Document Type : Original Article

Authors

1 Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

2 Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

3 Department of Biostatistics and Epidemiology, School of health, Isfahan University of Medical Sciences, Isfahan, Iran

4 Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

5 Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

6 Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

7 Pediatric Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

8 Students' Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

10.48305/arya.2025.43240.3010

Abstract

BACKGROUND: This study aims to explore the psychosocial factors related to the severity of pain in patients with non-cardiac chest pain (NCCP), providing insights to support more comprehensive and targeted management strategies.    
METHODS: This cross-sectional study was conducted at two university-affiliated hospitals. Patients diagnosed with NCCP, based on physical examination and angiographic findings, completed questionnaires assessing type D personality, cardiac anxiety, fear of bodily sensations, somatization, depression, and pain severity. Univariate and multiple logistic regression analyses were conducted to identify factors influencing pain severity levels.
RESULTS: A total of 156 males and 204 females, with a mean age of 55.76 ± 12.83 years, were divided into low-pain (N = 182) and high-pain (N = 178) groups. Higher education and being female were significantly associated with greater pain severity. Depression, type D personality, somatization, and cardiac anxiety were significantly correlated with pain severity. Multiple logistic regression analysis indicated that self-rated health (OR,: 2.14; 95% CI. :1.18-3.90), depression (OR-11.15; 95% CI-:1.09-1.22), type D personality (OR-: 1.90; 95% CI-: 1.06- 3.41), somatization (OR-: 1.03; 95% CI-: 1.01-1.06), and fear of bodily sensation (OR-: 1.90; 95% CI-: 1.06-3.41), were all associated with pain severity. 
CONCLUSION: This study concluded that type D personality, fear of bodily sensations, depression, somatization, cardiac anxiety, and poor self-rated health were associated with increased NCCP severity. By controlling the disease and managing related pain earlier, more coherent treatment strategies can be implemented, ultimately improving patients’ quality of life.

Keywords

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