@article { author = {Pourmoghaddas, Ali and Moghaddasian, Adrineh and Garakyaraghi, Mohammad and Nezarat, Negin and Mehrabi, Ali}, title = {Heart rate recovery in exercise test in diabetic patients with and without microalbuminuria}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {167-171}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Diabetes mellitus (DM) has a lot of complications such as macrovessel and microvessel disease. Another complication of DM is cardiac autonomic neuropathy (CAN), which have effect on automatic nervous system of heart. Failure in heart rate slowing after exercise is a presentation of this abnormality.METHODS: We selected diabetic patients and divided them to case and control group based on microalbuminuria. Case group comprised of diabetic patients with microalbuminuria and control group included those without microalbuminuria. Patients in both groups exercised on treadmill using Bruce protocol and heart rate was measured in first and second minutes in the recovery period. RESULTS: We selected 35 patients with microalbuminuria (case group) and 35 without microalbuminuria (control group) among diabetic patients. No statistically significant difference was seen in sex and age between case and control groups. Heart rate recovery in the first minute of recovery in the case and control groups did not show significant difference; but in the second minute of recovery, it was significantly higher in control group (97 ± 19.4 vs. 101.9 ± 12.4 beat per minute, P = 0.04). CONCLUSION: In this study we evaluated the heart rate recovery or deceleration in diabetic patients with albuminuria and without microalbuminuria in recovery phase after exercise test. We found out that heart rate recovery at the second minute in the case and control groups has statistically significant difference but at the first minute, it did not.   Keywords: Diabetes Mellitus, Exercise Test, Heart Rate Recovery}, keywords = {}, url = {https://arya.mui.ac.ir/article_10348.html}, eprint = {https://arya.mui.ac.ir/article_10348_0ec18e8c0c436fc2c3fbade6a12c979d.pdf} } @article { author = {Asemi, Zatollah and Jazayeri, Shima and Najafi, Mohammad and Samimi, Mansooreh and Shidfar, Farzad and Tabassi, Zohreh and Shahaboddin, MohamadEsmaeil and Esmaillzadeh, Ahmad}, title = {Association between markers of systemic inflammation, oxidative stress, lipid profiles, and insulin resistance in pregnant women}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {172-178}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Increased levels of pro-inflammatory factors, markers of oxidative stress and lipid profiles are known to be associated with several complications. The aim of this study was to determine the association of markers of systemic inflammation, oxidative stress and lipid profiles with insulin resistance in pregnant women in Kashan, Iran. METHODS: In a cross-sectional study, serum high sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-α), fasting plasma glucose (FPG), serum insulin, 8-oxo-7, 8-dihydroguanine (8-oxo-G), total cholesterol, triglyceride, HDL-cholesterol, and plasma total antioxidant capacity (TAC) were measured among 89 primigravida singleton pregnant women aged 18-30 years at 24-28 weeks of gestation. Pearson’s correlation and multiple linear regressions were used to assess their relationships with homeostatic model assessment of insulin resistance (HOMA-IR). RESULTS: We found that among biochemical indicators of pregnant women, serum hs-CRP and total cholesterol levels were positively correlated with HOMA-IR (β = 0.05, P = 0.006 for hs-CRP and β = 0.006, P = 0.006 for total cholesterol). These associations remained significant even after mutual effect of other biochemical indicators were controlled (β = 0.04, P = 0.01 for hs-CRP and β = 0.007, P = 0.02 for total cholesterol). Further adjustment for body mass index made the association of hs-CRP and HOMA-IR disappeared; however, the relationship for total cholesterol remained statistically significant. CONCLUSION: Our findings showed that serum total cholesterol is independently correlated with HOMA-IR score. Further studies are needed to confirm our findings. Keywords: Inflammation, Oxidative Stress, Insulin Resistance, Pregnancy}, keywords = {}, url = {https://arya.mui.ac.ir/article_10349.html}, eprint = {https://arya.mui.ac.ir/article_10349_30bd0de104f068437f1e9e6efbb5d463.pdf} } @article { author = {Saeidi, Marzieh and Mostafavi, Samaneh and Heidari, Hosein and Masoudi, Sepehr}, title = {Effects of a comprehensive cardiac rehabilitation program on quality of life in patients with coronary artery disease}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {179-185}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Health-related quality of life is an important factor to evaluate effects of different interventions in cardiovascular diseases. Improvement in quality of life (QOL) is an important goal for individuals participating in cardiac rehabilitation (CR) programs. The purpose of this study was to assess the impact of comprehensive CR on QOL in patients with cardiovascular disease (CAD). METHODS: In this quasi-experimental before-after study, the files of 100 patients with CAD who were referred to rehabilitation department of Isfahan Cardiovascular Research Institute were studied using a consecutive sampling method. Data collection was performed from the patient's files including their demographics, ejection fraction, functional capacity, and resting heart rate. All patients participated in a comprehensive CR program and completed the validated questionnaire Short-Form 36 Health Status Survey (SF-36), before and after CR program. Data was analyzed based on sex and age groups (≥ 65 and < 65 years) using independent t-test and paired t-test (to compare variables between groups and before and after CR, respectively). RESULTS: After CR, scores of all physical domains of the SF-36 including physical function (PF), physical limitation (PL), body pain (BP) and vitality (V) in addition to general health (GH) were significantly improved in all patients (P < 0.05) compared to the baseline. Patients with age < 65 years had greater improvements in mental health (MH) and social function (SF) than patients with age ≥ 65 years (P < 0.05). Women had greater improvement in PF, V and MH compared to men (P < 0.05). CONCLUSION: These results indicated that CR can improve QOL in cardiac patients especially in women. Elderly patients get benefit the same as other patients in physical domains. Keywords: Quality of Life, Cardiac Rehabilitation, Cardiovascular Diseases}, keywords = {}, url = {https://arya.mui.ac.ir/article_10350.html}, eprint = {https://arya.mui.ac.ir/article_10350_36a6f5d6822faea8d312df7d8509de53.pdf} } @article { author = {Molazem, Zahra and Rezaei, Soheila and Mohebbi, Zinat and Ostovan, Mohammad-Ali and Keshavarzi, Sareh}, title = {Effect of continuous care model on lifestyle of patients with myocardial infarction}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {186-191}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Myocardial infarction (MI) is a life threatening disease that influences the physical, psychological and social dimensions of the individual. Improper lifestyle is one of the causes of this disease. The use of nursing models could be one of the important and fundamental steps in changing the risk factors associated with MI. This study was carried out to evaluate the effect of continuous care model on the lifestyle of patients with MI. METHODS: This randomized clinical trial was carried out on 70 patients with MI in coronary care units of hospitals affiliated to Shiraz University of Medical Sciences. Enrolled patients were randomly assigned to intervention or control groups using a randomization list (random permutated blocks with length 4). The continuous care model was used for 35 patients in the intervention group for a period of 3 months and in the control group, the usual cares were applied for 35 patients. Data were collected through lifestyle questionnaire before the intervention and 3 months after. The data were analyzed using chi-square, independent t-test and paired t-test. RESULTS: Patients in the intervention group showed significant improvements in lifestyle (125.6 ± 15.4 vs. 180.1 ± 19.9). Moreover, the lifestyle score of intervention group was significantly better than that of the control group (117.9 ± 22.0 vs. 180.1 ± 19.9; P < 0.001) after three months. CONCLUSION: Applying a continuous care model had positive effects on the lifestyle of patients with Myocardial Infarction. In order to reduce the risk factors and improve the lifestyle of patients with MI, nurses could use this model to create an effective change.   Keywords: Myocardial Infarction, Lifestyle, Continuous Care Model }, keywords = {}, url = {https://arya.mui.ac.ir/article_10351.html}, eprint = {https://arya.mui.ac.ir/article_10351_3a926de5e20bd27e62a8f751d994d8fe.pdf} } @article { author = {Kiani, Amjad and Mirmohammad Sadeghi, Mohsen and Gharipour, Mojgan and Farahmand, Niloofar and Hoveida, Laleh}, title = {Preconditioning by isoflurane as a volatile anesthetic in elective coronary artery bypass surgery}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {192-197}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Some pharmacological preconditioning approaches are utilized as an effective adjunct to myocardial protection, particularly following cardiac procedures. The current study addressed the potential clinical implications and protective effects of isoflurane as an anesthetic most applicable on postoperative myocardial function measured by cardiac biomarkers. METHODS: 46 patients were included in the study. In 23 of them, preconditioning was elicited after the onset of cardiopulmonary bypass via a 5-minute exposure to isoflurane (2.5 minimum alveolar concentration), followed by a 10-minute washout before aortic cross clamping and cardioplegic arrest. 23 case-matched control patients underwent an equivalent period (15 minutes) of pre-arrest isoflurane-free bypass. Outcome measurements included creatine phosphokinase (CPK) and creatine kinase–MB (CK-MB) levels until 24 hours after the surgery. RESULTS: None of the differences in enzyme levels at baseline and 24 hours after surgery between the two groups reached the threshold of statistical significance. The level of CPK was significantly reduced 24 hours after surgery compared with the baseline in the two groups. However, the postoperative release of CPK was consistently smaller in the isoflurane-preconditioned group than in the control group. The release of CK-MB displayed a statistically similar pattern. Multivariate linear regression analysis showed the effect of isoflurane regimen on reducing CPK level within the 24 hours after surgery compared with placebo. CONCLUSION: Our study supports the cardio protective effect of isoflurane and the role of pharmacological preconditioning of the human heart by this volatile anesthetic during elective coronary artery bypass surgery.   Keywords: Preconditioning, Isoflurane, Volatile Anesthetic, Coronary Artery Bypass Surgery }, keywords = {}, url = {https://arya.mui.ac.ir/article_10352.html}, eprint = {https://arya.mui.ac.ir/article_10352_eeab5fe58ce392617340b30320c99505.pdf} } @article { author = {Roohafza, Hamidreza and Khani, Azam and Afshar, Hamid and Garakyaraghi, Mohammad and Amirpour, Afshin and Ghodsi, Basir}, title = {Lipid profile in antipsychotic drug users: A comparative study}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {198-202}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Schizophrenic patients who receive antipsychotic drugs may be highly prone to metabolic disorders such as weight gain, dyslipidemia, and insulin resistance. The objective of the present study was to compare the effect of atypical and conventional antipsychotics on lipid profile. METHODS: 128 schizophrenic patients were enrolled into the study. Patients were divided into two groups. One group had received one type of atypical antipsychotic drug, and, the other, one type of conventional antipsychotic drug. They were considered as atypical and conventional groups. Moreover, both groups had not used any other antipsychotic drugs during the past year. Demographic data and food frequency questionnaire were completed by the participants. Serum triglyceride, total cholesterol (TC), high-density lipoprotein and low-density lipoprotein (LDL) cholesterols, and apolipoprotein A and B (Apo B) were tested by blood sample drawing after 12 hours of fasting through the antecubital vein. Student’s t-test was used to compare atypical and conventional groups. RESULTS: There was no significant difference in age, gender, duration of illness, period of drug consumption, and age at onset of illness in the two groups. Patients in the atypical group used clozapine and risperidone (46.9%) more than olanzapine. In the conventional group 81.3% of patients used phenothiazines. Comparison between lipid profile in the conventional and atypical groups showed a significantly higher mean in TC (P = 0.01), LDL (P = 0.03), and Apo B (P = 0.01) in conventional group than the atypical group. CONCLUSION: In schizophrenic patients, the level of lipid profile had been increased in both atypical and conventional antipsychotic users, especially conventional users, so the effect of antipsychotic drugs should be investigated periodically.   Keywords: Atypical Antipsychotic, Conventional Antipsychotic, Lipid Profile}, keywords = {}, url = {https://arya.mui.ac.ir/article_10353.html}, eprint = {https://arya.mui.ac.ir/article_10353_756fb6bca387583b28e2b8452d01935e.pdf} } @article { author = {Karbasi-Afshar, Reza and Saburi, Amin and Taheri, Saeed}, title = {Clinical associations between renal dysfunction and vascular events: A literature review}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {203-209}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {Chronic kidney disease affects several other organs of the human body, and causes high levels of morbidity and mortality due to these effects. The cardiovascular system is probably the most vulnerable organ to a decrease in kidney function, and responds very fast to this effect. To the extent that, more kidney disease patients die of cardiovascular events than that of the original renal disease. Moreover, cerebrovascular events have been confirmed to increase, and to have inferior outcomes on the general population. In this review article, we aim to review studies investigating effects of renal disease on vascular events. Keywords: Renal Disease, Cardiovascular Disorders, Dialysis, Myocardial Infarction, Risk Factor}, keywords = {}, url = {https://arya.mui.ac.ir/article_10354.html}, eprint = {https://arya.mui.ac.ir/article_10354_54c49947781883f2d9139e13d496fca0.pdf} } @article { author = {Yılmaz, Seyhan and KOÇ, Ayşegül}, title = {Traumatic right pericardial laceration with tension pneumopericardium associated with hemodynamic instability: A case report}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {210-212}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Pneumopericardium is a rare complication following thoracic trauma, and urgent treatment is rendered necessary when it causes tension pneumopericardium due to cardiac tamponade. CASE REPORT: The case presented here is a right pericardial laceration with tension pneumopericardium due to falling from a height, presenting to the emergency clinic of our hospital with hemodynamic instability. CONCLUSION: Pneumopericardium that might develop due to blunt thoracic trauma can easily be diagnosed, may result in cardiac tamponade, and is a potentially fatal pathology without treatment. Keywords: Pneumopericardium, Trauma, Cardiac Tamponade, Fall}, keywords = {}, url = {https://arya.mui.ac.ir/article_10355.html}, eprint = {https://arya.mui.ac.ir/article_10355_1e6a97c3d063d4803668dca763871848.pdf} } @article { author = {Mirmohammadsadeghi, Mohsen and Kiani, Yalda and Nasr, Ali and Zavvar, Reihaneh and Behjati, Mohaddeseh and Rabbani, Majid and Majidi, Elham and Mirmohammadsadeghi, Poya}, title = {Five chambered heart or large atrial appendage aneurysm: A report of two cases}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {213-215}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {BACKGROUND: Isolated intrapericardial LAA aneurysm is a rare cardiac anomaly which manifests with angina, dyspnea on exertion (DOE), systemic embolization, arrhythmia, and congestive heart failure. CASE REPORT: A 30-year-old female and a 46-year-old male were referred for evaluation of abnormal cardiac contour on chest radiograph and echocardiographic findings and non-specific symptoms. Transesophageal echocardiography suggested left atrial appendage (LAA) mass filled with clots. The mass had no compression on cardiac chambers and global ejection fraction was within normal limits. The intraoperative diagnosis was isolated congenital LAA aneurysm. After confirmation of the diagnosis, it was resected. She was discharged with uneventful postoperative course. At follow-up she was asymptomatic. CONCLUSION: These cases demonstrate the role of on-time surgical approaches in the prevention of fatal complication of this rare cardiac anomaly. Keywords: Left Atrial Appendage, Aneurysm, Clot}, keywords = {}, url = {https://arya.mui.ac.ir/article_10356.html}, eprint = {https://arya.mui.ac.ir/article_10356_829596548fffb6eb1569c79a0ebdebf4.pdf} } @article { author = {Journal, Index}, title = {Journal Index}, journal = {ARYA Atherosclerosis Journal}, volume = {9}, number = {3}, pages = {-}, year = {2013}, publisher = {Cardiovascular research institute, Isfahan University of Medical Sciences}, issn = {1735-3955}, eissn = {2251-6638}, doi = {}, abstract = {Click to download the index of this issue}, keywords = {}, url = {https://arya.mui.ac.ir/article_10347.html}, eprint = {https://arya.mui.ac.ir/article_10347_c2e977d148c23dfbbdb3e2a36baa27cd.pdf} }