Document Type : Case Report

Authors

1 Department of Pediatrics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran

2 Clinical Research Development Unit, Shahid Bahonar Hospital, Kerman University of Medical Sciences, Kerman, Iran

3 Center for Healthcare Data Modeling, Departments of Biostatistics and Epidemiology, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

10.48305/arya.2025.43587.3042

Abstract

Ventricular septal defect (VSD) is a common congenital heart defect. In large VSDs with significant left-to-right shunting, percutaneous closure can be an effective alternative to surgical repair. In some cases, percutaneous closure of septal defects is a successful treatment. Our main objective in this case report is to discuss the transcatheter closure of ventricular septal defects in a low-birth-weight infant. We are presenting the case of a 9-month-old male infant who is experiencing failure to thrive (FTT) alongside a significant ventricular septal defect (VSD). The patient successfully underwent percutaneous closure of the VSD using an antegrade approach with a symmetric device. Follow-up evaluations after the procedure confirmed that the closure was effective, the device was in the correct position, and pulmonary hypertension had resolved. As far as we know, this case represents one of the youngest and lowest-weight infants reported in Iran for successful percutaneous VSD closure instead of open surgery.

Keywords

1. Hoffman JI, Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol. 2002 Jun 19;39(12):1890-900. https://doi.org/10.1016/s0735-1097(02)01886-7
2. Butera G, Chessa M, Carminati M. Percutaneous closure of ventricular septal defects. State of the art. J Cardiovasc Med (Hagerstown). 2007 Jan;8(1):39-45. https://doi.org/10.2459/01.jcm.00
00247434.59451.d7
3. Narin N, Baykan A, Argun M, Ozyurt A, Pamukcu O, Bayram A, Uzum K. New modified balloon-assisted technique to provide appropriate deployment in the closure of large secundum atrial septal defect using amplatzer septal occluder in children. J Invasive Cardiol. 2014 Nov;26(11):597-602.
4. Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, editors. Moss & Adams’ Heart Disease in Infants, Children, and Adolescents, Including the Fetus and Young Adult. 10th ed. Philadelphia: Wolters Kluwer; 2022.
5. World Health Organization. WHO Child Growth Standards: Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. Geneva: World Health Organization; 2006.
6. Alshahrani D, Linnane N, McCrossan B, Oslizlok P, McMahon CJ, Walsh KP, et al. Transfemoral Perimembranous Ventricular Septal Defect Device Closure in Infants Weighing ≤ 10 kg. Pediatr Cardiol. 2023 Jun;44(5):1176-82. https://doi.org/10.1007/s00246-023-03100-5
7. Taşcı O, Pamukçu Ö, Narin N, et al. The Effect of Transcatheter Ventricular Septal Defect Closure on Children’s Appetite and Growth: A Single-Center Experience. Erciyes Med J. 2023;45(2):145-51. https://dx.doi.org/10.14744/etd.2022.41848
8. Munde K, Munde A, Paliwal M, et al. Percutaneous device closure of a perimembranous ventricular septal defect in an infant weighing less than 5 kg. AsiaIntervention. 2025;11(1):90-92. https://dx.doi.org/10.4244/AIJ-D-24-00038