The Relationship between serum vitamin D levels and ankle-brachial index in patients with metabolic syndrome

Davoud Kazemisaleh, Keivan Kiani, Masoumeh Sadeghi, Hamidreza Roohafza, Minoo Dianatkhah, Nizal Sarrafzadegan


BACKGROUND: Vitamin D deficiency is a prevalent condition in Iran and previous studies have shown that a low level of serum vitamin D is related to low ankle-brachial index (ABI). In the present study, the relationship of the serum level of vitamin D with ABI, as an index for atherosclerosis of peripheral arteries, was evaluated.

METHODS: In this cross-sectional study, data on 91 patients with metabolic syndrome (Mets) from the Isfahan Cohort Study (ICS) were analyzed in order to evaluate the association between serum 25(OH) vitamin D level and ABI. The participants were divided into two groups; group A with desirable serum vitamin D level and group B with abnormal serum vitamin D level. ABI was measured and compared between these groups.

RESULTS: A crude and adjusted model showed no association between vitamin D level and ABI in patients with MetS.

CONCLUSION: It can be concluded that serum vitamin D level could not affect ABI in patients with MetS.


Vitamin D; Ankle Brachial Index; Metabolic Syndrome

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