive effect of hs-CRP and adiponectin on healthy volunteers for the prediction of cerebrovascular disease (CVD). METHODS: This nested case-control in original Isfahan Cohort Study (ICS) was conducted from 2001 to 2011. Participants were selected from ICS. The case group included participants with CVD while the control group included participants without CVD. The level of hs-CRP and adiponectin was measured in the blood samples collected in the year 2007. Thereafter, the statistical analyses were performed to determine the predictive value of hs-CRP and adiponectin in CVD prediction. RESULTS: The results showed that before the elimination of diabetes effect; there was a significant difference between the two groups, in terms of the mean of adiponectin (P = 0.019) and no significant difference was observed in hs-CRP levels (P = 0.673). However, after eliminating the factor of diabetes, there was no significant difference between the case and control groups in adiponectin and hs-CRP levels (P = 0.184, P = 0.946). The results showed that the odds ratio (OR) of the adiponectin level was 0.879 [95% confidence interval (CI): 0.719-1.075, P = 0.210] while the OR of hs-CRP was 1.045 (95% CI: 0.922-1.185, P = 0.491). Furthermore, it was shown that after adjustment for age, sex, and diabetes; the OR of adiponectine was 0.875 (95% CI: 0.701-1.091, P = 0.235) and that of hs-CRP was 1.068 (95% CI: 0.935-1.219, P = 0.333). CONCLUSION: The results show that adiponectin and hs-CRP cannot be predictors for cardiovascular events in a healthy population. Risk factors such as diabetes limit the use of adiponectin as a CVD predictor. }, keywords = {Adiponectin,High-Sensitivity C-Reactive Protein,Cardiovascular Disease}, url = {https://arya.mui.ac.ir/article_10527.html}, eprint = {https://arya.mui.ac.ir/article_10527_6913ed0654f96c19e54fa6edc3ef9e64.pdf} } @article { author = {Komasi, Saeid and Saeidi, Mozhgan}, title = {What is role of sex and age differences in marital conflict and stress of patients under Cardiac Rehabilitation Program?}, journal = {ARYA Atherosclerosis Journal}, volume = {12}, number = {3}, pages = {138-145}, year = {2016}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: To investigate the role of sex and age differences in marital conflict and stress of patients who were under cardiac rehabilitation (CR) program. METHODS: The data of this cross-sectional study were collected from the database of the CR Department of Imam Ali Hospital, Kermanshah, Iran. The demographics and medical data of 683 persons were collected from January 2003 and January 2010 using medical records, the Beck Anxiety Inventory, the Beck Depression Inventory, the Hudson’s Index of Marital Stress, and the Structured Clinical Interview for axis I disorders. Data were analyzed through Analysis of Covariance and Bonferroni test. RESULTS: About 74.8% of the subjects were male. After adjustment for age, educational level, anxiety, and depression-the findings showed that women in CR program had a higher level of marital stress compared to men (54.75 ± 2.52 vs. 49.30 ± 0.89; P = 0.042). Furthermore, it was revealed that women who aged 56-65 years and more experienced higher level of marital stress compared to younger patients (P < 0.050); however, no significant difference was observed between different age groups in male patients (P > 0.050). CONCLUSION: Marital conflict and stress threaten healthiness of women who aged 56-65 years more prominently than does in males or younger patients. Regarding the effect of marital stress on recurrence of the disease and cardiac-related morbidity and mortality in women, providing effective education and interventions to this group of patients, especially older women and even their spouses could be one of the useful objectives of CR programs. }, keywords = {Marital Conflict,Psychologic Stress,Sex Differences,Rehabilitation,Cardiac Disease}, url = {https://arya.mui.ac.ir/article_10528.html}, eprint = {https://arya.mui.ac.ir/article_10528_9f70804be06d95a274b0a46f770e8762.pdf} } @article { author = {Karimi-Alavijeh, Farzaneh and Jalili, Saeed and Sadeghi, Masoumeh}, title = {Predicting metabolic syndrome using decision tree and support vector machine methods}, journal = {ARYA Atherosclerosis Journal}, volume = {12}, number = {3}, pages = {146-152}, year = {2016}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Metabolic syndrome which underlies the increased prevalence of cardiovascular disease and Type 2 diabetes is considered as a group of metabolic abnormalities including central obesity, hypertriglyceridemia, glucose intolerance, hypertension, and dyslipidemia. Recently, artificial intelligence based health-care systems are highly regarded because of its success in diagnosis, prediction, and choice of treatment. This study employs machine learning technics for predict the metabolic syndrome. METHODS: This study aims to employ decision tree and support vector machine (SVM) to predict the 7-year incidence of metabolic syndrome. This research is a practical one in which data from 2107 participants of Isfahan Cohort Study has been utilized. The subjects without metabolic syndrome according to the ATPIII criteria were selected. The features that have been used in this data set include: gender, age, weight, body mass index, waist circumference, waist-to-hip ratio, hip circumference, physical activity, smoking, hypertension, antihypertensive medication use, systolic blood pressure (BP), diastolic BP, fasting blood sugar, 2-hour blood glucose, triglycerides (TGs), total cholesterol, low-density lipoprotein, high density lipoprotein-cholesterol, mean corpuscular volume, and mean corpuscular hemoglobin. Metabolic syndrome was diagnosed based on ATPIII criteria and two methods of decision tree and SVM were selected to predict the metabolic syndrome. The criteria of sensitivity, specificity and accuracy were used for validation. RESULTS: SVM and decision tree methods were examined according to the criteria of sensitivity, specificity and accuracy. Sensitivity, specificity and accuracy were 0.774 (0.758), 0.74 (0.72) and 0.757 (0.739) in SVM (decision tree) method. CONCLUSION: The results show that SVM method sensitivity, specificity and accuracy is more efficient than decision tree. The results of decision tree method show that the TG is the most important feature in predicting metabolic syndrome. According to this study, in cases where only the final result of the decision is regarded significant, SVM method can be used with acceptable accuracy in decision making medical issues. This method has not been implemented in the previous research. }, keywords = {Machine Learning,Metabolic Syndrome,Decision Tree,Support Vector Machine}, url = {https://arya.mui.ac.ir/article_10529.html}, eprint = {https://arya.mui.ac.ir/article_10529_3ab86bbd7ad01c21bec54c0d025f7e3d.pdf} } @article { author = {Vasheghani-Farahani, Ali and Tajdini, Masih and Mohsenizadeh, Seyed Abolfazl and Hosseini, Seyed Mohammad Reza}, title = {Reversible left bundle branch block should be mentioned in cardiac resynchronization therapy; A clinical case report}, journal = {ARYA Atherosclerosis Journal}, volume = {12}, number = {3}, pages = {153-155}, year = {2016}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Cardiac resynchronization therapy (CRT) is a medical device to help cardiac synchronized contractility by electrical impulses. Improvement of symptoms and left ventricular systolic function, reducing hospital admissions and mortality in patients with moderate to severe heart failure are the main benefits of administration of cardiac resynchronization therapy. CASE REPORT: In this article, we describe a case of heart failure and left bundle branch block (LBBB) who was candidate for cardiac resynchronization therapy; but after managing hyperkalemia, left bundle branch block resolved, ejection fraction increased and cardiac resynchronization therapy implantation was canceled. CONCLUSION: Exclusion of treatable causes is the first important step before any interventions. Now there is an important question; is cardiac resynchronization therapy effective in patients with heart failure and transient or intermittent left bundle branch block? }, keywords = {Reversible Left Bundle Branch Block,Cardiac Resynchronization Therapy,Hyperkalemia}, url = {https://arya.mui.ac.ir/article_10530.html}, eprint = {https://arya.mui.ac.ir/article_10530_447be199fe9d6bb15c6fdd46859f078d.pdf} } @article { author = {Mansouritorghabeh, Hassan}, title = {Normal range of bleeding time in west of Iran}, journal = {ARYA Atherosclerosis Journal}, volume = {12}, number = {3}, pages = {156-157}, year = {2016}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {-}, keywords = {}, url = {https://arya.mui.ac.ir/article_10531.html}, eprint = {https://arya.mui.ac.ir/article_10531_81ae9a7f6d17ecf4440e823c98d5e6a2.pdf} } @article { author = {Journal, Index}, title = {Journal Index}, journal = {ARYA Atherosclerosis Journal}, volume = {12}, number = {3}, pages = {-}, year = {2016}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {Click to download the index of this issue.}, keywords = {}, url = {https://arya.mui.ac.ir/article_10523.html}, eprint = {https://arya.mui.ac.ir/article_10523_2aff49d3424336033329e7d60f5fbeb3.pdf} }