Document Type : Original Article(s)

Authors

1 Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

2 Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

3 Heart Failure Research Center, Cardiovascular Research Institute AND Department of Epidemiology and Biostatic, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran

4 Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

5 Hypertension Research Center AND Cardiac Intervention Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

6 Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

7 Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences ,Isfahan, Iran

8 Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

9 School of Advanced Technologies in Medicine, ShahidBeheshti University of Medical Sciences, Tehran, Iran

Abstract

BACKGROUND: Our aim was to create and establish a database called “Persian Registry Of cardioVascular diseasE (PROVE)” in order to be used for future research and in addition, as a tool to develop national guidelines for diagnosis, treatment, and prevention of cardiovascular disease (CVD). In this paper, the design and methodology of the PROVE pilot study will be discussed, launched in Isfahan, Iran, in 2015-2016. METHODS: Through establishing PROVE, patients' data were collected from hospitals and outpatient clinics prospectively or retrospectively and followed up for a maximum of three years based on the type of CVDs. The inclusion criteria were as patients with acute coronary syndrome (ACS), ST elevation myocardial infarction (STEMI), stroke, atrial fibrillation (AF), heart failure (HF), congenital heart disease (CHD), percutaneous coronary intervention (PCI), and chronic ischemic cardiovascular disease (CICD). Specific protocols, questionnaires, and glossaries were developed for each registry. In order to ensure the validation of the protocols, questionnaires, data collection, management, and analysis, a well-established quality control (QC) protocol was developed and implemented. Data confidentiality was considered. RESULTS: In order to register patients with ACS, STEMI, stroke, HF, PCI, and CICD, the hospital recorded data were used, whereas, in case of AF and CHD registries, the data were collected from hospitals and outpatient clinics. During the pilot phase of the study in Isfahan, from March 2015 to September 2016, 9427 patients were registered as ACS including 809 as STEMI, 1195 patients with HF, 363 with AF, 761 with stroke, 1136 with CHD, 1200 with PCI, and 9 with CICD. Data collection and management were performed under the supervision of the QC group. CONCLUSION: PROVE was developed and implemented in Isfahan as a pilot study, in order to be implemented at national level in future. It provides a valuable source of valid data that could be used for future research, re-evaluation of current CVD management and more specifically, gap analysis and as a tool for assessment of the type of CVDs, prevention, treatment, and control by health care decision makers.   

Keywords

  1. Amiri Z, Farazmand A, Tolooei MH. Causes of hospitalization of elderly people in hospitals in Rasht in 2000. J Guilan Univ Med Sci 2002; 11(42): 28-32. [In Persian].
  2. Hatami H, Razavi SM, Eftekhar Ardebili H, Majlesi F, Syednozady M, Parizadeh MG. Book comprehensive public health. Tehran, Iran: Arjmand Publications; 2004. p. 1524. [In Persian].
  3. Akbari M. According ten years of the Islamic Republic of Iran on the international goals on Population and Development. Tehran, Iran: Ministry of Health and Medical Education; 2004. p. 14-21. [In Persian].
  4. Kathleen Mahan L, Escott-Stump S. Krause's food & nutrition therapy. Philadelphia, PA: Saunders/Elsevier; 2008. p. 1021.
  5. Sarraf-Zadegan N, Sayed-Tabatabaei FA, Bashardoost N, Maleki A, Totonchi M, Habibi HR, et al. The prevalence of coronary artery disease in an urban population in Isfahan, Iran. Acta Cardiol 1999; 54(5): 257-63.
  6. Sarraf-Zadegan N, Boshtam M, Rafiei M. Risk factors for coronary artery disease in Isfahan, Iran. Eur J Public Health 1999; 9(1): 20-6.
  7. Esteghamati A, Abbasi M, Alikhani S, Gouya MM, Delavari A, Shishehbor MH, et al. Prevalence, awareness, treatment, and risk factors associated with hypertension in the Iranian population: The national survey of risk factors for noncommunicable diseases of Iran. Am J Hypertens 2008; 21(6): 620-6.
  8. SarrafZadegan N, AminiNik S. Blood pressure pattern in urban and rural areas in Isfahan, Iran. J Hum Hypertens 1997; 11(7): 425-8.
  9. Roohafza H, Sadeghi M, Shirani S, Bahonar A, Mackie M, Sarafzadegan N. Association of socioeconomic status and life-style factors with coping strategies in Isfahan Healthy Heart Program, Iran. Croat Med J 2009; 50(4): 380-6.
  10. SarrafZadegan N, Kelishadi R, Baghaei A, Hussein SG, Malekafzali H, Mohammadifard N, et al. Metabolic syndrome: An emerging public health problem in Iranian women: Isfahan Healthy Heart Program. Int J Cardiol 2008; 131(1): 90-6.
  11. Kelishadi R, Sadri G, Tavasoli AA, Kahbazi M, Roohafza HR, Sadeghi M, et al. Cumulative prevalence of risk factors for atherosclerotic cardiovascular diseases in Iranian adolescents: IHHP-HHPC. J Pediatr (Rio J) 2005; 81(6): 447-53.
  12. Fars News Agency. Heart diseases are responsible for 38 percent of deaths in Iran [Online]. [cited 2006]. Available from: URL: from: http://www.farsnews.net/newstext.php?nn=8507010512
  13. SarrafZadegan N, Talaei M, Sadeghi M, Kelishadi R, Oveisgharan S, Mohammadifard N, et al. The Isfahan cohort study: Rationale, methods and main findings. J Hum Hypertens 2011; 25(9): 545-53.
  14. Talaei M, SarrafZadegan N, Sadeghi M, Oveisgharan S, Marshall T, Thomas GN, et al. Incidence of cardiovascular diseases in an Iranian population: The Isfahan Cohort Study. Arch Iran Med 2013; 16(3): 138-44.
  15. Design & Implementing of health information system: Ministry of health and medical education-deputy of research & technology [Online]. [cited 2005]. Available from: URL: http://www.allhealth.org/publications/health_information_technology/health_information_technology_toolkit.asp
  16. Iowa Department of Public Health. Disease registry issue brief [Online]. [cited 2010]; Available from: UTL: https://idph.iowa.gov/Portals/1/Files/OHCT/Disease%20Registry%20Issue%20Brief-%20Executive%20Summary.pdf
  17. World Health Organization, Office of Cardiovasculr Diseases. MONICA Manual. Geneva, Switzerland: World Health Organization; 1999.
  18. Oveisgharan S, Shirani S, Ghorbani A, Soltanzade A, Baghaei A, Hosseini S, et al. Barthel index in a Middle-East country: Translation, validity and reliability. Cerebrovasc Dis 2006; 22(5-6): 350-4.
  19. Hosseini S, Baghbanian P. Assessment of predictive factors of death from myocardial infarction at 28 days. Research in Medical Sciences 2017; 8: 98-102. [In Persian].
  20. Sarrafzadegan N, Oveisgharan S, Toghianifar N, Hosseini S, Rabiei K. Acute myocardial infarction in Isfahan, Iran: hospitalization and 28th day case-fatality rate. ARYA Atheroscler 2007; 5(3): 495-9.
  21. Oveisgharan S, SarrafZadegan N, Shirani S, Hosseini S, Hasanzadeh P, Khosravi A. Stroke in Isfahan, Iran: Hospital admission and 28-day case fatality rate. Cerebrovasc Dis 2007; 24(6): 495-9.
  22. Mohammadian Hafshejani A, Sarrafzadegan N, Baradaran Attar Moghaddam HR, Hosseini S, Hosseini S. Gender difference in determinants of short-term survival of patients with acute myocardial infarction in Isfahan, Iran. J Isfahan Med Sch 2012; 30(209): 1611-22. [In Persian].
  23. Mohammadian Hafshejani A, Baradaran H, Sarrafzadegan N, Asadi Lari M, Ramezani A, Hosseini S, et al. Predicting factors of short-term survival in patients with acute myocardial infarction in Isfahan using a cox regression model. Iran J Epidemiol 2012; 8(2): 39-47. [In Persian].
  24. Mohammadian Hafshejani A, Baradaran Attar Moghaddam HR, Sarrafzadegan N, Bakhsi Hafshejani FA, Hosseini S, AsadiLari M, et al. Evaluation of short-term survival of patients with acute myocardial infarction and the differences between the sexes in Isfahan and Najaf Abad between (1999-2008). Razi J Med Sci 2012; 19(95): 25-34. [In Persian].
  25. Mohammadian-Hafshejani A, Baradaran-AttarMoghaddam H, Sarrafzadegan N, AsadiLari M, Roohani M, Allah-Bakhsi F, et al. Secular trend changes in mean age of morbidity and mortality from an acute myocardial infarction during a 10-year period of time in Isfahan and Najaf Abad. J Shahrekord Univ Med Sci 2013; 14(6): 101-14. [In Persian].
  26. European Society of Cardiology. EURObservational Research Programme [Online]. [cited 2016]; Available from: URL: https://www.escardio.org/portal/site/Escardio/menuitem.c9f480f01a3ca18798f54de7202031ca/?vgnextoid=5c4407daabb2b410VgnVCM1000004e03a8c0RCRD&vgnextchannel=2f468124b9945510VgnVCM1000005303a8c0RCRD&vgnextfmt=default&vgnextlocale=EN
  27. Noncommunicable Diseases and Mental Health, World Health Organization. STEPS-stroke: The WHO STEP wise approach to stroke surveillance. Geneva, Switzerland: World Health Organization; 2006.
  28. Giampaoli S, Hammar N, Adany R, De PC. Population-based register of stroke: Manual of operations. Eur J Cardiovasc Prev Rehabil 2007; 14(Suppl 3): S23-S41.
  29. Ringelstein EB, Meckes-Ferber S, Hacke W, Kaste M, Brainin M, Leys D. European stroke facilities survey: The German and Austrian perspective. Cerebrovasc Dis 2009; 27(2): 138-45.
  30. Cardiovascular Research Institute. Persian Registry Of cardioVascular disease (PROVE) [Online]. [cited 2015]; Available from: URL: http://prove.mui.ac.ir
  31. Jonsson A, Edner M, Alehagen U, Dahlstrom U. Heart failure registry: A valuable tool for improving the management of patients with heart failure. Eur J Heart Fail 2010; 12(1): 25-31.
  32. Laothavorn P, Hengrussamee K, Kanjanavanit R, Moleerergpoom W, Laorakpongse D, Pachirat O, et al. Thai acute decompensated heart failure registry (Thai ADHERE). CVD Prevention & Control 2010; 5(3): 89-95.
  33. Huffman DA. A method for the construction of minimum-redundancy codes. Proceedings of the IRE 1952; 40(9): 1098-101.
  34. Golin MJ, Kenyon C, Young NE. Huffman coding with unequal letter costs. Proceedings of the 34th Annual ACM Symposium on Theory of Computing; 2002 May 19-21; New York, NY.
  35. Arts DG, De Keizer NF, Scheffer GJ. Defining and improving data quality in medical registries: A literature review, case study, and generic framework. J Am Med Inform Assoc 2002; 9(6): 600-11.
  36. Fox KA, Eagle KA, Gore JM, Steg PG, Anderson FA. The global registry of acute coronary events, 1999 to 2009-GRACE. Heart 2010; 96(14): 1095-101.
  37. Gliklich RE, Dreyer NA, Leavy MB. Registries for evaluating patient outcomes: A user's guide. Rockville, MD: Agency for Healthcare Research and Quality; 2014.